میزان اضطراب ناشی از کرونا ویروس جدید (کووید 19) در بیماران مبتلا به سرطان پستان در زمان پاندمی کرونا

نوع مقاله : اصیل پژوهشی

نویسندگان

1 استادیار گروه جراحی، مرکز تحقیقات سلامت و بیماریهای زنان، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

2 استادیار گروه بیماری‌های عفونی، مرکز تحقیقات بیماریهای غیرواگیر، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

3 کارشناس بهداشت، مرکز تحقیقات سلامت و بیماریهای زنان، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

4 دانشجوی پزشکی، کمیته تحقیقات دانشجویی، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

5 کارشناس نرم‌افزار، معاونت پژوهشی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

6 6. کارشناس ارشد مدیریت خدمات بهداشتی و درمانی، واحد توسعه تحقیقات بالینی بیمارستان پیمانیه، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

چکیده

مقدمه: سرطان پستان رایج‌ترین سرطان در میان زنان است. اضطراب می‌تواند سیستم ایمنی بدن را تضعیف کرده و آنها را در برابر بیماری‌ها از جمله کرونا آسیب‌پذیر کند. مطالعه حاضر با هدف بررسی میزان اضطراب ناشی از کرونا ویروس جدید (کووید 19) در بیماران مبتلا به سرطان پستان در زمان پاندمی کرونا انجام شد.
روش‌کار: این مطالعه توصیفی - مقطعی در سال 1399 بر روی 102 نفر از بیماران مبتلا به سرطان پستان در شهرستان جهرم انجام شد. ابزار جمع‌آوری اطلاعات در این مطالعه، پرسشنامه اطلاعات دموگرافیک و پرسشنامه مقیاس اضطراب کرونا ویروس بود. طیف نمره‌دهی در این مطالعه بین 54-0 می‌باشد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 21) و آزمون‌های آماری تی تست و آنوا یا معادل ناپارامتریک آن انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: میانگین نمره اضطراب ناشی از ویروس کووید-19 در بیماران مبتلا به سرطان پستان 61/16±44/22 بود که پایین‌تر از حد متوسط قرار دارد. در بین مؤلفه‌های اضطراب، میانگین نمره علائم روانی (38/24±81/36) بیماران مبتلا به سرطان پستان بالاتر از علائم جسمانی (73/11±76/12) گزارش شد. بین متغیرهای دموگرافیک و اضطراب ناشی از ویروس کووید-19 ارتباط معنی‌داری مشاهده نشد (05/0<p).
نتیجه‌گیری: نتایج مطالعه حاضر نشان داد میزان اضطراب در زنان مبتلا به سرطان پستان در شهرستان جهرم کمتر از حد متوسط می‌باشد.
 

کلیدواژه‌ها


عنوان مقاله [English]

Anxiety caused by new coronavirus (Covid-19) in breast cancer patients during the coronavirus pandemic

نویسندگان [English]

  • Marzieh Haghbin 1
  • Alireza Abbasi 2
  • Elham Rafei 3
  • Alireza Kheradmand 4
  • Farshid Javdani 4
  • Naser Hatami 4
  • Parya Afraz 5
  • Navid Kalani 6
1 Assistant Professor, Department of Surgery, Women’s Health and Disease Research Center, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
2 Assistant Professor, Department of Infectious disease, Non-Communicable Diseases Research Center, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
3 B.Sc. in Health, Women’s Health and Disease Research Center, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
4 Medical Student, Student Research Committee, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
5 B.Sc. in software, Mashhad University of Medical sciences, Mashhad, Iran.
6 MSc in Health Services Management, Clinical Research Development Unit of Peymanieh Hospital, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
چکیده [English]

Introduction: Breast cancer is the most common cancer among women. Anxiety can weaken the body's immune system and make them vulnerable to the diseases such as coronavirus disease. This study was performed with aim to evaluate the level of anxiety caused by the new coronavirus (Covid-19) in patients with breast cancer during the coronavirus pandemic.
Methods: This descriptive cross-sectional study was performed in 2020 on 102 breast cancer patients in Jahrom. Data collection tools were Demographic Information Questionnaire and Coronavirus Disease Anxiety Scale (CDAS). Scoring range in this study was 0-54. Data were analyzed by SPSS software (version 21) and statistical tests of t-test and ANOVA or its non-parametric equivalent. p < 0.05 was considered statistically significant.
Results: The mean score of anxiety caused by Covid-19 virus 19 in patients with breast cancer was 22.44±16.61, which is lower than average level. Among the components of anxiety, the mean score of psychological symptoms (36.81±24.38) in patients with breast cancer was higher than physical symptoms (12.76±11.73). No significant relationship was observed between other demographic variables and anxiety caused by Coronavirus 19 (P>0.05).
Conclusion: The results of the present study showed that the level of anxiety in women with breast cancer in Jahrom is lower than average level.

