ارزیابی اثربخشی توصیه‌های جنسی و رفتاری در بیماران مبتلا به پاپیلوماویروس انسانی پرخطر روی نتایج co test و پاپ اسمیر

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشیار گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 دستیار گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

10.22038/ijogi.2025.80082.6095

چکیده

مقدمه: با توجه به اهمیت و شیوع نسبتاً بالای پاپیلوما ویروس و احتمال ابتلاء به سرطان­ دهانه­ رحم و تأثیر عوامل فردی و اجتماعی بر آن، مطالعه حاضر با هدف ارزیابی اثربخشی توصیه ­های جنسی و رفتاری در بیماران مبتلا به پاپیلوما ویروس انسانی پرخطر (HR-HPV) انجام شد.
روش‌کار: در این مطالعه­ تحلیلی- مقطعی، 146 زن مبتلا به HR-HPV از نوع CIN I مراجعه ­کننده به بیمارستان امام حسین (ع) تهران طی سال‌های 1402-1401 دارای معیارهای ورود، به روش در دسترس انتخاب شدند. 2 جلسه­ 15 دقیقه ­ای (به فاصله یک هفته) در مورد توصیه­ های جنسی و رفتاری به‌صورت حضوری برگزار گردید. قبل و یک­ سال بعد از مداخلات آموزشی، نتایج co test و پاپ اسمیر مقایسه شد. تجزیه و تحلیل داده ­ها با استفاده از نرم ­افزار آماری SPSS (نسخه­ 23) و آزمون­ های کای دو و دقیق فیشر انجام شد. میزان p کم­تر از 05/0 معنی ­دار در نظر گرفته شد.
یافته­ ها: اثربخشی مثبت مداخلات در 112 نفر (7/76%) مشاهده شد. شیوع موارد منفی HPV پس از مداخلات آموزشی در افراد ترک­کننده­ فقط قلیان، افراد اصلاح­ کننده­ وضعیت مولتی­ پارتنری و افراد رعایت ­کننده هر دو، بر اساس نتایج co test، به‌ترتیب برابر 3/86، 9/68 و 0/70 درصد (010/0=p) و بر اساس نتایج پاپ اسمیر، به‌ترتیب برابر 1/93، 4/72 و 0/60 درصد (043/0=p) بود.
نتیجه­ گیری: انجام توصیه­ های جنسی و رفتاری، خصوصاً ترک قلیان و اصلاح وضعیت مولتی­ پارتنری، باعث کاهش شدت بیماری مبتلایان به HR-HPV می­ شود.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Effectiveness of Sexual and Behavioral Recommendation in Patients with High Risk Human Papillomavirus on Co-testing and Pap Smear Results

نویسندگان [English]

  • Farah Farzaneh 1
  • Hilda Hamesian Kashan 2
1 Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Resident, Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Considering the importance and relatively high prevalence of papillomavirus and the possibility of contracting cervical cancer and the influence of individual and social factors on it, this study was conducted with aim to evaluate the effectiveness of sexual and behavioral recommendations in patients with high-risk human papillomavirus (HR-HPV).
Methods: In this cross-sectional study, 146 women with HR-HPV of CIN I type referred to Imam Hossein (AS) Hospital in Tehran during 2022-2023 who met the inclusion criteria were selected by available method. Two 15-minute sessions (with one-week interval) of in-person sexual and behavioral advices were held. Before and one year after educational interventions, co-test and Pap smear results were compared. The data analysis was conducted using the SPSS statistical software (version 23) and Chi-square and Fisher’s exact tests. P<0.05 was considered statistically significant.
Results: The positive effectiveness of the interventions was observed in 112 people (76.7%). The prevalence of HPV-negative cases after educational interventions based on Co-testing results in those who quit hookah only, those who modified their multi-partner status, and those who adhered to both interventions were 86.3%, 68.9%, and 70.0 %, respectively (p=0.010). According to Pap smear results, the prevalence rates were 93.1%, 72.4%, and 60.0% in the respective groups (p=0.043).
Conclusion: Carrying out sexual and behavioral recommendations, especially quitting hookah and correcting the multi-partner situation, is effective on the severity of the disease of HR-HPV sufferers.

کلیدواژه‌ها [English]

  • Papillomavirus
  • Education
  • High-risk human papillomavirus
  • Hookah
  • Multi-partner

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مجله زنان، مامایی و نازایی ایران
دوره 28، شماره 1
فروردین 1404
صفحه 1-11

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