مجله زنان، مامایی و نازایی ایران

مجله زنان، مامایی و نازایی ایران

بررسی اثرات دارچین بر تعداد، غلظت، مورفورلوژی و حرکت اسپرم: مرور نظام‌مند

نوع مقاله : مروری

نویسندگان
عارف عادلی مسبب 1
دکتر غزاله اسلامیان 2
نگین مجدی 3
1 دانشجوی کارشناسی ارشد علوم و صنایع غذایی، کمیته تحقیقات دانشجویی، دانشکده علوم تغذیه و صنایع غذایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.
2 استادیار گروه تغذیه سلولی مولکولی، دانشکده علوم تغذیه و صنایع غذایی، انستیتو تحقیقات تغذیه‌ای و صنایع غذایی کشور، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.
3 دانشجوی کارشناسی ارشد علوم و صنایع غذایی، دانشکده علوم و فناوری های پزشکی، واحد علوم و تحقیقات دانشگاه ازاد اسلامی، تهران، ایران.
10.22038/ijogi.2025.84349.6280
چکیده
مقدمه: از جمله علل ناباروری مردان، اختلالات اسپرم شامل تغییر در غلظت، زنده‌مانی، حرکت و مورفولوژی اسپرم ­ها می ­باشد. در گذشته استفاده از ترکیبات گیاهی نظیر پوست درخت دارچین به‌عنوان درمانی سنتی برای کمک به درمان مشکلات باروری محسوب می­شد. مطالعه حاضر با هدف تعیین اثر دارچین و مشتقات آن بر پارامترهای کیفی اسپرم و اثرات آن انجام شد.
روش‌کار: در این مرور نظام­ مند، کلیدواژه­ های مرتبط با ناباروری مردان، دارچین، عملکرد تولیدمثلی، اسپرماتوژنز، تعداد اسپرم، اسپرم زنده، مورفورلوژی اسپرم و حرکت اسپرم در پایگاه­ های اطلاعاتی شاملMedline ، Embase، Google Scholar، Web of Science ، Science Direct،Scopus ،Magiran ،SID ، ISC و Cochrane از ژوئن 2012 تا اکتبر 2023 به زبان­های فارسی و انگلیسی جستجو شد.
یافته ­ها: در این مرور نظام­ مند، 13 مطالعه بررسی شد. دارچین سبب بهبود پارامترهای اسپرم می­شود. مصرف دارچین باعث افزایش غلظت، زنده‌مانی، کاهش اسپرم با مورفولوژی غیرطبیعی، افزایش کیفیت اسپرم و بهبود یکپارچگی DNA اسپرم ­ها در انسان­ ها و حیوانات می­شود. استفاده از 75 میلی­ گرم بر کیلوگرم وزن بدن دارچین سبب بهبود تحرک اسپرم در موش ­های صحرایی شد. همچنین استفاده از این ماده به‌ویژه در موش­ های صحرایی مبتلا به دیابت، سبب افزایش تعداد و تحرک اسپرم شد. استفاده توأم این ماده همراه با دیگر مواد گیاهی، سبب افزایش معنی­ دار در درصد زنده‌مانی و تعداد اسپرم­ها شد.
نتیجه ­گیری: دارچین و مشتقات آن سبب افزایش غلظت، زنده‌مانی، حرکت و بهبود مورفولوژی اسپرم ­ها در مطالعات انسانی و حیوانی شده است که به‌طور بالقوه در افزایش نرخ باروری می ­تواند نقش داشته باشد. مصرف دوزهای متناسب و طولانی مدت دارچین و مشتقات آن می تواند به‌طور معنی ­داری، ویژگی­ های اسپرم را بهبود ببخشد. 
کلیدواژه‌ها
تحرک اسپرم
دارچین
زنده‌مانی اسپرم
غلظت اسپرم
مورفولوژی اسپرم
موضوعات

عنوان مقاله English

The effects of cinnamon consumption on sperm count, concentration, morphology, and motility: A systematic review

نویسندگان English

Aref Adeli Mosabbeb 1
Ghazaleh Eslamian 2
Negin Majdi 3
1 M.Sc. Student of Food Sciences and Technology, Student Research Committee, School of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Assistant Professor, Department of Cellular and Molecular Nutrition, School of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 M.Sc. Student of Food Sciences and Technology, School of Medical Sciences and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
چکیده English

Introduction: Some of the causes of male infertility are sperm disorders including changes in sperm concentration, viability, motility, and morphology. Historically, traditional remedies like cinnamon bark have been utilized for treating fertility issues. The present study was conducted with aim to assess the impact of cinnamon and its derivatives on sperm quality parameters.
Methods: In this systematic review, keywords related to male infertility, cinnamon, reproductive function, spermatogenesis, sperm count, vital sperm, sperm morphology, and sperm motility were searched in English and Persian databases including Medline, Embase, Google Scholar, Web of Science, Science Direct, Scopus, Magiran, SID, ISC, and Cochrane from June 2012 to October 2023.
Results: This systematic review examined 13 studies. The use of cinnamon improves sperm parameters. Cinnamon consumption increases concentration, viability, reduces sperm with abnormal morphology, increases sperm quality, and improves sperm DNA integrity in both humans and animals. The use of 75 mg/kg body weight of cinnamon improved sperm motility in male rats. Additionally, the use of cinnamon, especially in rats with diabetes, increases sperm count and motility. The combined use of cinnamon with other herbal ingredients resulted in a significant increase in the percentage of sperm viability and count.
Conclusion: Cinnamon and its derivatives have been shown to increase sperm concentration, viability, motility, and morphology in both human and animal studies, potentially leading to increased fertility rates. Therefore, long-term and adequate doses of cinnamon and its derivatives can significantly improve sperm characteristics.

کلیدواژه‌ها English

Cinnamon
Sperm concentration
Sperm morphology
Sperm motility
Sperm viability
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مجله زنان، مامایی و نازایی ایران
دوره 27، شماره 12
اسفند 1403
صفحه 79-94