کلیدواژه‌ها [English]

  • Anxiety
  • Breast Cancer
  • Coronavirus
  • COVID 19
  1. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; 579(7798):270-273.
  2. Join IF, Calendar P. Boosting Immunity: Functional Medicine Tips on Prevention & Immunity Boosting During the COVID-19 (Coronavirus) Outbreak. Functional Medicine; 2020.
  3. Human Coronavirus Types. https://www.cdc.gov/coronavirus/types.html (Accessed Feb 14, 2020).
  4. Makamure M, Makamure M, Mendiola W, Renteria D, Repp M, Willden A. A review of critical care nursing and disease outbreak preparedness. Dimens Crit Care Nurs 2013; 32(4):157-61.
  5. Terrizzi Jr JA, Shook NJ, McDaniel MA. The behavioral immune system and social conservatism: A meta-analysis. Evolution and Human Behavior 2013; 34(2):99-108.
  6. Mortensen CR, Becker DV, Ackerman JM, Neuberg SL, Kenrick DT. Infection breeds reticence: the effects of disease salience on self-perceptions of personality and behavioral avoidance tendencies. Psychol Sci 2010; 21(3):440-7.
  7. Schaller M, Murray DR. Pathogens, personality, and culture: disease prevalence predicts worldwide variability in sociosexuality, extraversion, and openness to experience. J Pers Soc Psychol 2008; 95(1):212-21.
  8. Lee SM, Kang WS, Cho AR, Kim T, Park JK. Psychological impact of the 2015 MERS outbreak on hospital workers and quarantined hemodialysis patients. Comprehensive psychiatry 2018; 87:123-7.
  9. Dong L, Bouey J. Public Mental Health Crisis during COVID-19 Pandemic, China. Emerg Infect Dis 2020; 26(7):1616-1618.
  10. Maunder R, Hunter J, Vincent L, Bennett J, Peladeau N, Leszcz M, et al. The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital. CMAJ 2003; 168(10):1245-51.
  11. Tam CW, Pang EP, Lam LC, Chiu HF. Severe acute respiratory syndrome (SARS) in Hong Kong in 2003: stress and psychological impact among frontline healthcare workers. Psychol Med 2004; 34(7):1197-204.
  12. Ackerman JM, Becker DV, Mortensen CR, Sasaki T, Neuberg SL, Kenrick DT. A pox on the mind: Disjunction of attention and memory in the processing of physical disfigurement. J Exp Soc Psychol 2009; 45(3):478-485.
  13. Kiecolt-Glaser JK, McGuire L, Robles TF, Glaser R. Emotions, morbidity, and mortality: new perspectives from psychoneuroimmunology. Annu Rev Psychol 2002; 53:83-107.
  14. Su TP, Lien TC, Yang CY, Su YL, Wang JH, Tsai SL, et al. Prevalence of psychiatric morbidity and psychological adaptation of the nurses in a structured SARS caring unit during outbreak: a prospective and periodic assessment study in Taiwan. J Psychiatr Res 2007; 41(1-2):119-30.
  15. Chong MY, Wang WC, Hsieh WC, Lee CY, Chiu NM, Yeh WC, et al. Psychological impact of severe acute respiratory syndrome on health workers in a tertiary hospital. The British Journal of Psychiatry 2004; 185(2):127-33.
  16. Wheaton MG, Abramowitz JS, Berman NC, Fabricant LE, Olatunji BO. Psychological predictors of anxiety in response to the H1N1 (swine flu) pandemic. Cognitive Therapy and Research. 2012; 36(3):210-8.
  17. Wu P, Fang Y, Guan Z, Fan B, Kong J, Yao Z, et al. The psychological impact of the SARS epidemic on hospital employees in China: exposure, risk perception, and altruistic acceptance of risk. The Canadian Journal of Psychiatry 2009; 54(5):302-11.
  18. Yip PS, Cheung YT, Chau PH, Law YW. The impact of epidemic outbreak: the case of severe acute respiratory syndrome (SARS) and suicide among older adults in Hong Kong. Crisis 2010; 31(2):86-92.
  19. Bansal N, Ghafur A. COVID-19 in oncology settings. Cancer Research, Statistics, and Treatment 2020; 3(5):13.
  20. Kamboj M, Sepkowitz KA. Nosocomial infections in patients with cancer. The lancet oncology 2009; 10(6):589-97.
  21. Li JY, Duan XF, Wang LP, Xu YJ, Huang L, Zhang TF, et al. Selective depletion of regulatory T cell subsets by docetaxel treatment in patients with nonsmall cell lung cancer. J Immunol Res 2014; 2014:286170.
  22. Longbottom ER, Torrance HD, Owen HC, Fragkou PC, Hinds CJ, Pearse RM, et al. Features of Postoperative Immune Suppression Are Reversible With Interferon Gamma and Independent of Interleukin-6 Pathways. Ann Surg 2016; 264(2):370-7.
  23. Sica A, Massarotti M. Myeloid suppressor cells in cancer and autoimmunity. Journal of autoimmunity 2017; 85:117-25.
