بررسی پیامد نوزادی پره اکلامپسی در زنان باردار با و بدون ابتلاء به دیابت حاملگی همراه با سندرم تخمدان پلی‌کیستیک

نوع مقاله : اصیل پژوهشی

نویسندگان

1 کارشناس ارشد پرستاری، دانشکده علوم پزشکی شوشتر، شوشتر، ایران.

2 کارشناس ارشد آمار زیستی، دانشکده علوم پزشکی شوشتر، شوشتر، ایران.

3 دانشجوی کارشناسی مامایی، کمیته تحقیقات دانشجویی، دانشکده علوم پزشکی شوشتر، شوشتر، ایران.

چکیده

ﻣﻘﺪﻣﻪ: دﻳﺎبت بارداری، ﺷﺎﻳﻊ‌ﺗﺮﻳﻦ اﺧﺘﻼل ﻣﺘﺎﺑﻮﻟﻴﻚ و PCO از مهم‌ترین علل ناباروری در دوران بارداری اﺳﺖ ﻛﻪ به همراه پره‌اکلامپسی با عوارض متعددی برای مادر و جنین همراه هستند. با توجه به عوارض این اختلالات، مطالعه حاضر با هدف تعیین تأثیر پیامد پره‌اکلامپسی در زنان مبتلا به دیابت بارداری و سندرم تخمدان پلی‌کیستیک در بیمارستان الهادی شوشتر انجام شد.
روش‌ﻛﺎر: این مطالعه مورد- شاهدی بر روی 152 زن باردار مبتلا به پره‌اکلامپسی که طی سال‌های 96-1395 در بخش زایمان بیمارستان الهادی شهرستان شوشتر بستری بودند، انجام شد. افراد بر اساس ابتلاء یا عدم ابتلاء به دیابت حاملگی همراه با PCO به دو گروه 76 نفره مورد و شاهد تقسیم شدند. داده‌های مربوط به هدف مطالعه از پرونده بیماران استخراج و در پرسشنامه ثبت گردید. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 16) و آزمون‌های کولموگروف- اسمیرنوف، تی مستقل، آزمون کای دو انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: بر اساس نتایج مطالعه، بین دو گروه مورد و شاهد از نظر سابقه PCO، سابقه نازایی، سابقه دیابت بارداری، سابقه پره‌اکلامپسی و شاخص توده بدنی تفاوت معناداری وجود داشت (001/0p<). از بین عوارض نوزادی، کاهش رشد داخل رحمی بین گروه‌ها تفاوت معناداری داشت (03/0=‌p)؛ به‌طوری‌که نسبت ابتلاء نوزادان به کاهش رشد داخل رحم در گروه مورد 1/2 برابر گروه شاهد بود (46/2-76/1: CI، 2/1=OR)، اما بین تعداد سقط، تعداد بارداری، آپگار و وزن نوزاد و بستری در NICU تفاوت معناداری بین دو گروه وجود نداشت (05/0‌<p).
ﻧﺘﻴﺠﻪ‌ﮔﻴﺮی: دیابت بارداری و سندرم تخمدان پلی‌کیستیک در حضور پره اکلامپسی به‌طور معناداری با کاهش رشد داخل رحمی نوزادان همراه است.

کلیدواژه‌ها

عنوان مقاله [English]

Preeclampsia Neonatal Outcome in Pregnant Women with and without Gestational Diabetes Mellitus and Polycystic Ovary Syndrome

نویسندگان [English]

  • Akram Hemmatipur 1
  • Azam Jahangiri Mehr 2
  • Elham Touriaie 3
  • Masoumeh Salehi Kombu 1
1 M.Sc. in Nursing, Shoushtar School of Medical Sciences, Shoushtar, Iran.
2 M.Sc. in Biostatistics, Shoushtar School of Medical Sciences, Shoushtar, Iran.
3 B.Sc. Student of Midwifery, Student Research Committee, Shoushtar School of Medical Sciences, Shoushtar, Iran.
چکیده [English]

Introduction: Gestational diabetes mellitus is the most common metabolic disorder. Polycystic ovary syndrome (PCO) is one of the most important causes of infertility during the fertility period, resulting in preeclampsia and many maternal and fetal complications.
Methods: This case-control study was conducted on 152 pregnant women with preeclampsia admitted to the Maternity Ward of Shoushtar Al-Hadi Hospital in 2016-2017. The study population was assigned of case (n=76) and control (n=76) based on infliction with gestational diabetes mellitus and PCO. Data analysis was performed in SPSS (version 16) using Kolmogorov–Smirnov test, independent t-test, and Chi-square test. P-value less than 0.05 was considered statistically significant.
Results: The mean ages of the mothers and pregnancy termination were 31±6 years and 34±5.02 months, respectively. There was a statistically significant difference between the two groups in terms of the history of PCO, infertility, gestational diabetes, and preeclampsia, as well as, body mass index (P<0.001). Among the neonatal complications, the two groups were significantly different regarding the decreased intrauterine growth (P=0.03). In this regard, the ratio of decreased intrauterine growth was 2.1 times higher in the case group, compared to that in the control group (OR: -1.2, CI: 1.76-2.46).
Conclusion: Gestational diabetes mellitus and polycystic ovarian syndrome in the presence of preeclampsia are associated with a significant reduction in fetal intrauterine growth.

کلیدواژه‌ها [English]

  • Polycystic ovary syndrome
  • Gestational Diabetes Mellitus
  • Preeclampsia
  • Neonatal complications

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مجله زنان، مامایی و نازایی ایران
دوره 21، شماره 5
مرداد 1397
صفحه 47-57

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