بررسی اثربخشی کپسول خوراکی عصاره آبی الکلی پیاز قرمز بر قند خون زنان مبتلا به دیابت بارداری تحت درمان با رژیم غذایی

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 دانشیار گروه علوم دارویی در طب ایرانی، دانشکده طب ایرانی و مکمل، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

3 مربی گروه پرستاری، مرکز تحقیقات مراقبت مبتنی بر شواهد، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

4 استاد گروه زنان و مامایی، مرکز تحقیقات سلامت زنان، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

5 استادیار گروه مامایی، مرکز تحقیقات مراقبت‌های پرستاری و مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: مادران مبتلا به دیابت بارداری و نوزادان آن‌ها در معرض عوارض مادری و نوزادی قابل توجهی هستند. مطالعه حاضر با هدف تعیین تأثیر کپسول خوراکی عصاره آبی الکلی پیاز قرمز بر قندخون زنان مبتلا به دیابت بارداری تحت درمان با رژیم غذایی انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی تصادفی سه­ سوکور در سال 1401-1399 بر روی 60 نفر از زنان مبتلا به دیابت بارداری شهر مشهد انجام شد. مادران واجد شرایط 24-30 هفته، به­ روش در دسترس و به‌صورت تصادفی در دو گروه 30 نفره مداخله یا دارونما قرار گرفتند و به‌مدت 4 هفته، روزی 2 نوبت کپسول 500 میلی ­گرمی عصاره پیاز قرمز یا دارونما را مصرف کردند. قبل، 2 و 4 هفته بعد از مطالعه، قندخون ناشتا و 2 ساعت بعد از غذا بررسی­ شد. تجزیه و تحلیل داده­ ها با استفاده از نرم‌افزار آماری SPSS (نسخه 16) و آزمون‌های کای دو، تی مستقل و من ویتنی انجام شد. میزان p کمتر از 05/0 معنا‌دار در نظر گرفته شد.
یافته ­ها: تفاوت میانگین قند خون ناشتای 2 و 4 هفته بعد نسبت به قبل از مطالعه در گروه مداخله نسبت به گروه دارونما اختلاف آماری معنی‌داری داشت (05/0>p)، اما تفاوت میانگین قندخون 2 ساعت بعد از غذای 2 و 4 هفته بعد نسبت به قبل از مطالعه در گروه مداخله نسبت به گروه دارونما اختلاف آماری معنی‌داری نداشت (05/0<p).
نتیجه ­گیری: با توجه به تأثیر عصاره پیاز قرمز در کاهش قندخون ناشتا در زنان مبتلا به دیابت بارداری، توصیه می­ شود که مصرف آن در مراکز بهداشتی درمانی آموزش داده شود. 

کلیدواژه‌ها

عنوان مقاله [English]

The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet

نویسندگان [English]

  • Farzaneh Salajegheh Tezerji 1
  • Roshanak Salari 2
  • Seyed Reza Mazloum 3
  • Farideh Akhlaghi 4
  • Raheleh Babazadeh 5
1 M.Sc. Student of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Associate Professor, Department of Pharmaceutical Sciences in Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Instructor, Department of Nursing, Evidence-Based Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Professor, Department of Obstetrics and Gynecology, Women's Health Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
5 Assistant Professor, Department of Midwifery, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction: Mothers with gestational diabetes and their babies are exposed to significant maternal and neonatal complications. This study was conducted with aim to determine the effect of oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet.
Methods: This triple-blind randomized clinical trial study was conducted in 2021-2022 on 60 women with gestational diabetes in Mashhad. Eligible mothers at 24 to 30 weeks of gestation were randomly divided into two groups of 30 people, intervention or placebo, and took 500 mg capsules of red onion extract or placebo twice a day for 4 weeks. Fasting blood sugar was checked before, two weeks and four weeks after the study, and two hours after meals. Data analysis was done using SPSS statistical software (version 16) and Chi-square, Independent t and Mann-Whitney tests. P<0.05 was considered statistically significant.
Results: There was a statistically significant difference in the intervention group compared to the placebo group in the mean fasting blood sugar two and four weeks after the study (P<0.05). However, there was no statistically significant difference in the intervention group compared to the placebo group in the mean blood sugar two hours after a meal two and four weeks later compared to before the study (P>0.05).
Conclusion: Considering the effect of red onion extract in reducing fasting blood sugar in women with gestational diabetes, it is recommended to teach its use in health centers.

کلیدواژه‌ها [English]

  • Blood Glucose
  • Diet Therapy
  • Gestational Diabetes
  • Red Onion

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مجله زنان، مامایی و نازایی ایران
دوره 26، شماره 6
شهریور 1402
صفحه 72-82

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