بررسی تأثیر داروهای گیاهی بر درمان تهوع و استفراغ بارداری: یک مطالعه مروری نظام‌مند

نوع مقاله : مروری

نویسندگان

1 استادیار، مرکز تحقیقات مامایی و بهداشت باروری، گروه مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 کارشناس ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

10.22038/ijogi.2024.79603.6075

چکیده

مقدمه: تهوع و استفراغ در میان زنان باردار از شیوع بسیار بالایی برخوردار است. مطالعه سیستماتیک حاضر با هدف بررسی تأثیر داروهای گیاهی بر درمان تهوع و استفراغ مادران باردار صورت گرفت.
روشکار: در این مطالعه مروری نظام‌مند جهت یافتن مطالعات، کارآزمایی‌های بالینی دوسوکور و سه‌سوکور با گروه کنترل پلاسبو که به سایر درمان­ ها نظیر طب سوزنی نپرداخته‌اند، پایگاه‌های اطلاعاتی بین‌المللی google scholar، pubmed، web of science، Scopus، science direct، Cochran library و پایگاه‌های داخلی Iranmedex،Irandoc ،Magiran و SID با استفاده از کلمات کلیدی شامل: Morning sickness، nausea، vomiting، pregnancy، herbal treatment، herbal medicine و herbal remedy با عملگرهای بولین AND و OR مورد بررسی قرار گرفتند. در نهایت دو پژوهشگر به‌طور مستقل مقالات را جهت ارزیابی کیفیت به‌وسیله چک‌لیست ورهاگن و استخراج داده ­های اصلی آنها مورد بررسی قرار دادند.
یافته­ ها: در این مطالعه، 19 مقاله با حجم نمونه کلی 1593 نفر مورد ارزیابی قرار گرفت. سال انتشار مقالات تا آپریل 2023 بود و در تمامی آنها از گروه کنترل پلاسبو استفاده شده بود. به‌جز یک مطالعه که به‌صورت متقاطع انجام گرفته بود، طراحی سایر مطالعات به‌صورت موازی بود و به‌جز 2 مقاله، سایر مقالات نمره­ 3 یا بیشتر را از چک‌لیست ارزیابی کیفیت ورهاگن دریافت کردند. به‌طور کلی نتایج نشان داد که زنجبیل، لیمو، نعناع، هل و نیز ترکیب نعناع و لیمو در اکثر موارد می­ تواند در کاهش شدت و دفعات تهوع و استفراغ مؤثر واقع شود.
نتیجه ­گیری: بر اساس مطالعات انجام گرفته، گیاهان دارویی می‌توانند تأثیرات مثبتی بر کاهش تهوع و استفراغ صبحگاهی مادران باردار داشته باشند و با کمترین عوارض، استفاده شوند.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

The Effect of Herbal Medicines on Treatment of Nausea and Vomiting in Pregnancy: A Systematic Review

نویسندگان [English]

  • Elham Zare 1
  • Seideh Hanieh Alamolhoda 1
  • Asma Zalpoor 2
  • Atena Hakimzadeh 2
  • Razieh Mohammadi Chermahini 2
  • Fatemeh Vakili 2
1 Assistant Professor, Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 M.Sc. of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Nausea and vomiting are very common among pregnant women. The current systematic study was conducted with aim to investigate the effect of herbal medicines on the treatment of nausea and vomiting in pregnant mothers.
Methods: In this systematic review, to find double- and triple-blind clinical trial studies with a placebo control group that did not study other treatments such as acupuncture, the international databases of PubMed, Web of Science, Scopus, Science Direct, Cochran Library, Google Scholar, and internal databases of SID, Magiran, Irandoc, and Iranmedex were investigated using the keywords including: Morning sickness, nausea, vomiting, pregnancy, herbal treatment, herba medicine, herbal remedy with Boolean operators AND and OR. Finally, two researchers independently examined the articles to evaluate the quality using Verhagen's checklist and extract their main data.
Results: In this study, 19 articles with a total sample size of 1593 were evaluated. The year of publication of the articles was from 2001 to April 2023, and a placebo control group was used in all of them. Except for one study that was conducted as cross-sectional, the design of the other studies was parallel and except for 2 articles, the other articles received a score of 3 or more from Verhagen's quality assessment checklist. In general, the results showed that ginger, lemon, mint, cardamom and the combination of mint and lemon can be effective in reducing the intensity and frequency of nausea and vomiting in most cases.
Conclusion: According to the studies, medicinal plants can have a positive effect on reducing morning nausea and vomiting in pregnant mothers and can be used with minimal side effects.

کلیدواژه‌ها [English]

  • Herbal medicine
  • Morning sickness
  • Nausea
  • Vomiting
  • Pregnancy
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