شیوع پاپیلوما ویروس تناسلی در زنان حاشیه‌نشین: یک مطالعه مروری سیستماتیک و متاآنالیز

نوع مقاله : مروری

نویسندگان

1 دانشجوی دکتری تخصصی بهداشت باروری، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 دانشیار، مرکز تحقیقات مامایی و بهداشت باروری، گروه مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 دانشیار، مرکز تحقیقات عوامل اجتماعی مؤثر بر سلامت، گروه مامایی و بهداشت باروری، دانشکده پزشکی، دانشگاه علوم پزشکی البرز، کرج، ایران.

چکیده

مقدمه: سرطان دهانه رحم به‌عنوان یک مشکل بهداشتی مهم در زنان شناخته شده است. عفونت با برخی از ژنوتیپ­ های ویروس پاپیلومای انسانی (HPV)، مهم‌ترین عامل خطر مرتبط با سرطان دهانه رحم می‌باشد. مطالعه حاضر با هدف برآورد شیوع HPV تناسلی در زنان حاشیه­ نشین انجام شد.
روش‌کار: در این مطالعه سیستماتیک و متاآنالیز از 20 فوریه تا 20 مارس 2023، پایگاه‌های اطلاعاتی Web of Science، Scopus، PubMed و Embase و موتور جستجوی Google scholar بدون اعمال محدودیت زمانی با استفاده از کلمات کلیدی از جمله "پاپیلوما ویروس"، "زگیل تناسلی" و "حاشیه­ نشین" و مترادف‌های مربوطه جستجو شدند. در معیارهای انتخاب، مطالعات مشاهده­ای در مورد شیوع پاپیلوما ویروس تناسلی در زنان حاشیه ­نشین گنجانده شدند. هتروژنیتی مطالعات با شاخص I2و آزمون کوکران Q ارزیابی شد. برای ارزیابی سوگیری انتشار مطالعات از نمودار قیفی و آزمون‌های Egger & Begg استفاده شد.
یافته ­ها: در نهایت 10 مطالعه با حجم نمونه کلی 65813، مطابق با هدف مطالعه حاضر باقی ماندند. نتایج متاآنالیز نشان داد، شیوع کلی HPV در زنان حاشیه­ نشین 17% (21-13%=CI) بود و ژنوتیپ HPV/16 با شیوع 18% (23-13%=CI) ژنوتیپ شایع در افراد مبتلا بود.
نتیجه ­گیری: به‌طور کلی، شیوع ابتلاء به ویروس پاپیلومای تناسلی در زنان حاشیه ­نشین نسبتاً بالا بود. این نتیجه می­ تواند برای سیاست­گذاران در برنامه ­ریزی استراتژی­ های پیشگیرانه از سرطان دهانه رحم در محیط ­های فقیرنشین و کم‌درآمد مفید باشد.

کلیدواژه‌ها

عنوان مقاله [English]

Prevalence of genital human papillomavirus in suburban women: A systematic review and meta-analysis

نویسندگان [English]

  • Marzieh Bagherinia 1
  • Mahrokh Dolatian 2
  • Zoherh Mahmoodi 3
  • Giti Ozgoli 2
1 PhD Candidate of Reproductive Health, Students Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Associate Professor, Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Associate Professor, Social Determinants of Health Research Center, Department of Midwifery and Reproductive Health, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
چکیده [English]

Introduction: Cervical cancer has been recognized as an important health problem in women. Infection with some genotypes of human papillomavirus (HPV) is the most important risk factor associated with cervical cancer. The present study was conducted with aim to estimate the prevalence of genital HPV in suburban women.
Methods: In this systematic and meta-analysis study from February 20 to March 20, 2023, databases of Web of Science, Scopus, PubMed and Embase and Google scholar search engine were searched without time restrictions using the keywords such as "papillomavirus", "genital wart" and "suburban population" and relevant synonyms. In the selection criteria, observational studies on the prevalence of genital papillomavirus in suburban women were included. Heterogeneity of the studies was evaluated with I2 and Cochran's Q test. Funnel plot and Egger & Begg tests were used to assess the publication bias of the studies.
Results: Finally, 10 studies with a sample size of 65,813 remained in accordance with the purpose of our study. The results of the meta-analysis showed that the overall prevalence of HPV in suburban women was 17% (95% CI: 13-21%) and HPV/16 genotype with a prevalence of 18% (95% CI: 13-23%) was the most common genotype in the affected people.
Conclusion: In general, the prevalence of genital papilloma virus infection was relatively high in suburban women. This result can be useful for policy makers in planning preventive strategies for cervical cancer in poor and low-income environments.

کلیدواژه‌ها [English]

  • Genital wart
  • Papillomavirus
  • Suburban
  • Women

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مجله زنان، مامایی و نازایی ایران
دوره 26، شماره 7
مهر 1402
صفحه 80-93

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