تظاهرات بالینی، پیامدهای مادری، جنینی و نوزادی زنان باردار مبتلا به کووید-19، یک مطالعه مرور سیستماتیک

نوع مقاله : مروری

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، کارگروه دانشجویی مرکز تحقیقات توسعه اجتماعی و ارتقاء سلامت، دانشکده پزشکی، دانشگاه علوم پزشکی گناباد، گناباد، ایران.

2 دانشجوی کارشناسی تغذیه، کمیته تحقیقات دانشجویی، دانشکده پزشکی، دانشگاه علوم پزشکی زاهدان، زاهدان، ایران.

3 استادیار گروه مامایی، مرکز تحقیقات توسعه اجتماعی و ارتقاء سلامت، دانشکده پزشکی، دانشگاه علوم پزشکی گناباد، گناباد، ایران.

چکیده

مقدمه: ویروس کرونا به یک همه‌گیری در سراسر جهان تبدیل شده است و قابلیت گسترش سریع دارد. زنان باردار و نوزادانشان به‌علت ضعف سیستم ایمنی، آسیب‌پذیرتر هستند. مطالعه حاضر با هدف مرور تظاهرات بالینی، پیامدهای مادری، جنینی و نوزادی در زنان باردار مبتلا به کووید-19 انجام شد.
روشکار: در این مطالعه مروری جهت یافتن مقالات مرتبط، پایگاه­های scopus، pubmed، medrxiv وWeb of science از ابتدای 2019 تا 30 ژانویه 2021 با استفاده از کلیدواژه­های فارسی ویروس کرونا، پیامدهای بارداری با همه ترکیبات احتمالی و معادل انگلیسی آنها (corona virus، pregnancy outcomes) با استفاده از عملگرهای AND، OR و NOT مورد جستجو قرار گرفتند. بر اساس معیار استروب، مطالعاتی که در ارزیابی کیفیت بالا و متوسط را اخذ نمودند، وارد مطالعه و بررسی شدند.
یافتهها: از مجموع 3771 مطالعه، 17 مطالعه وارد این مطالعه مروری شدند که 4494 زن باردار کرونا مثبت در 9 کشور مختلف را شامل می­شد. علامت شایع در مادران باردار، تب و سرفه بود و عارضه نوزادی این ویروس شامل زایمان زودرس و دیسترس تنفسی بود. اکثر زایمان­ها به روش سزارین بود و اکثر بیماران از آنتی‌بیوتیک و دارو­های ضدویروسی برای درمان استفاده کردند. شواهد زیادی از انتقال عمودی کووید-19 از طریق زایمان واژینال حمایت نکرد. شایع‌ترین تست تشخیصی بیماری کووید-19 PCR بود.
نتیجهگیری: در اکثر مطالعات افزایش انجام زایمان به‌روش سزارین به‌دنبال بروز دسترس جنینی بود، اما به‌دلیل آسیب‌پذیری این دو گروه، اقدامات پیشگیری و مراقبتی باید در نظر گرفته شود و بر آموزش افراد تأکید بیشتری صورت گیرد.

کلیدواژه‌ها


عنوان مقاله [English]

Clinical manifestations, maternal, fetal and neonatal outcomes in pregnant women with COVID- 19: A systematic review

نویسندگان [English]

  • Masuomeh Fayazi 1
  • Rasoul Rahmani 2
  • Roghaieh Rahmani Bilandi 3
1 M.Sc. student of Midwifery, Student Research Committee of Social Development and Health Promotion Research Center, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
2 B.Sc. Student of Nutrition, Student Research Committee, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
3 Assistant Professor, Department of Midwifery, Social Development and Health Promotion Research Center, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
چکیده [English]

Introduction: Coronavirus has become a worldwide epidemic and can spread rapidly. Pregnant women and infants are more vulnerable due to weak immune systems. This study was performed with aim to review the clinical manifestations, maternal, fetal, and neonatal outcomes in pregnant women with COVID-19.
Methods: In this review study, to find the related studies, databases of Pubmed, Scopus, Medrxiv, and Web of Science were searched from the first of 2019 until January 30, 2021 using the keywords of Corona virus, pregnancy outcomes with all possible combinations and their English equivalents. Boolean operators (AND, NOT, OR) were used to search the databases. According to Strobe criteria, the studies which received high and medium quality evaluation were included in the study and reviewed.
Results: Out a total of 3771 studies, 17 were included in this review. 4494 pregnant women were corona positive in 9 different countries. The most common symptoms of corona virus in mothers were fever and cough, and the neonatal complication of the virus included preterm delivery and respiratory distress. Most deliveries were by cesarean section and most patients used antibiotics and antiviral drugs for treatment. There was not much evidence to support the vertical transmission of Covid-19 through vaginal delivery. The most common diagnostic test for Covid-19 disease was PCR.
Conclusion: In most studies, the increase in cesarean delivery was due to fetal distress. However, due to the vulnerability of these two groups, preventive and precautionary measures should be considered and more emphasis should be done on educating people.

کلیدواژه‌ها [English]

  • Coronavirus
  • Infants
  • pregnancy
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