عنوان مقاله [English]
Introduction: Hot flash is a medical complication of menopause and estrogens have been known as its main treatment. Likely due to increased risk of cancers such as breast cancer, use of estrogen is avoided by many patients. Hence, various medicines are taken in replacement of hormone therapy. The aim of this study is to compare the efficacy of Soy protein on menopausal hot flash.
Methods: A randomized double-blind clinical trial was done on menopausal women that referred for hot flash symptoms to Shahid Sadoughi Hospital in Yazd from 2007 to 2009. Ninety women, aged 49 to 55 years were selected and divided into two groups. Soy group (n=45) received 20 gram soy powder for 12 weeks, and placebo group (n= 45) received 20 gram Bread powder at the same time. After 12 weeks, the changes in frequency and intensity of hot flashes of two groups were compared. Data were analyzed by SPSS software version 15, T-student and X2 tests. p<0.05 was considerate significant.
Results: After 12 weeks, of 45 women in Soy group 34 (77.6%) have improved; while only 6 women (13.3%) in placebo had improvement (p=0.001).
Conclusion: Soy protein is a useful, costless and with lower side-effect diet in treatment of menopausal hot flash.