مقایسه اثر خوراکی و موضعی زنجبیل بر میزان خونریزی قاعدگی

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دکترای تخصصی طب سنتی، دانشکده طب سنتی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 کارشناس ارشد مامایی، دانشکده مامایی، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران.

3 دانشیار گروه داروسازی سنتی، مرکز تحقیقات طب سنتی و مفردات پزشکی، دانشکده طب سنتی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

4 دانشیار گروه طب سنتی، مؤسسه مطالعات تاریخ پزشکی، طب اسلامی و مکمل، دانشکده طب سنتی، دانشگاه علوم پزشکی ایران، تهران، ایران.

5 استادیار گروه طب سنتی، دانشکده طب سنتی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

چکیده

مقدمه: خونریزی قاعدگی، انعکاسی از ریزش دوره‌ای آندومتر ترشحی در اثر کاهش تولید استرادیول و پروژسترون می‌باشد. در متون طب سنتی زنجبیل به‌عنوان مدر حیض معرفی شده است. مطالعه حاضر با هدف مقایسه اثر خوراکی و موضعی زنجبیل بر میزان خونریزی قاعدگی دختران با قاعدگی منظم انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی تصادفی یک‌‌‌‌سوکور در سال96-1395 بر روی 70 دانشجوی دختر  ساکن در خوابگاه دانشگاه شهید بهشتی انجام شد.  افراد در دو گروه 35 نفره کپسول و روغن زنجبیل قرار گرفتند. هر دو گروه دارو را از 2 روز قبل از شروع قاعدگی تا 3 روز اول قاعدگی برای 3 سیکل قاعدگی متوالی مصرف کردند. چارت هیگام (PBAC) برای تعیین میزان خونریزی قاعدگی استفاده شد. تجزیه و تحلیل داده‌ها با نرم‌افزار آماری SPSS (نسخه 17) و با استفاده از آزمون من ویتنی یو و آزمون فریدمن انجام شد. میزان p کمتر از 05/0 معنادار در نظر گرفته شد.
یافته‌ها: دو گروه در ابتدای مطالعه از نظر حجم خونریزی یکسان بودند (38/0=p).  میانگین حجم خونریزی در سیکل اول در گروه کپسول زنجبیل 01/64±91/104 بود که در سیکل چهارم مداخله به 2/57±76/102 رسید و معنادار نبود (8/0=p) و در گروه روغن زنجبیل میانگین حجم خونریزی در سیکل اول 46/43±8/92 و در سیکل چهارم 14/71±88/101 بود و تفاوت آماری معناداری نداشت (4/0=p).
نتیجه‌گیری: روغن زنجبیل در مقایسه با کپسول زنجبیل در میزان خونریزی قاعدگی در دختران با قاعدگی منظم تفاوتی ندارد و روغن زنجبیل و کپسول زنجبیل هر کدام به تنهایی در میزان خونریزی قاعدگی تأثیری نداشتند.

کلیدواژه‌ها


عنوان مقاله [English]

Comparison of oral and topical effect of ginger on the rate of menstrual bleeding

نویسندگان [English]

  • Pantea Shirooye 1
  • Samira Adhami 2
  • Maryam Hamzeloo-Moghadam 3
  • Fataneh Hashem Dabaghian 4
  • Roshanak Mokaberinejad 5
1 PhD in Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 M.Sc. of Midwifery, School of Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
3 Associate Professor, Department of Traditional Pharmacy, Traditional Medicine and Materia Medica Research Center, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Associate Professor, Department of Traditional Medicine, Research Institute for Islamic and Complementary Medicine, School of Traditional Medicine, Iran University of Medical Sciences, Tehran, Iran.
5 Assistant Professor, Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Menstrual bleeding is a reflection of periodic secretion endometrial loss due to decreased estradiol and progesterone production. In traditional medicine, ginger is described as a menstrual blood enhancer. This study was performed with aim to compare the oral and topical effect of ginger on the rate of menstrual bleeding in girls with regular menstruation.
Methods: This single-blind randomized clinical trial study was performed on 70 female students living in the dormitory of Shahid Beheshti University in 2016-2017. Subjects were divided into two groups: capsules and ginger oil (n=35 in each group). Both groups consumed the drug for three consecutive menstrual cycles from two days before menstruation until the first three days of menstruation. The Higham chart (PBAC) was used to determine the amount of menstrual bleeding. Data were analyzed by SPSS software (version 17) using Mann-Whitney U and Friedman tests. P< 0.05 was considered statistically significant.
Results: The two groups were similar in terms of bleeding volume at the beginning of the study (P=0.38). The mean volume of bleeding in the first cycle in the ginger capsule group was 104.91 ± 64.01, and reached to 102.26 ± 57.2 in the fourth cycle of intervention, which was not significant (p= 0.8). In the ginger oil group, the mean volume of bleeding in the first cycle was 92.8 ± 46.44 and in the fourth cycle 101.88 ± 71.14, which was not significant (p= 0.4).
Conclusion: Ginger oil was not different from ginger capsules in the amount of menstrual bleeding in girls with regular menstruation; ginger oil and ginger capsule alone did not affect menstrual bleeding.

کلیدواژه‌ها [English]

  • Ginger capsule
  • Ginger oil
  • Persian Medicine
  • Regular menstruation
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