مقایسه سطح سرمی سدیم و پتاسیم در مادران با زایمان ترم و زودرس: یک مطالعه مورد شاهدی

نوع مقاله : اصیل پژوهشی

نویسندگان

1 مربی گروه مامایی، دانشگاه آزاد اسلامی واحد گناباد، گناباد، ایران.

2 استادیار گروه بهداشت باروری، مرکز تحقیقات توسعه اجتماعی و ارتقای سلامت، دانشکده پزشکی، دانشگاه علوم پزشکی گناباد، گناباد، ایران.

3 دکترای تخصصی فیزیولوژی، دانشکدة پزشکی، دانشگاه علوم پزشکی گناباد، گناباد، ایران.

4 استادیار گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی گناباد، گناباد، ایران.

چکیده

مقدمه: زایمان زودرس، نگرانی شایع سازمان جهانی بهداشت است. پژوهش­های انجام گرفته نشان دادند در عضلات صاف رحم کانال­های سدیم و پتاسیم قرار رفته که در بروز انقباضات رحمی نقش دارند، لذا مطالعه حاضر با هدف بررسی سطح سرمی سدیم و پتاسیم با زایمان زودرس انجام گرفت.
روشکار: این مطالعه مورد شاهدی در سال­های 99-1398 بر روی 86 زن باردار مراجعه‌کننده به بیمارستان علامه بهلول گناباد، در دو گروه زایمان ‌زودرس و زایمان ترم انجام گرفت. دو گروه از نظر متغیرهای شاخص توده بدنی ابتدای بارداری، رتبه بارداری و زایمان، سطح تحصیلات، میزان درآمد و وضعیت اشتغال، همسان‌‌سازی گروهی شدند. نمونه خون از مادران بعد از کسب معیارهای ‌ورود در زمان پذیرش در لیبر، جهت بررسی سطح سرمی سدیم و پتاسیم گرفته شد. اطلاعات دموگرافیک و مامایی با استفاده از پرسشنامه و پرونده بستری بیمار جمع‌آوری شد. تجزیه و تحلیل داده­ها با استفاده از نرم‌افزار آماری SPSS (نسخه 26) و آزمون­های من‌ویتنی، کای دو و فیشر انجام گرفت. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافتهها: میانگین سطح سرمی سدیم در گروه مورد (11/21±98/123 میلی‌اکی والان بر لیتر) پایین‌تر از گروه شاهد (39/11±43/131 میلی‌اکی والان بر لیتر) و میانگین سطح سرمی پتاسیم در گروه مورد (92/5±66/4 میلی‌اکی والان بر لیتر) بیشتر از گروه شاهد (34/0±82/3 میلی‌اکی والان بر لیتر) بود، اما این اختلاف­ها از نظر آماری معنادار نبود (05/0>p).
نتیجهگیری: بین سطح سرمی سدیم و پتاسیم با زایمان زودرس ارتباطی وجود ندارد. برای بررسی ارتباط سدیم و پتاسیم سرم مادر با زایمان زودرس، نیاز به انجام تحقیقات بیشتر و بررسی سطح داخل سلولی سدیم و پتاسیم است.

کلیدواژه‌ها


عنوان مقاله [English]

Serum sodium and potassium levels in mothers with term and preterm delivery: a case-control study

نویسندگان [English]

  • Haniye Gohari 1
  • Roghaieh Rahmani Bilandi 2
  • Abasali Abasnezad 3
  • Azamsadat Mahmodian 4
1 Instructor, Department of Midwifery, Gonabad Branch, Islamic Azad University, Gonabad, Iran.
2 Assistant Professor, Department of Reproductive Health, Social Development and Health Promotion Research Center, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
3 PhD of Physiology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
4 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
چکیده [English]

Introduction: Preterm labor is a common concern of the World Health Organization. Studies have shown that Potassium and sodium channels in the smooth muscles of the uterus are involved in causing uterine contractions. Therefore, this study was performed with aim to evaluate the serum levels of sodium and potassium in preterm labor.
Methods: This case-control study was performed on 86 pregnant women referred to Gonabad Allameh Behlool Hospital in 2019-2020 in two groups of preterm and term delivery. The two groups were matched in terms of body mass index in early pregnancy, number of pregnancies and deliveries, level of education, income, and employment status. Blood sample was taken from the mothers after obtaining the inclusion criteria at the time of admission in labor to assess serum sodium and potassium levels. Demographic and midwifery information were collected using a questionnaire and patient's file. Data were analyzed by SPSS statistical software (version 26), and Mann-Whitney, Chi-square and Fisher tests. P< 0.05 was considered statistically significant.
Results: The mean serum sodium level in the case group (123.98±21.11 mEq/L) was lower than the control group (131.43±11.39 mEq/L) and the mean serum potassium level in the case group (4.66±5.92 mEq/L) was more than the control group (3.82±0.34 mEq/L) but these differences were not statistically significant (p> 0.05).
Conclusion: There is no relationship between serum sodium and potassium levels with preterm delivery. To investigate the relationship between maternal serum sodium and potassium and preterm delivery, further research is needed to evaluate the intracellular level of sodium and potassium.

کلیدواژه‌ها [English]

  • electrolyte
  • Potassium
  • Preterm delivery
  • sodium
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