عنوان مقاله [English]
Introduction: Cryopreserved-embryo transfer is one of the most important treatments for infertile couples. While fresh-embryo transfer is mostly approved and concerned, few studies have evaluated the potential effect of clinical factor on the implantation and pregnancy rates in frozen embryo transfer. The aim of this study was to investigate some clinical factors that potentially influence the outcome of cryopreserved-embryo transfer.
Methods: In this retrospective investigation, 372 patients' records that referred to Research and Clinical Center of Infertility and had frozen-embryo transfer cycles were studied from 2009 to 2011. All data of patient`s files fill in the questionnaire form. Data were analyzed by SPSS software version 15 and Kolmogorov-Smirnov, Paired t and t student tests. P value less than 0.05 was considered statistically significant.
Results: Clinical pregnancy-rate in patients under 35 years old was significantly higher than patients aged more than 35 years old (57.7% versus 29.2%). Also, clinical pregnancy-rate in women with FSH more and less than 10 IU/L were 56.3% and 17.5%, respectively (PV=0.0001) which were statistically significant. Other clinical factors such as: the causes of embryo freezing, primary protocols of IVF /ICSI, endometrial thickness and duration of cycle up to day of embryo transfer had no significant effects on frozen-embryo transfer (P>0.05).
Conclusion: Age of women and FSH in third day were the most important factors influencing the clinical pregnancy rate following frozen embryo transfer.