بررسی نقش داروهای گیاهی در درمان سندرم تخمدان پلی‌کیستیک در مطالعات حیوانی: یک مطالعه مروری نقلی

نوع مقاله : مروری

نویسندگان

1 استادیار گروه مامایی و بهداشت باروری، مرکز تحقیقات مراقبت‌های پرستاری و مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران.

2 کارشناس ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه آزاد کرمان، کرمان، ایران.

3 استادیار گروه مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی نیشابور، نیشابور، ایران.

4 مربی گروه مامایی، مرکز تحقیقات اجتماعی و ارتقاء سلامت، دانشکده پزشکی، دانشگاه علوم پزشکی گناباد، گناباد، ایران.

5 دانشجوی دکترای تخصصی بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران. کارشناس ارشد گروه مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی یزد، یزد، ایران.

6 دانشجوی دکترای تخصصی بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران.

چکیده

مقدمه: سندرم تخمدان پلی‏‏کیستیک شایع‏ترین اختلال غدد درون‌ریز میان زنان در سنین باروری و شایع‏ترین علت ناباروری ناشی از عدم تخمک‌گذاری است. جهت درمان عوارض ناشی از این بیماری طیف گسترده‌ای از داروهای شیمیایی تجویز می‌شود. امروزه به‌دلیل اثربخشی داروهای گیاهی در کنار عوارض کم آنها، تمایل به استفاده از داروهای گیاهی افزایش یافته است. بدین‌منظور مطالعه مروری حاضر با هدف تعیین نقش داروهای گیاهی در سندرم تخمدان پلی‌کیستیک در مطالعات حیوانی انجام شد.
روش‌کار: در این مطالعه مروری پایگاه­های اطلاعاتی Science direct، Google Scholar، Web of science، EMBASE،Pubmed ، Scopus و ProQuest با استفاده از کلیدواژه­های فارسی سندرم تخمدان پلی‌کیستیک، گیاهان دارویی، بررسی سیستماتیک، طب سنتی، کارآزمایی بالینی، کنترل موردی، ناباروری زنان و معادل انگلیسی آنها در بازه زمانی 2020-1990 مورد جستجو قرار گرفتند. در ابتدا 875 مقاله یافت شد که در نهایت 38 مقاله که مطابق با اهداف مطالعه بودند، به‌طور کامل بررسی و از این میان 14 مقاله­ مرتبط وارد مطالعه شدند و مورد نقد و بررسی قرار گرفتند.
یافته‌ها: بر اساس نتایج مورد بررسی، داروهای گیاهی متعددی از جمله گیاه پنج‌انگشت، رازیانه، زیره سیاه، کاسنی، شیرین‌بیان، صبر زرد، چای کوهی، چای سبز، هسته انگور، سیاه‌دانه و کالیگونوم کوموسوم می‌توانند در درمان بسیاری از مشکلات ایجاد شده به‌دلیل سندرم تخمدان پلی‌کیستیک مؤثر باشند.
نتیجه‌گیری: استفاده از گیاهان دارویی با خاصیت آنتی‌اکسیدانی، ضدالتهابی و تعادل هورمونی می‌توانند به‌عنوان جانشین یا مکمل داروهای شیمیایی مؤثر بر سندرم تخمدان پلی‌کیستیک مورد استفاده قرار گیرند و یک عامل اصلی در درمان یا کاهش عوارض از بیماری سندرم تخمدان پلی‌کیستیک باشند.

کلیدواژه‌ها


عنوان مقاله [English]

The role of herbal medicines in the treatment of polycystic ovary syndrome in animal studies: A narrative review study

نویسندگان [English]

  • Mitrai Savabi Esfahan 1
  • Hadiseh Safinezhad 2
  • Mahboubeh Gholami 3
  • Fatemeh Shaghaghi 4
  • Leila Asadi 5
  • Zahra Mohebi Dehnavi 6
1 Assistant professor, Department of Midwifery and Reproductive Health, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.
2 M.Sc. of Midwifery, School of Nursing and Midwifery, Kerman Azad University, Kerman, Iran.
3 Assistant professor, Department of Midwifery, School of Nursing and Midwifery, Neyshabour University of Medical Sciences, Neyshabour, Iran.
4 Instructor, Department of Midwifery, Social Research and Health Promotion Research Center, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
5 PhD student in Reproductive Health, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran. M.Sc. of Midwifery and Reproductive Health, School of Nursing and Midwifery, Yazd University of Medical Sciences, Yazd, Iran.
6 PhD student in Reproductive Health, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.
چکیده [English]

Introduction: Polycystic ovary syndrome is the most common endocrine disorder among women of childbearing age and the most common cause of infertility due to anovulation. To treat the side effects of this disease, a wide range of chemical drugs are prescribed. Today, due to the effectiveness of herbal medicines and their low side effects, the tendency to use herbal medicines has increased. This study was performed with aim to determine the role of herbal medicines in polycystic ovary syndrome in animal studies.
Methods: In this review study, the databases of Web of Science, Google Scholar, ScienceDirect, Scopus, PubMed, ProQuest, and EMBASE were searched using Persian and English keywords of polycystic ovary syndrome, medicinal herbs, systematic review, traditional medicine, clinical trial, case control, and female infertility in the period of 1990-2020. Initially, 875 articles were found, and finally, 38 articles which were in accordance with the objectives of the study were fully evaluated, and among them, 14 related articles were included in the study, and were reviewed.
Results: According to the results, several herbal medicines such as five-fingered plant, fennel, black cumin, chicory, licorice, yellow aloe, mountain tea, green tea, grape seed, black seed, and Caligum comosum can be effective in treatment of many problems caused by polycystic ovary syndrome.
Conclusion: The use of medicinal herbs with antioxidant, anti-inflammatory and hormonal balance can be used as a substitute or supplement for chemical drugs effective in polycystic ovary syndrome and a major factor in the treatment or reduction of complications of polycystic ovary syndrome.

کلیدواژه‌ها [English]

  • Herbal medicines
  • Polycystic ovary syndrome
  • Traditional Medicine
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