بررسی تأثیر کپسول گیاه کیسه کشیش بر شدت دیسمنوره اولیه: یک کارآزمایی بالینی تصادفی شده

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 دانشیار گروه مامایی و بهداشت باروری، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 استاد گروه فارماکوگنوزی، مرکز تحقیقات علوم دارویی، دانشکده داروسازی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

4 استادیار گروه علوم پایه، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

5 استادیار گروه سلامت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران

چکیده

مقدمه: با توجه به شیوع بالای دیسمنوره اولیه و پیامدهای آن بر کیفیت زندگی و عوارض ناشی از مصرف داروهای ضد التهابی غیراستروئیدی، مطالعه حاضر با هدف بررسی تأثیر گیاه کیسه کشیش بر شدت دیسمنوره اولیه انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی سه‌سوکور در سال 1401 بر روی80 دختر مراجعه کننده به مراکز خدمات جامع سلامت دانشگاه علوم پزشکی کرمانشاه با سابقه دیسمنوره اولیه صورت گرفت. افراد در دو گروه 40 نفره مداخله و کنترل قرار گرفتند. گروه مداخله، کپسول‌های حاوی 400 میلی‌گرم عصاره هیدروالکلی گیاه کیسه کشیش و گروه کنترل، کپسول 250 میلی‌گرمی مفنامیک اسید را از روز اول قاعدگی هر ۸ساعت تا ۳ روز برای 2 دوره متوالی دریافت کردند. ابزار پژوهش، پرسشنامه مشخصات دموگرافیک، پرسشنامه وضعیت قاعدگی و فعالیت فیزیکی و مقیاس آنالوگ بصری بود. تجزیه و تحلیل داده­ ها با استفاده از نرم‌افزار آماری SPSS (نسخه 19) وآزمون­ های تی مستقل، کای دو، بونفرونی و تحلیل واریانس با اندازه‌گیری مکرر انجام شد. میزان p کمتر از05/0 معنى‌دار در نظر گرفته شد.
یافته­ها: دو گروه قبل از مداخله از نظر شدت درد مشابه بودند (689/0=p). آزمون واریانس دو عاملی نشان داد دو گروه بعد از مداخله به لحاظ شدت درد تفاوت معنی‌داری داشتند (001/0=p)، اما کاهش درد در گروه گیاه کیسه کشیش بیشتر بود.
نتیجه­گیری: گیاه کیسه کشیش می‌تواند شدت دیسمنوره اولیه را کاهش دهد؛ لذا توصیه می‌شود، پژوهش‌های بیشتری جهت تأیید اثربخشی و ایمنی گیاه کیسه کشیش صورت گیرد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effects of Capsella bursa pastoris Capsules on the Severity of Primary Dysmenorrhea: A Randomized Clinical Trial

نویسندگان [English]

  • Saeedeh Ahmadipoor 1
  • Fatemeh Nahidi 2
  • Faraz Mojab 3
  • Malihe Nasiri 4
  • Marzieh Kaboudi 5
1 M.Sc. student of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Associate professor, Department of Midwifery & Reproductive Health, Midwifery and Reproductive Health Research Centre, School of Nursing & Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Professor, Department of Pharmacognosy, Pharmaceutical Sciences Research Center, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Assistant professor, Department of Basic Sciences, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5 Assistant Professor, Department of Reproductive Health, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
چکیده [English]

Introduction: According to the high prevalence of primary dysmenorrhea and its consequences on the quality of life and the effects of nonsteroidal anti- inflammatory drugs consumption, the present study was performed with aim to investigate the effect of the capsella bursa-pastoris on the severity of primary dysmenorrhea.
Methods: This triple-blind clinical trial study was conducted in 2022 on 80 girls referred to the comprehensive health service centers of Kermanshah University of Medical Sciences with a history of primary dysmenorrhea. The participants were divided into two groups of 40 people, intervention and control. The intervention group received capsules containing 400 mg of hydroalcoholic extract of the "Capsella bursa pastoris" plant and the control group received 250 mg capsules of mefenamic acid every 8 hours for 3 days for 2 consecutive periods. The research tools were demographic profile questionnaire, menstrual status and physical activity questionnaire, and visual analog scale. Data were analyzed by SPSS software (version 19) and independent t-tests, chi-square, Bonferroni and analysis of variance with repeated measures. P<0.05 was considered statistically significant.
Results: Before the intervention, the two groups were similar in terms of pain intensity (p=0.689). The two-factor variance test showed that the two groups had a significant difference in terms of pain intensity after the intervention (p=0.001), but the reduction of pain was more in the capsella bursa-pastoris group.
Conclusion: The Capsella bursa-pastoris plant can reduce the severity of primary dysmenorrhoea; Therefore, it is recommended to conduct more researches to confirm the effectiveness and safety of the Capsella bursa pastoris plant.

کلیدواژه‌ها [English]

  • Capsella bursa-pastoris
  • Mefenamic acid
  • Menstruation
  • Primary dysmenorrhea

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مجله زنان، مامایی و نازایی ایران
دوره 26، شماره 10
دی 1402
صفحه 71-82

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