نوع مقاله : اصیل پژوهشی
نویسندگان
1 هسته تحقیقات سلامت خانواده و جوانی جمعیت، دپارتمان زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران
2 دانشگاه علوم پزشکی مشهد
3 دپارتمان زنان و مامایی،دانشگاه علوم پزشکی مشهد، مشهد ،ایران
چکیده
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
The aim of this study was to compare the effect of two different doses of estrogen (2.5 mg and 5 mg daily) in preventing the recurrence of adhesions after hysteroscopic lysis in Asherman's syndrome.
In this randomized controlled clinical trial study, patients with moderate and severe Asherman's syndrome were investigated in Imam Reza Hospital, Mashhad between 2016 and 2016.Patients underwent hysteroscopy to remove adhesions, all patients received postoperative estrogen therapy for 30 days (and medroxyprogesterone 10 mg daily for the last 10 days). Patients were randomly assigned to two groups of estrogen 2.5 mg and 5 mg daily. After the end of the treatment period, with hysteroscopy again, the state of the uterine cavity was checked and the response to the treatment was compared in terms of the return of adhesions and its severity in the two groups.The significance level of the results was considered p>0.05.
In this research, 30 women were compared. 20 people were in the 2.5 mg group and 10 people were in the 5 mg estrogen group.The average age of the patients was 33.40 years. The most common cause of Asherman in the 2.5 mg group was curettage (60%), and in the 5 mg group, other surgical procedures (60%).. The two groups did not have statistically significant differences in terms of confounding variables including age,
. In the examination of treatment response, there was no statistically significant difference between the two groups in terms of adhesion severity in repeated hysteroscopy (P=0.858) and response to treatment (P=0.714).
کلیدواژه‌ها [English]
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