بررسی تأثیر پماد حاوی روغن جوجوبا بر شدت درد زخم اپی‌زیاتومی در زنان نخست‌زا: کارآزمایی بالینی تصادفی سه‌سوکور

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 استاد گروه مامایی و بهداشت باروری، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 استاد گروه فارماکوگنوزی، مرکز تحقیقات علوم دارویی، دانشکده داروسازی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

4 دانشیار گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

5 کارشناس ارشد سلامت و رفاه اجتماعی، مرکز تحقیقات عوامل اجتماعی مؤثر بر سلامت، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

10.22038/ijogi.2025.84737.6297

چکیده

 مقدمه: برش اپی‌زیاتومی به‌منظور تسهیل خروج جنین در ناحیه پرینه اعمال می‌شود و ممکن است دچار عوارضی مانند درد و التهاب شود. جوجوبا به‌دلیل دارا بودن فلاونوئیدها و ترکیبات فنولی، به واسطه اثر بر روی گیرنده های گابا آمینوبوتریک اسید و مهار آنزیم­ های درگیر در مغز، درد را به‌صورت مرکزی کنترل می‌کند. مطالعه حاضر با هدف تعیین تأثیر پماد حاوی روغن جوجوبا بر شدت درد زخم اپی‌زیاتومی در زنان نخست‌زا انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی تصادفی سه‌سوکور در سال 1403 بر روی 92 زن نخست‌زای مراجعه کننده به بیمارستان مهدیه تهران انجام گرفت. 46 نفر در گروه مداخله و 46 نفر در گروه دارونما قرار گرفتند. پس از زایمان، به‌مدّت 10 روز، هر 12 ساعت یک‌بار، پماد جهت استعمال موضعی بر روی ناحیه برش برای هر دو گروه مطالعه تجویز شد. ابزارهای گردآوری داده‌ها شامل: پرسشنامه دموگرافیک، چک‌لیست مشخصات مامایی و زنان، فرم وضعیت بهداشتی و مقیاس عددی دیداری سنجش درد بود. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 21) و آزمون­ های کای اسکوئر، تی مستقل، دقیق فیشر و آزمون واریانس دوعاملی انجام شد. میزان p کمتر از 05/0 معنادار در نظر گرفته شد.
یافته ­ها: بین استفاده از پماد حاوی روغن جوجوبا و درد به‌طور کلی در 3 حالت اندازه‌گیری تفاوت آماری معناداری وجود داشت (001/0p<) و 1/71% از تغییرات ایجاد شده در متغیر درد به‌دلیل استفاده از پماد حاوی روغن جوجوبا بوده است. در مقایسه میانگین بهبودی زخم در سه مرحله، روند کاهش درد در گروه مداخله در روز 5 بعد از زایمان و روز 10 بعد از زایمان بیشتر از گروه کنترل بود (001/0=p).
نتیجه­ گیری: پماد حاوی روغن جوجوبا سبب تقلیل شدت درد ناشی از برش اپی­ زیاتومی در زنان نخست‌زا می­ شود.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of ointment containing jojoba oil on pain intensity of episiotomy wound in primiparous women: A triple-blind clinical trial

نویسندگان [English]

  • Kimia Hosseinpour 1
  • Mahrokh Dolatian 2
  • Faraz Mojab 3
  • Zahra Naeiji 4
  • Farima Mohamadi 5
1 M.Sc. Student of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Professor, Department of Pharmacognosy, Pharmaceutical Sciences Research Center, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5 M.Sc. of Health and Social Welfare, Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Episiotomy is performed in the perineum to facilitate delivery of the fetus and may cause complications such as pain and inflammation. Jojoba due to its flavonoids and phenolic compounds controls pain centrally by acting on GABA receptors and inhibiting enzymes involved in the brain. The present study was conducted with aim to determine the effect of ointment containing jojoba oil on pain intensity of episiotomy wound in primiparous women.
Methods: This triple-blind cllinical trial was conducted in 2024 on 92 primiparous women referred to Mahdieh Hospital, Tehran (46 in the intervention group and 46 in the placebo group). After delivery, for 10 days, every 12 hours, ointment for local use on the incision area was prescribed for both study groups. Data collection tools include demographic questionnaire, obstetrics and gynecology information checklist, health status form and visual analog scale. Data analysis was done using SPSS statistical software (version 21)  and chi-square, independent t, Fisher's exact and two-way ANOVA. P<0.05 was considered significant.
Results: There was a statistically significant difference between the use of ointment containing jojoba oil and pain in general in 3 measurement modes (p<0.001), and 71.1% of the changes made in the pain variable was due to the use of ointment containing jojoba oil. Comparing the mean wound healing in three stages showed that the trend of pain reduction in the intervention group on the 5th day after delivery and the 10th day after delivery was more than the control group (p=0.001).
Conclusion: Ointment containing jojoba oil reduces the intensity of pain caused by episiotomy in primiparous women.

کلیدواژه‌ها [English]

  • Episiotomy
  • Jojoba plant
  • Pain
  • Primiparous women

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مجله زنان، مامایی و نازایی ایران
دوره 28، شماره 3
خرداد 1404
صفحه 26-38

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