بررسی تأثیر فرآورده موضعی حاوی عصاره توت روباهی در بهبود زخم اپی‌زیاتومی در زنان نخست‌زا: کارآزمایی بالینی سه‌سوکور

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، گروه مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 استادیار گروه مامایی و بهداشت باروری، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 استادیار گروه آمار زیستی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

4 استاد گروه فارماکوگنوزی، مرکز تحقیقات علوم دارویی، دانشکده داروسازی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

5 استادیار گروه زنان و زایمان، دانشکده پزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران

10.22038/ijogi.2025.90006.6509

چکیده

مقدمه: یکی از مداخلات پزشکی در زایمان، اپی‌زیاتومی می‌باشد که برای وسیع‌تر کردن دهانه خروجی لگن به‌کار می‌رود. درد ناشی از اپی‌زیاتومی، کیفیت زندگی مادر را تحت تأثیر قرار می‌دهد. گیاه توت‌روباهی با وجود ترکیباتی همچون اسیدلینولئیک، اسیدلینولنیک، فلاونوئیدها، تانن‌ها و سطوح بالایی از بتاکاروتن، ویتامین E و C و سایر آنتی‌اکسیدان، دارای اثرات ضد التهابی، ضد احتقان، فعالیت ضد درد با پتانسیل ضدباکتریایی می‌باشد که می‌تواند در روند بهبود زخم مؤثر باشد. مطالعه حاضر با هدف تأثیر فرآورده موضعی حاوی عصاره توت روباهی در بهبود زخم اپی‌زیاتومی در زنان نخست‌زا انجام شد.
روش‌کار: این پژوهش کارآزمایی بالینی تصادفی شده همراه با گروه کنترل سه‌سوکور در سال 1403 بر روی 86 زن نخست‌زای مراجعه‌کننده به بیمارستان مهدیه شهر تهران انجام گرفت. پس از زایمان، به‌مدت 10 روز و هر روز 2 بار از پماد حاوی عصاره توت روباهی جهت استعمال موضعی بر روی برش اپی‌زیاتومی تجویز شد. ابزار گردآوری داده‌ها شامل پرسشنامه اطلاعات دموگرافیک و مامایی، مقیاس دیداری درد، چک‌لیست ریدا و پرسشنامه بررسی عوارض و رضایت‌مندی از مداخله بود. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 26) و آزمون‌های آماری کای اسکوئر، تی‌مستقل، بونفرونی و من ویتنی یو انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته­ ها: هر دو گروه گیاه توت‌روباهی و دارونما از نظر ویژگی‌های دموگرافیک و مامایی قبل از مداخله اختلاف آماری معناداری نداشتند (05/0˃p). نمره بهبود زخم در دو گروه قبل از مداخله اختلاف آماری معناداری نداشت (648/0=p). میانگین نمره بهبود زخم در گروه توت‌روباهی در روز پنجم و دهم در مقایسه با گروه دارونما اختلاف آماری معناداری داشت (001/0˂p).
نتیجه ­گیری: پماد حاوی عصاره گیاه توت‌روباهی باعث کاهش درد و بهبود زخم اپی‌زیاتومی در زنان نخست‌زا می‌گردد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effect of Topical Product Containing Sanguisorba Minor Extract on Episiotomy Wound Healing in Primiparous Women: A Triple-Blind Clinical Trial

نویسندگان [English]

  • Rogheyeh Ahmadi 1
  • Mahbobeh Ahmadi Doulabi 2
  • Malihe Nasiri 3
  • Faraz Mojab 4
  • Nayyereh Rahmati 5
1 M.Sc. Student of Midwifery, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Assistant Professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Assistant Professor, Department of Biostatistics, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Professor, Department of Pharmacognosy, Pharmaceutical Sciences Research Center, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: One of the medical interventions in childbirth is episiotomy which is used to widen the pelvic outlet. The pain resulting from episiotomy affects mother's quality of life. Foxberry plant, with its compounds such as linoleic acid, linolenic acid, flavonoids, tannins, and high levels of beta-carotene, vitamins E and C, and other antioxidants, has anti-inflammatory, anti-congestive, analgesic, and antibacterial potential effects that can be effective in the wound healing process. The present study was conducted with aim to evaluate the effect of topical product containing Sanguisorba minor extract on episiotomy wound healing in primiparous women.
Methods: This randomized triple-blind controlled clinical trial was conducted in 2024 on 86 primiparous women referred to Mahdieh Hospital in Tehran. After delivery, 2 gr of ointment containing Sanguisorba minor was prescribed for topical application on the episiotomy incision twice a day for 10 nights for both groups. Data collection tools included demographic and obstetric information questionnaire, visual pain scale, Rida checklist, and questionnaire to assess complications and satisfaction with the intervention. Data analysis was performed using SPSS software (version 26) and chi-square, independent t-test, Bonferroni, and Mann-Whitney U tests. P<0.05 was considered significant.
Results: There was no statistically significant difference between the Sanguisorba minor and placebo groups in terms of demographic and obstetric characteristics before the intervention (P˃0.05). There was no statistically significant difference in the wound healing score in the two groups before the intervention (P=0.648). The mean wound healing score in the Sanguisorba minor group on the fifth and tenth days was significantly different compared to the placebo group (P˂0.001).
Conclusion: Ointment containing Sanguisorba minor extract reduces pain and improves episiotomy wounds in primiparous women.

کلیدواژه‌ها [English]

  • Episiotomy
  • Sanguisorba Minor
  • Wound Healing

مراجع

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مجله زنان، مامایی و نازایی ایران
دوره 28، شماره 10
دی 1404
صفحه 49-61

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