  24. World Health Organization. Breast cancer: prevention and control. World Health Organization; 2019. Available at: http://www.who.int/cancer/detection/breastcancer/en/index1.html [accessed 11 Dec 2019]
  25. Liang W, Guan W, Chen R, Wang W, Li J, Xu K, et al. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol 2020; 21(3):335-337.
  26. Wang C, Pan R, Wan X, Tan Y, Xu L, McIntyre RS, et al. A longitudinal study on the mental health of general population during the COVID-19 epidemic in China. Brain Behav Immun 2020;87:40-48.
  27. Heather C. What a Terrible Time to Have Cancer: Falling Ill during the Corona Virus Crisis. Hallie Golden; 2020.
  28. BBC. Coronavirus: Cancer Pateints 'Coud Die Due to Surgery Delays'. BBC; 2020. Available from: http://www.bbc.com/news/uk-wales-52038230. [Last accessed on 2020 Apr 03].
  29. Sareen J, Erickson J, Medved MI, Asmundson GJ, Enns MW, Stein M, et al. Risk factors for post‐injury mental health problems. Depression and anxiety 2013; 30(4):321-7.
  30. Burgess C, Cornelius V, Love S, Graham J, Richards M, Ramirez A. Depression and anxiety in women with early breast cancer: five year observational cohort study. BMJ 2005; 330(7493):702.
  31. Alipour A, Ghadami A, Alipour Z, Abdollahzadeh H. Preliminary validation of the Corona disease anxiety scale (CDAS) in the Iranian sample. Quarterly Journal of Health Psychology 2020; 8(4):175-163.
  32. World Health Organization. Coronavirus disease 2019 (COVID-19): situation report, 69; 2020.
  33. Yao H, Chen JH, Xu YF. Rethinking online mental health services in China during the COVID-19 epidemic. Asian J Psychiatr 2020; 50:102015.
  34. Mirsalehian A, Dalvand M. History of bacterial infection diseases in Iran. Iranian Journal of Medical Microbiology 2018; 12(4):230-8.
  35. Van Bortel T, Basnayake A, Wurie F, Jambai M, Koroma AS, Muana AT, et al. Psychosocial effects of an Ebola outbreak at individual, community and international levels. Bull World Health Organ 2016; 94(3):210-4.
  36. Taylor MR, Agho KE, Stevens GJ, Raphael B. Factors influencing psychological distress during a disease epidemic: data from Australia's first outbreak of equine influenza. BMC Public Health 2008; 8:347.
  37. Xiao H, Zhang Y, Kong D, Li S, Yang N. Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Disease 2019 (COVID-19) Outbreak in January 2020 in China. Med Sci Monit 2020; 26:e923921.
  38. Sun L, Sun Z, Wu L, Zhu Z, Zhang F, Shang Z, et al. Prevalence and risk factors of acute posttraumatic stress symptoms during the COVID-19 outbreak in Wuhan, China. MedRxiv 2020.
  39. Hao F, Tan W, Jiang L, Zhang L, Zhao X, Zou Y, et al. Do psychiatric patients experience more psychiatric symptoms during COVID-19 pandemic and lockdown? A case-control study with service and research implications for immunopsychiatry. Brain Behav Immun 2020; 87:100-106.
  40. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. nature 2020; 579(7798):270-3.
  41. Vanni G, Materazzo M, Pellicciaro M, Ingallinella S, Rho M, Santori F, et al. Breast Cancer and COVID-19: The Effect of Fear on Patients' Decision-making Process. In Vivo 2020; 34(3 Suppl):1651-1659.
  42. Wang Y, Duan Z, Ma Z, Mao Y, Li X, Wilson A, et al. Epidemiology of mental health problems among patients with cancer during COVID-19 pandemic. Translational psychiatry 2020; 10(1):1-0.
  43. Jiang S, Shi Z, Shu Y, Song J, Gao GF, Tan W, et al. A distinct name is needed for the new coronavirus. Lancet 2020; 395(10228):949.
  44. Al Mohaissen M. Awareness among a Saudi Arabian university community of Middle East respiratory syndrome coronavirus following an outbreak. EMHJ-Eastern Mediterranean Health Journal 2017; 23(5):351-60.
  45. Huang Y, Zhao N. Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey. Psychiatry Res 2020; 288:112954.
  46. Al-Rabiaah A, Temsah MH, Al-Eyadhy AA, Hasan GM, Al-Zamil F, Al-Subaie S, et al. Middle East Respiratory Syndrome-Corona Virus (MERS-CoV) associated stress among medical students at a university teaching hospital in Saudi Arabia. Journal of infection and public health 2020; 13(5):687-691
  47. Aznab M. Evaluation of COVID 19 infection in 279 cancer patients treated during a 90-day period in 2020 pandemic. Int J Clin Oncol 2020; 25(9):1581-1586.