بررسی نقش و مکانیسم احتمالی عوامل تغذیه‌ای بر نسبت جنسیتی جنین

نوع مقاله : مروری

نویسندگان

1 دانشجوی کارشناسی ارشد علوم تغذیه، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 دانشجوی دکترای فیزیولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

3 دانشیار گروه زنان و مامایی، مرکز تحقیقات سلامت زنان، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

4 دانشیار گروه تغذیه، مرکز تحقیقات بیوشیمی تغذیه، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: بروز بیماری‌های خاص ژنتیکی که در جنس خاص تظاهر می‌کند و همچنین تغییرات نسبت جنسیتی در برخی کشورها، علاقه به مقوله تعیین جنسیت را افزایش داده است. روش‌های متفاوتی برای تعیین جنسیت وجود دارد که در این بین رژیم غذایی با توجه به عدم نیاز به تجهیزات خاص، سهولت، در دسترس و ارزان بودن آن، مورد توجه قرار گرفته است. مطالعه حاضر با هدف بررسی اینکه چه عوامل تغذیه ای می توانند بر نسبت جنسیتی تأثیرگذار باشند و مکانیسم احتمالی تأثیرگذاری آنها بر نسبت جنسیتی چیست انجام شد.
روش کار: جهت جستجو مقالات مرتبط با عوامل مختلف تأثیرگذار بر نسبت جنسیتی، واژه‌های BMI، Blood Glucose، Calcium، Calories، Diet، Estrogen، fatty Acids، Female Sex، Hormones،Follicle Stimulating Hormone، Luteal Hormone، Magnesium، Omega3،Sex Selection and Sodium، Sex Ratio، Progesterone، Potassium، Omega6 در پایگاه‌های داده  PubmedوGoogle Scholar بدون محدود کردن زمان و با واژگان کلیدی فوق جستجو شد و نتایج مهم‌ترین آن‌ها در مطالعه مورد بررسی قرار گرفت.
یافته‌ها: در برخی مطالعات از وضعیت بدنی، نوع و میزان انرژی رژیم غذایی مادر، میزان گلوکز خون، نوع اسیدهای چرب استفاده شده در رژیم غذایی و رژیم‌های غذایی منحصر به فرد به عنوان عوامل مؤثر بر نسبت جنسیتی ذکر شده است.
نتیجه‌گیری: مکانیسم اثرگذاری عوامل تغذیه‌ای بر نسبت جنسیتی به طور دقیق مشخص نیست. با این حال از آنجایی که در مقالات، از برخی عوامل تغذیه ای مؤثر بر نسبت جنسیتی، به عنوان عوامل مؤثر بر سطوح هورمون‌های جنسی نیز یاد شده است، بنابراین ممکن است یکی از مکانیسم‌های اثر عوامل تغذیه‌ای بر نسبت جنسیتی، از طریق اثر آنها بر هورمون‌های جنسی باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The role and possible mechanism of nutritional factors on sex ratio of the fetus: A review article

نویسندگان [English]

  • Ali Asghar Rashidi 1
  • Reza Mohebbati 2
  • Fatemeh Tara 3
  • Majid Ghayour Mobarhan 4
1 M.Sc Student of Nutrition Sciences, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
2 PhD Student of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Associate Professor, Department of Obstetrics and Gynecology, Women's Health Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
4 Associate Professor, Department of Nutrition, Nutrition Biochemistry Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
چکیده [English]

Introduction: The incidence of certain genetic diseases occurring in a certain sex as well as the variations of the sex ratio in some countries have led to an increased interest in sex determination. Different methods of sex determination are available, among which nutrition has been taken into consideration, since it doesn’t need any special equipment, cheapness, availability and ease of access. This study was performed with aim to investigate what dietary factors can affect the sex ratio and what are the possible mechanisms of their impact on the sex ratio.
Methods: To search the papers regarding the different factors affecting the sex ratio, without limiting the time, related keywords of BMI, Blood Glucose, Calcium, Calories, Diet, Estrogen, Fatty Acids, Female Sex Hormones, Follicle Stimulating Hormone, Luteal Hormone, Magnesium, Omega3, Omega6, Potassium, Progesterone, Sex Ratio, Sex Selection and Sodium were searched on PubMed and Google Scholar databases and the results from the most important entries were investigated in this study.
Results: In some studies, physical condition, type and calorie size of the mother’s diet, the blood glucose level, the types of ferry fatty acids in the diet and exclusive diets were considered as the effective factors influencing on the sex ratio.
Conclusion: The mechanism of dietary factors influencing on sex ratio is not exactly clear. However, since the articles have mentioned some nutritional factors affecting the sex ratio as the factors influencing sex hormone levels, so it is possible that one of the mechanisms of the effect of dietary factors on sex ratio is through their effect on sex hormones.

کلیدواژه‌ها [English]

  • Diet
  • Fetal sex
  • hormone
  • Sex ratio

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مجله زنان، مامایی و نازایی ایران
دوره 19، شماره 8
هفته چهارم اردیبهشت ماه 1395
اردیبهشت 1395
صفحه 14-27

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