بررسی یک مورد فیلودیس تومور بزرگ به‌دنبال مصرف رازیانه: گزارش یک مورد نادر

نوع مقاله : گزارش مورد

نویسندگان

1 مربی گروه بیهوشی، مرکز تحقیقات مؤلفه‌های اجتماعی نظام سلامت، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

2 کارشناس بهداشت، مرکز تحقیقات سلامت و بیماری‌های زنان، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

3 استادیار گروه جراحی، مرکز تحقیقات سلامت و بیماری‌های زنان، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران.

چکیده

مقدمه: تومورهای فیلودس (PTs)، نئوپلاسم‌های فیبروئپیتلیال پستان هستند.  PT‌ها نسبتاً نادر هستند و کمتر از 1% از کل نئوپلاسم‌های پستان را تشکیل می‌دهند. در این مطالعه یک مورد فیلودیس تومور بزرگ به‌دنبال مصرف رازیانه گزارش می‌شود.
معرفی بیمار: بیمار خانمی 47 ساله MCzabz بود که با شکایت توده بزرگ در پستان چپ به بیمارستان پیمانیه شهرستان جهرم مراجعه کرد. بیمار به‌ مدت 8 سال سابقه نازایی داشته و از 2 سال قبل توده‌ای به ابعاد 3 سانتی‌متر در پستان چپ داشته است و طی 7 ماه قبل، به‌مدت 3 ماه به‌دلیل بی‌نظمی قاعدگی، رازیانه مصرف کرده است.
نتیجه‌گیری: به‌نظر می‌رسد افزایش سایز تومور پستان در این بیمار به‌دلیل مصرف خودسرانه رازیانه باشد، زیرا رازیانه استروژن زیادی دارد که بر سلول‌های دارای گیرنده‌های استروژنی بتا تأثیر می‌گذارد و سلول‌های فیلودس تومور نیز دارای گیرنده‌های استروژنی بتا  می‌باشند که در این بیمار به‌دلیل مصرف خودسرانه رازیانه به‌مدت 3 ماه، باعث افزایش حجم ناگهانی این توده در پستان بیمار شده است.

کلیدواژه‌ها

عنوان مقاله [English]

A large Phyllodes tumor following fennel consumption: Report of a rare case

نویسندگان [English]

  • Navid Kalani 1
  • Elham Rafei 2
  • Marzieh Haghbeen 3
1 Instructor, Department of Anesthesiology, Clinical Research Development Unit of Peymanieh Hospital, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
2 B.Sc. in Health, Women’s Health and Diseases Research Center, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
3 Assistant Professor, Department of Surgery, Women’s Health and Diseases Research Center, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.
چکیده [English]

Introduction: Phyllodes (PTs) tumors are fibroblastic neoplasms of the breast. PTs are relatively rare and include less than 1% of all breast neoplasms. In this study, a case of large tumor of Phyllodes following fennel consumption was reported.
Case presentation: The patient was a 47-year-old MCzabz female who complained of a large mass in the left breast and referred to Peymaniyeh Hospital in Jahrom. The patient had a history of infertility for 8 years. She had a 3 cm mass in the left breast from the past 2 years. During previous 7 months, she has used fennel for 3 months due to menstrual irregularities.
Conclusion: It seems that the increasing of the breast tumor size in this patient is due to arbitrary consumption of fennel; because fennel has a lot of estrogen, which affects Endoplasmic Reticulum, and tumor filament cells also have beta ER-estrogen receptors; in this patient, the arbitrary consumption of fennel for 3 months has led to the sudden increase in the volume of this mass in the breast.

کلیدواژه‌ها [English]

  • Breast
  • Fennel
  • Phyllodes Tumors

مراجع

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مجله زنان، مامایی و نازایی ایران
دوره 24، شماره 3
خرداد 1400
صفحه 101-106

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