مقایسه عوارض تنفسی و عفونی نوزادان نارس مادران مبتلا به بیماری در دوران حاملگی با مادران سالم

نوع مقاله : اصیل پژوهشی

نویسندگان

1 استاد گروه نوزادان، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران

2 استادیار گروه کودکان، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: بیماری‌های مادر در دوران بارداری، اثرات متعددی بر روی جنین و زندگی پس از تولد آن داشته و از طرفی مشکلات تنفسی و عفونی در نوزادان نارس بسیار شایع است، لذا مطالعه حاضر با هدف مقایسه این دو مشکل شایع در مادران با حاملگی دارای مشکل و نرمال انجام شد.
روش‌کار: در این مطالعه توصیفی گذشته‌نگر نوزادان نارس بستری در بخش NICU بیمارستان قائم (عج) مشهد طی سال‌های 1400-1393 مورد بررسی قرار گرفتند و اطلاعات مربوط به مطالعه شامل اطلاعات مادری (سن مادر، نوع زایمان، بیماری­ های مادر و عوارض بارداری) و نوزادی (مشکلات تنفسی، کشت خون، شمارش کامل سلولی، CRP و ESR) ثبت گردید. سپس مشخصات نوزادان در دو گروه مادران سالم و مادران مبتلا به بیماری­ های شایع بارداری با یکدیگر مقایسه شد. تجزیه و تحلیل داده­ ها با استفاده از نرم‌افزار آماری SPSS (نسخه 26) و آزمون های تی تست مستقل و کای دو انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته­ ها: در بررسی 982 مادر و نوزاد، در گروه مادران سالم و مبتلا به بیماری به‌ترتیب متوسط سن حاملگی  93/31 و 95/30 هفته، بروز سندرم زجر تنفسی در 39 (5/32%) و 357 (9/56%) نوزاد، دیسترس تنفسی غیراختصاصی در 13 (8/7%) و 105 (9/12%) نوزاد، افزایش فشار ریوی اولیه در صفر و 22 (7/2%) نوزاد، سپسیس در 37 (4/22%) و 219 (8/26%) نوزاد و بروز مننژیت در 2 (2/1%) و 15 (8/1%) نوزاد گزارش گردید (001/0>p).
نتیجه­ گیری: نارسی، شدت آن و مشکلات همراه آن در نوزادان مادران همراه با مشکلات دوران بارداری افزایش می­ یابد و مشکلات تنفسی، عفونی و حمایت تنفسی و مراقبت‌های لازم نیز بیشتر می­ گردد.

کلیدواژه‌ها

عنوان مقاله [English]

Respiratory and infectious complications of premature neonates of pregnant mothers with disease during pregnancy and compare with healthy mothers

نویسندگان [English]

  • Hasan Boskabadi 1
  • Nafiseh Pourbadakhshan 2
1 Professor, Department of Pediatric, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Assistant Professor, Department of Pediatric, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction: Maternal diseases during pregnancy have many effects on the fetus and infant, and on the other hand, respiratory and infectious problems are very common in premature neonates, so this study was performed with aim to compare these two common problems in mothers with normal and problematic pregnancies.
Methods: In this retrospective descriptive study, the premature neonates hospitalized in the NICU of Ghaem Hospital, Mashhad during 2014-2022 were examined, and the information related to the study, including maternal information (mother's age, type of delivery, maternal diseases  and pregnancy complications) and newborn information (respiratory problems, blood culture, complete blood cell count, C-reactive protein(CRP) and Erythrocyte Sedimentation Rate ( ESR)) were recorded. Then the neonates' characteristics in the two groups of healthy mothers and mothers with common pregnancy diseases were compared. Data were analyzed by SPSS (version 26) and Independent t-test and Chi-square test. P<0.05 was considered statistically significant.
Results: From a total of 982 mothers and newborns, mean gestational age in the group of healthy and diseased mothers was 31.93 and 30.95 weeks, the incidence of respiratory distress syndrome was reported in 39 (32.5%) and 357 infants (56.9%), non-specific respiratory distress in 13 (7.8%) and 105 infants (12.9%), primary pulmonary hypertension in 0 and 22 infants (2.7%), sepsis in 37 (22.4%) and 219 infants (26.8%), and the incidence of meningitis in 2 (1.2% ) and 15 infants (1.8%), respectively (P<0.001)
Conclusion: Prematurity, its severity and related problems increase in infant of mothers with problems during pregnancy. Respiratory and infectious problem, respiratory support and necessary care also increase.

کلیدواژه‌ها [English]

  • Meningitis
  • Pregnancy complications
  • Prematurity
  • Respiratory distress syndrome
  • Sepsis

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مجله زنان، مامایی و نازایی ایران
دوره 25، شماره 10
دی 1401
صفحه 1-9

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