فرآیند بلوغ در کودکان حاصل روش‌های کمک باروری: یک مطالعه مروری

نوع مقاله : مروری

نویسندگان

1 استادیار گروه مامایی و بهداشت باروری، مرکز تحقیقات مراقبت‌های پرستاری و مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران.

2 دانشجوی دکتری تخصصی بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران.

چکیده

مقدمه: کیفیت بلوغ می‌تواند سلامت جنسی و باروری فرزندان را تحت تأثیر قرار دهد. شواهد محدودی در مورد خطرات مرتبط با استفاده از روش‌ها­ی کمک باروری (ART) بر فرآیند بلوغ وجود دارد. مطالعه مروری حاضر با هدف بررسی فرآیند بلوغ در کودکان حاصل ART انجام شد.
روشکار: در این مطالعه مروری جهت یافتن مقالات مرتبط با موضوع فرآیند بلوغ در کودکان حاصل ART، پایگاه ­های اطلاعاتی Web of Science، Scopous، Proquest و Pubmed و پایگاه­ های فارسی SID و Magiran و موتور جستجوی Google Scholar برای یافتن مطالعات منتشر شده در بازه سال‌های 2022-1970 با استفاده از کلمات کلیدی انگلیسی: Assisted Reproductive Technology، In vitro fertilisation،Intracytoplasmic sperm injection، puberty، Tanner و adolescent و معادل فارسی آنها شامل: روش‌های کمک باروری، لقاح داخل آزمایشگاهی، تزریق داخل سیتوپلاسمی اسپرم، بلوغ، تانر و نوجوان جستجو شدند.
یافته­ ها: در مجموع از بین 1438 مقاله یافت شده، 10 مقاله واجد شرایط پژوهش بود و برای این مطالعه انتخاب شدند. شیوع اختلالات بلوغ در کودکان ART در مقایسه با کودکان حاصل بارداری نرمال تفاوتی نداشت. مراحل تانر، رشد استخوانی، وضعیت هورمونی در بین نوجوان حاصل ART مشابه جمعیت نرمال بود، اگرچه دختران حاصل ART در معرض بلوغ زودتر و پسران در معرض تفاوت اندک در هورمون‌های جنسی در مقایسه با کودکان حاصل بارداری نرمال بودند.
نتیجه گیری: اگرچه بسیاری از مطالعات تفاوت قابل توجهی در فرآیند بلوغ نوجوانان ART در مقایسه با دیگر نوجوانان نشان نداد، اطلاعات در مورد پیگیری طولانی‌مدت محدود است. بنابراین پیگیری طولانی‌مدت کودکان ART تا زمان تکمیل بلوغ به تفکیک جنسیت کودک و روش‌های کمک باروری ضروری است.

کلیدواژه‌ها


عنوان مقاله [English]

Puberty process in children born from Assisted Reproductive Technologies: a review study

نویسندگان [English]

  • Mitra Savabi esfahani 1
  • Maryam Heidari Sarvestani 2
  • Fatemeh Mokhtari 2
1 Assistant Professor, Department of Midwifery and Reproductive Health, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences. Isfahan, Iran.
2 PhD student of Reproductive Health, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.
چکیده [English]

Introduction: The quality of puberty can affect the sexual health and fertility of children. There is limited evidence about the risks associated with the use of assisted reproductive methods (ART) on the process of puberty. This review study was conducted with aim to investigate the puberty process in ART children.
Methods: In this review study, to find the related articles regarding the puberty process in ART children, the databases of Web of Science, Scopous, Proquest and Pubmed and Persian databases of SID and Magiran and Google Scholar search engine were searched to find published studies using English keywords: Assisted Reproductive Technology, In vitro fertilization, Intracytoplasmic sperm injection, puberty, Tanner and adolescent and their Persian equivalents.
Results: In total, among 1438 articles found, 10 articles were eligible for the research and were selected for this study. The prevalence of puberty disorders in ART children was not different compared to children resulting from spontaneous pregnancy. Tanner's stages, bone growth, hormonal status among adolescents resulting from ART were similar to the normal population, although in girls resulting from ART were exposed to earlier puberty and boys were exposed to small differences in sex hormones compared to children resulting from spontaneous pregnancy.
Conclusion: Although many studies did not show a significant difference in the puberty process of ART adolescents compared to other adolescents, information on long-term follow-up is limited. Therefore, it is necessary to long-term follow-up of ART-born children until completion of puberty by child's sex and ART types.

کلیدواژه‌ها [English]

  • Adolescent
  • Assisted Reproductive Technology
  • ICSI
  • In Vitro Fertilization
  • Puberty
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