تأثیر شش هفته تمرینات تناوبی با شدت بالا بر سطوح سرمی استئوکلسین غیرکربوکسیله، مقاومت به انسولین و نیمرخ لیپیدی دختران دارای اضافه وزن: کارآزمایی بالینی تصادفی شده

نوع مقاله : اصیل پژوهشی

نویسندگان

1 کارشناس ارشد گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه شهید چمران اهواز، اهواز، ایران.

2 دانشیار گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه شهید چمران اهواز، اهواز، ایران.

3 استادیار گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه شهید چمران اهواز، اهواز، ایران.

چکیده

مقدمه: فعالیت ‌بدنی و ورزش از طریق سازوکارهای گوناکونی می‌تواند موجب ارتقای سلامتی در افراد گردد. بافت استخوان بدن می‌تواند تحت تأثیر فعالیت بدنی و ورزش متابولیسم گلوکز و چربی را تغییر دهد. بنابراین مطالعه حاضر با هدف بررسی تأثیر تمرینات تناوبی با شدت بالا (HIIT) بر سطوح سرمی استئوکلسین غیرکربوکسیله، مقاومت به انسولین و نیمرخ لیپیدی دختران دارای اضافه‌وزن انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی شاهددار تصادفی شده در سال 1399 بر روی 24 نفر از دانشجویان دختر دارای اضافه‌وزن (شاخص توده بدنی 38/2±58/28) در دانشگاه شهید چمران اهواز انجام شد. افراد ‌به‌طور تصادفی به دو گروه تمرین 12 نفره HIIT و کنترل تقسیم شدند. گروه تمرین به‌مدت 6 هفته (3 جلسه در هفته) به تمرین پرداختند، در حالی‌که گروه کنترل هیچ فعالیت بدنی منظمی نداشتند. نمونه‌های خونی جهت اندازه‌گیری سطوح سرمی استئوکلسین، انسولین، گلوکز و نیمرخ لیپیدی (48 ساعت قبل و پس از دوره مداخله) گرفته شد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار SPSS (نسخه23) و آزمون‌های تی زوجی و تی مستقل انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: اجرای6 هفته تمرین‌ تناوبی با شدت بالا منجر به افزایش سطوح ‌سرمی استئوکلسین‌ غیرکربوکسیله (045/0=p) و کاهش معنی‌دار گلوکز (026/0=p)، مقاومت ‌به ‌انسولین (036/0=p)، تری‌گلیسیرید (017/0=p) و LDL (04/0=p) گردید. درحالی‌که در سایر اجزای نیمرخ لیپیدی (کلسترول تام و HDL) تغییرات معنی‌داری مشاهده نشد (05/0≤p).
نتیجه‌گیری: اجرای تمرینات تناوبی با شدت بالا منجر به بهبود معنی‌دار مقاومت به انسولین و برخی از شاخص‌های نیمرخ لیپیدی (تری‌گلیسیرید و LDL) گردید که ممکن است ناشی از افزایش شاخص عملکرد آندوکرینی استخوان (استئوکلسین غیرکربوکسیله) باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of six weeks of high intensity interval training on under-Carboxylated Osteocalcin serum levels, insulin resistance, and lipid profile in overweight girls: randomized clinical trial

نویسندگان [English]

  • Fatemeh Fakhri 1
  • Somaye Fakhri 1
  • Saeed Shakeryan 2
  • Aliakbar Alizadeh 3
1 M.Sc. of Exercise Physiology, School of Sport Sciences, Shahid Chamran Universityof Ahvaz, Ahvaz, Iran.
2 Associate Professor, Department of Exercise Physiology, School of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
3 Assistant Professor, Department of Exercise Physiology, School of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
چکیده [English]

Introduction: Physical activity and exercise through different mechanisms can promote health in individuals.The body's bone tissue can alter glucose and fat metabolism under the influence of physical activity and exercise. Therefore, this study was performed with aim to investigate the effect of high intensity interval training (HIIT) on serum levels of under-carboxylated osteocalcin, insulin resistance and lipid profile in overweight girls.
Methods: This randomized controlled clinical trial study was performed on 24 overweight female students (body mass index: 28.58±2.38) in Shahid Chamran University of Ahvaz in 2020. The subjects were randomly divided into two groups of 12-member: HIIT and control. The training group practiced for 6 weeks (3 sessions per week), while the control group did not have any regular physical activity. Blood samples were obtained for measurement of serum level of Osteocalcin, glucose, insulin and lipid profile (48 hours before and after the intervention period). Data were analyzed by SPSS software (version 23) and paired-t and independent t-test. P<0.05 was considered statistically significant.
Results: Performing high intensity interval training for 6 weeks led to an increase in serum levels of under-carboxylated osteocalcin (P=0.045), significant decrease in glucose (P=0.026), insulin resistance (P=0.036), triglycerides (P=0.017) and LDL (P=0.04) in overweight girls; while, no significant changes were observed in other components of lipid profile (total cholesterol and HDL) (P≥0.05).
Conclusion: Performing high intensity interval training led to a significant improvement in insulin resistance and some features of the lipid profile (triglycerides and LDL). This may be due to an increase in the endocrine function of the bone (under-carboxylated osteocellin).

کلیدواژه‌ها [English]

  • High Intensity Interval Training
  • insulin resistance
  • lipid profile
  • Overweight
  • under-carboxylated osteocalcin
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