بررسی یافته‌های مربوط به تراکم غیرعادی پستان در ماموگرافی و ارتباط آن‌ها با میزان بدخیمی: یک مطالعه توصیفی در شهرستان جهرم، 1398

نوع مقاله : اصیل پژوهشی

نویسندگان

1 مربی گروه بیهوشی، مرکز تحقیقات مؤلفه‌های اجتماعی نظام سلامت، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

2 دانشجوی پزشکی، کمیته تحقیقات دانشجویی، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

3 دانشجوی کارشناسی مامایی، دانشکده مامایی، دانشگاه آزاد اسلامی واحد جهرم، جهرم، ایران.

4 استادیار گروه جراحی، مرکز تحقیقات سلامت و بیماری‌های زنان، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

چکیده

مقدمه: سرطان پستان، از رایج‌ترین سرطان‌ها در میان زنان در سراسر دنیا می‌باشد. ماموگرافی به‌عنوان ابزاری برای کشف زودرس سرطان‌های غیرقابل لمس پستان، هم در غربالگری و هم در کشف بیماری دارای ارزش تشخیصی است. مطالعه حاضر با هدف بررسی بررسی یافته‌های مربوط به تراکم غیرعادی در پستان و ارتباط آن ها با میزان بدخیمی انجام شد.
روش‌کار: این مطالعه توصیفی تحلیلی در سال 1398 بر روی 150 بیمار با نتیجه ماموگرافی تراکم غیرعادی پستان مراجعه کننده به کلینیک خاتم‌الانبیاء شهرستان جهرم صورت گرفت. متغیرهایی مانند ظاهر ضایعه در سونوگرافی، وجود یا عدم وجود توده، نوع توده و محل ضایعه در سونوگرافی مورد بررسی قرار گرفت و سپس ارزیابی هورمونی و پاتولوژی در صورت نیاز انجام شد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار SPSS (نسخه 19) و آزمون‌های کای اسکوئر و تی تست انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته ­ها: از 150 بیمار مورد بررسی، 134 مورد تراکم غیر عادی پستان در ماموگرافی مشاهده شد. توزیع سنی افرادی که یافته­ های ماموگرافی آنها نشان از وجود تراکم غیرعادی داشت، در مقایسه با بیماران بدون تراکم غیرعادی، تفاوت معنی‌داری نشان نداد. یافته ماموگرافی شامل نرمال بودن، خوش‌خیم، مشکوک، مرزی و بدخیم ارتباط معنی‌داری با وجود یا عدم وجود تراکم ناهمسان محوری داشت (001/0=p). نمره BI-RADS نیز ارتباط معنی‌داری با وجود یا عدم وجود تراکم ناهمسان محوری در ماموگرافی داشت (001/0=p). پاتولوژی فقط برای 21 مورد انجام شده بود. بر اساس این تست، حساسیت و اختصاصیت تراکم غیرعادی برای بدخیمی برابر 64/63% و 20% تعیین شد.
نتیجه­ گیری: با توجه به حساسیت و اختصاصیت مثبت بودن تراکم غیرعادی در ماموگرافی، برای بررسی­ های تکمیلی و بالا بردن ارزش تشخیصی، نیاز به استفاده از سایر روش ­های غربالگری در کنار ماموگرافی برای بیماران مستعد تراکم غیرعادی می‌باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The findings related to focal asymmetry density of breast in mammography and their relationship with malignancy rate: A descriptive study in Jahrom city, 2019

نویسندگان [English]

  • Navid Kalani 1
  • Maryam Sadat Hosseini 2
  • Zahra Mosalanezhad 3
  • Lohrasb Taheri 4
  • Marzieh Haghbeen 4
1 Instructor, Department of Anesthesiology, Research Center for Social Determinants of Health, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
2 General practitioner, Student Research Committee, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
3 Midwifery Bachelor Student, School of Midwifery, Islamic Azad University, Jahrom Branch, Jahrom, Iran.
4 Assistant Professor, Department of Surgery, Women’s Health and Diseases Research Center, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
چکیده [English]

Mammography has diagnostic value as a tool for the early detection of intangible breast cancers, both in screening and in the detection of disease. The present study was performed with aim to evaluate the findings related to focal asymmetry density of breast and their relationship with malignancy rate.
Methods: This descriptive analytical study was performed in 2019 on 150 patients with focal asymmetric density mammography referred to Khatam Al-Anbia Clinic of Jahrom city. Variables such as the appearance of the lesion on ultrasound, the presence or absence of a mass, the type of mass and the location of the lesion on ultrasound were examined and then hormonal and pathological evaluation was performed if necessary. Data analysis was done using SPSS software (version 19) and Chi-square and t-test. P<0.05 was considered statistically significant.
Results: Out of 150 patients, 134 cases of focal asymmetry density (FAD) were observed on mammography. The age distribution of people whose mammographic findings showed the presence of FAD did not show a significant difference compared to patients without FAD (P=0.728). The outer upper quadrant or UOQ with 84 cases (56%) is the most common site of FAD involvement. Mammographic findings including normal, benign, suspected, borderline and malignant were significantly associated with the presence or absence of FAD (P=0.001). BI-RADS score was also significantly associated with the presence or absence of FAD in mammography (P=0.0001). The pathology was performed only for 21 cases. Based on this test, the sensitivity and specificity of focal asymmetry density for malignancy were determined as 63.64% and 20.00%.
Conclusion: Considering to the sensitivity and specificity of positive focal asymmetric density in mammography, for additional studies and to increase the diagnostic value, it is necessary to use other screening methods along with mammography for patients prone to focal asymmetric density.

کلیدواژه‌ها [English]

  • Breast cancer
  • Mammography
  • Physical Examination

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مجله زنان، مامایی و نازایی ایران
دوره 26، شماره 7
مهر 1402
صفحه 32-43

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