مقایسه اثر اندانسترون و طب فشاری K-K9 با اندانسترون در درمان تهوع و استفراغ بارداری

نوع مقاله : اصیل پژوهشی

نویسندگان

1 کارشناس ارشد مامایی، مرکز تحقیقات ارتقاء سلامت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران.

2 دکترای تخصصی بهداشت باروری، مرکز تحقیقات ارتقاء سلامت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، اهواز، ایران.

3 کارشناس ارشد آمار زیستی، دانشکده بهداشت، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران.

چکیده

مقدمه: تهوع و استفراغ بارداری، یکی از شایع­ترین مشکلات دوران بارداری می­باشد. با توجه به اینکه پژوهشی در مورد استفاده از یک روش ترکیبی از طب فشاری و داروی ضدتهوع و استفراغ در کاهش تهوع و استفراغ بارداری وجود ندارد، مطالعه حاضر با هدف مقایسه اثر اندانسترون و طب فشاری K-K9 با اندانسترون در درمان تهوع و استفراغ بارداری انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی تصادفی در سال 98-1397 بر روی 84 زن باردار مراجعه‌کننده به بیمارستان­های آموزشی اهواز انجام شد. افراد در دو گروه اندانسترون با طب فشاری K-K9 و اندانسترون به‌تنهایی قرار گرفتند. شدت و تعداد دفعات تهوع و استفراغ افراد توسط پرسشنامه رودز به‌مدت 8 روز ثبت شد. در روزهای 5-1 به هر دو گروه، قرص اندانسترون 4 میلی‌گرم هر 8 ساعت داده شد و برای گروه اندانسترون با طب فشاری K-K9 علاوه بر قرص اندانسترون، طب فشاری K-K9 توسط واحد پژوهش انجام شد. در روزهای 8-6 در دو گروه مداخله­ای صورت نگرفت. تجزیه و تحلیل داده­ها با استفاده از نرم‌افزار آماری SPSS (نسخه 22) و آزمون­های تی مستقل، کای دو، تی زوجی و اندازه­گیری تکراری انجام شد. میزان p کمتر از 05/0 معنادار در نظر گرفته شد.
یافته­ها: در مطالعه بین دو گروه در طول مداخله از نظر میانگین شدت تهوع (01/0=p) و استفراغ (001/0˂p) اختلاف معنی‌داری وجود داشت، ولی از نظر میانگین تعداد دفعات تهوع (08/0=p) و استفراغ (05/0=p) تفاوت معنی‌داری وجود نداشت. نیاز به بستری، داروی اضافی در گروه اندانسترون و طب فشاری K-K9 کمتر و رضایت از درمان بیشتر بود.
نتیجه­گیری: اندانسترون و طب فشاری K-K9 تأثیر بیشتری در کاهش شدت تهوع و استفراغ داشت، لذا توصیه می­شود جهت کاهش تهوع و استفراغ بارداری از اندانسترون و طب فشاری K-K9 استفاده شود.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of ondansetron and K-K9 Acupressure with ondansetron in treatment of nausea and vomiting of pregnancy

نویسندگان [English]

  • Shohreh Kheiri Gharibvand 1
  • Mozhgan Javad Nouri 2
  • Parvaneh Mousavi 1
  • Mohammad Hosein Haghighizadeh 3
1 M.Sc. in Midwifery, Reproductive Health Promotion Research Center, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
2 Ph.D. in Reproductive Health, Reproductive Health Promotion Research Center, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
3 M.Sc. in Biostatistics, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
چکیده [English]

Introduction: Nausea and vomiting in pregnancy is one of the most common problems during pregnancy. Given that there is no research on the use of a combination method of acupressure and antiemetic drugs in reducing nausea and vomiting in pregnancy, therefor, this study was performed with aim to compare the effect of ondansetron and K-K9 Acupressure with ondansetron in nausea and vomiting of pregnancy.
Methods: This randomized clinical trial study was performed in 2018-2019 on 84 pregnant women referred to Ahvaz teaching hospitals. The subjects were randomly divided in two groups of ondansetron with K-K9 acupressure and ondansetron alone. The severity and frequency of nausea and vomiting were recorded by Rhodes questionnaire for 8 days. At days of 1-5 days, both groups received ondansetron tablets 4 mg and in the ondansetron with K-K9 acupressure group in addition to ondansetron tablets, K-K9 acupressure was performed by the research unit. There was no intervention in the two groups on days 6-8. Data were analyzed using SPSS software (version 22) and independent t-test, Chi-square, paired t-test, and repeated measures. P<0.05 was considered statistically significant.
Results: During the intervention, there was significant difference between the two groups in the mean severity of vomiting (P˂0.001) and the mean severity of nausea (P = 0.01), but no significant difference was found between the two groups in the mean number of nausea (P = 0.08) and the mean number of vomiting (P = 0.05). Need to hospitalization and additional drug was less in ondansetron with K-K9 acupressure group, and also satisfaction of treatment was higher.
Conclusions: Ondansetron and K-K9 acupressure is more effective in reducing the severity of nausea and vomiting. Therefore, it is recommended to use ondansetron and K-K9 acupressure to reduce nausea and vomiting during pregnancy.

کلیدواژه‌ها [English]

  • K-K9 Acupressure
  • nausea and vomiting
  • Ondansetron
  • pregnancy
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