نوع مقاله : اصیل پژوهشی
1 استادیار گروه زنان و زایمان، دانشکده پزشکی، دانشگاه علوم پزشکی ایران، تهران، ایران
2 دانشیار گروه زنان و زایمان، دانشکده پزشکی، دانشگاه علوم پزشکی ایران، تهران، ایران
3 . رزیدنت زنان و زایمان، دانشکده پزشکی، دانشگاه علوم پزشکی ایران، تهران، ایران
عنوان مقاله [English]
Introduction: Vaginal infections and discharge are among the most common complaints that bring the patient to the gynecologic clinics.The purpose of the present study is to evaluate pathogenic agents and risk factors of bacterial vaginosis.
Methods: A case- control study was performed on 200 patients. The case group (n=100) complained of vaginal discharge and bacterial vaginosis was the diagnosis , and the control group (n=100), did not have any vaginal discharge and had referred to the clinic just for seeking a contraceptive method. The vaginal samples were examined for vaginal PH and direct microscopic examination was done for gram stains, candidiasis, inflammatory cells, and presence of clue cells, red blood cells and white blood cells so whiff test and culture in different medias were performed.
Results: Anaerobic bacteria including peptostreptococcus, peptococcus, bacterioids, and obligate anaerobic lactobacillus were found in 8% of control group and 63% of study group. Difference in two groups was statistically significant. Lactobacillus was found in %81 of control group and %23 of study group with significant differences. Gardenella vaginalis was found in 88% of study group and 34% of control group. Bacterioid species were found in 15% of study group and 5% of control group. Seventy seven percent of participants were married for 6-20 years.41% of study group and 16% of control group had parity of 3-4 (P<0.05). IUD was used in 27% of study group and 17% of control group, respectively while condom and interrupted coitus were more common in the control group.
Conclusion: Anaerobic bacteria and gardenella vaginalis were more common in patients with non- specific vaginal discharge. Candom and coitus interruptus have protective effect on vaginal discharge, and IUD can increase its incidene.