بررسی ارتباط بین گروه‌های خونی مادر و برخی عوارض نامطلوب بارداری

نوع مقاله : اصیل پژوهشی

نویسندگان

1 استادیار پژوهشی اپیدمیولوژی، مرکز تحقیقات عوامل اجتماعی مؤثر بر سلامت، پژوهشکده علوم و فناوری بهداشت، دانشگاه علوم پزشکی همدان، همدان، ایران.

2 متخصص زنان و زایمان، دانشکده پزشکی، دانشگاه علوم پزشکی یاسوج، یاسوج، ایران.

3 متخصص زنان و زایمان، دانشکده پزشکی، دانشگاه علوم پزشکی ایران، تهران، ایران.

4 پزشک عمومی، دانشکده پزشکی، دانشگاه علوم پزشکی زاهدان، زاهدان، ایران.

5 دانشیار گروه زنان و مامایی، مرکز تحقیقات بیماری‌های عفونی و گرمسیری، دانشکده پزشکی، دانشگاه علوم پزشکی زاهدان، زاهدان، ایران. دانشکده پزشکی، دانشگاه علوم پزشکی ایران، تهران، ایران.

چکیده

مقدمه: بین گروه ­های خونی ABO و افزایش حساسیت به بیماری­ های خاص از جمله حوادث قلبی عروقی، عفونت­ های ویروسی و باکتریایی، سرطان کولورکتال، آنوریسم داخل جمجمه و بیماری­ های ترومبوآمبولی، ارتباط قوی وجود دارد. مطالعه حاضر با هدف بررسی ارتباط بین گروه­ های خونی مادر و عوارض نامطلوب بارداری انجام گرفت.
روش‌کار: در این مطالعه مقطعی (توصیفی - تحلیلی) و گذشته‌نگر، پرونده 400 نفر از بیمارانی که در سال 98-1396 جهت زایمان به بیمارستان علی ابن ابی طالب زاهدان مراجعه کردند، وارد مطالعه شدند. متغیرهای این مطالعه شامل: گروه­ های خونی ABO، پره‌اکلامپسی، اکلامپسی، دکولمان، دیابت حاملگی، زایمان زودرس و محدودیت رشد داخل رحمی بود. ابزار جمع‌آوری داده ­ها شامل فرم اطلاعاتی بود که اطلاعات مورد نیاز وارد آنها شد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 22) و آزمون کای دو انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته­ ها: از مجموع 400 زن باردار با میانگین سنی 53/7±09/33 سال، 153 نفر (3/38%) دارای گروه خونی O، 116 نفر (0/29%) B، 97 نفر (3/24%) A و 34 نفر (5/8%) AB بود. بین گروه­های خونی ABO و پره‌اکلامپسی (848/0=p)، دکولمان (833/0=p)، زایمان زودرس (705/0=p) و محدودیت رشد داخل رحمی (214/0=p) ارتباط آماری معنی‌داری وجود نداشت، ولی دیابت حاملگی (049/0=p) و اکلامپسی (039/0=p) با گروه‌های خونی ارتباط معنی‌داری داشتند.
نتیجه­ گیری: بین پره‌اکلامپسی، دکولمان، زایمان زودرس و محدودیت رشد داخل رحمی با گروه­ های خونی ABO اختلاف معنی‌داری وجود نداشت، اما بین اکلامپسی و دیابت حاملگی با گروه­ های خونی ABO اختلاف معنی‌داری وجود داشت.

کلیدواژه‌ها

عنوان مقاله [English]

The Relationship between Maternal Blood Group and Some Adverse Outcomes of Pregnancy

نویسندگان [English]

  • Erfan Ayubi 1
  • Zahra Asadi Kalameh 2
  • Behnaz Mohabbatian 3
  • Atefeh Khanezaei 4
  • Farahnaz Farzaneh 5
1 Assistant Professor, Departments of Epidemiology, Research Center for Social Factors Affecting Health, Research Institute of Health Sciences and Technology, Hamadan University of Medical Sciences, Hamadan, Iran.
2 Gynecologist, Faculty of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran.
3 Gynecologist, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
4 General Physician, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
5 Associate Professor, Department of Obstetrics and Gynecology, Infectious and Tropical Disease Research Center, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: There is a strong association between ABO blood groups and increased susceptibility to certain diseases including cardiovascular events, viral and bacterial infections, colorectal cancer, intracranial aneurysms and thromboembolic diseases. The present study was performed aimed to investigate the relationship between maternal blood groups and adverse pregnancy complications.
Methods: In this cross-sectional (descriptive-analytical) and retrospective study, the file of 400 pregnant women referred to the maternity hospital of Ali Ebn Abi Taleb Hospital of Zahedan from 2017 to 2019 were included. The variables of this study were ABO blood groups, preeclampsia, eclampsia, placental abruption, gestational diabetes mellitus, preterm labor and intrauterine growth restriction. The data collection tool included an information form in which the required information was entered. Data were analyzed by SPSS (version 22) and chi-square test. P<0.05 was considered statistically significant.
Results: Out of a total of 400 pregnant women with a mean age of 33.09±7.53 years, 153 (38.3%) had blood type O, 116 (29%) B, 97 (24.3%) A and 34 (8.5%) AB. The relationship between ABO blood groups and preeclampsia (p = 0.848), placental abruption (p = 0.833), preterm birth (p = 0.705) and intrauterine growth restriction (p = 0.214) was not statistically significant, but gestational diabetes (p=0.049) and eclampsia (p=0.039) had a significant relationship with blood groups.
Conclusion: There was no significant difference between preeclampsia, placental abruption, preterm labor and intrauterine growth restriction with ABO blood groups, but there was a significant difference between eclampsia and gestational diabetes with ABO blood groups.

کلیدواژه‌ها [English]

  • ABO blood group
  • Eclampsia
  • Fetal Growth Retardation
  • Gestational Diabetes
  • Placenta Abruption
  • Preeclampsia
  • Preterm delivery

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مجله زنان، مامایی و نازایی ایران
دوره 25، شماره 9
آذر 1401
صفحه 51-58

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