گیاهان دارویی مؤثر بر خونریزی های زنان و مامایی: مرور سیستماتیک بر کارآزمایی های بالینی انجام شده

نوع مقاله : مروری

نویسندگان

1 کارشناس ارشد مامایی، گروه مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی تربت‌حیدریه، تربت‌حیدریه، ایران.

2 دکتری بهداشت باروری، گروه مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی تربت‌حیدریه، تربت‌حیدریه، ایران.

3 کارشناس ارشد مامایی، مرکز تحقیقات علوم بهداشتی، دانشگاه علوم پزشکی تربت‌حیدریه، تربت‌حیدریه، ایران.

چکیده

مقدمه: هر زنی در طول زندگی خود ممکن است با خونریزی‌های تهدید‌کننده حیات مانند خونریزی‌های طی بارداری، زایمان و پس از آن و یا خونریزی‌هایی که کمتر تهدید‌کننده حیات بوده، اما زندگی زن را تحت‌الشعاع قرار می‌دهد مانند خونریزی‌های غیر‌طبیعی رحمی مواجه گردد. با توجه به اهمیت پیشگیری و مهار خونریزی‌های مامایی و لزوم یافتن روش درمانی مؤثر و کم‌عارضه، مطالعه حاضر با هدف ارزیابی و جمع‌بندی نتایج کارآزمایی‌های بالینی انجام‌ شده در مورد تأثیر گیاهان دارویی مؤثر بر خونریزی‌های مامایی انجام شد.
روشکار: در این مطالعه مروری تمامی مطالعات مرتبط (بر اساس PRISMA) از پایگاه‌های اطلاعاتی مرکز ثبت کارآزمایی‌های بالینی Google scholar، Scopus، IranMedex، SID، Medlib، Magiran و PubMed با کلیدواژه‌های بارهنگ کبیر، بارهنگ نیزه‌ای، گلنار، زنجبیل، بابونه، بومادران، هسته انگور، زیره، شوید، رازیانه، ویتاگنوس، خونریزی پس از زایمان، خونریزی قاعدگی، خونریزی، منوراژی، کارآزمایی بالینی، طب سنتی و معادل انگلیسی آنها بدون محدودیت زمانی تا نوامبر 2021 جستجو شدند. تجزیه و تحلیل مطالب به‌صورت کیفی صورت گرفت.
یافته‌ها: در این مطالعه، 148 مقاله استخراج شد. سپس 28 کارآزمایی بالینی که بر اساس جداد نمره 3 یا بیشتر گرفتند و معیار‌های مطالعه را داشتند، وارد مطالعه شدند. مقالات مربوط به 10 نوع از گیاهان دارویی با حجم نمونه 2666 نفر مورد بررسی قرار گرفتند که نتایج این مطالعات نشان می‌دهد گیاهان مورد بررسی در کاهش خونریزی‌های زنان و مامایی مؤثر بوده‌اند.
نتیجه‌گیری: از گیاهان دارویی مورد بررسی در این مطالعه می‌توان برای پیشگیری و کنترل خونریزی در زنان استفاده کرد. با این حال، قضاوت در مورد تأثیر قطعی این مداخلات قطعاً مستلزم مطالعات گسترده‌تری است. 

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of Medicinal Plants on Gynecological and Obstetric Hemorrhages: A Systematic Review of Clinical Trials

نویسندگان [English]

  • Seyedeh Adeleh Rahmanian 1
  • Morvarid Irani 2
  • Maryam Aradmehr 3
1 M.Sc. in Midwifery, Department of Midwifery, School of Nursing and Midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
2 PhD in Reproductive Health, Department of Midwifery, School of Nursing and Midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
3 M.Sc. in Midwifery, Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
چکیده [English]

Introduction: Every woman during her life may experience life-threatening bleeding such as bleeding during pregnancy, childbirth and after delivery, or bleeding which is less life-threatening but overshadows the woman's life, such as abnormal uterine bleeding (AUB). Regarding to the importance of preventing and controlling the obstetrics bleeding and the need to find an effective and low-complication treatment method, this systematic review was conducted with aim to determine the effect of herbal medicines on gynecological and obstetric hemorrhages.
Methods: In this systematic review study, all the related studies (based on PRISMA) were searched in databases of clinical randomized registration center and PubMed, Magiran, Medlib, SID, IranMedex, Scopus, and Google scholar using the key words of ( Plantago major, plantain, Plantago (lanceolate), Punica granatum, Persian gulnar, Ginger, Zingiber officinale, Chamomile, Achillea millefolium, Grape Seed, cumin (cuminum), Anethum graveolens (dill), Foeniculum (Fennel), Vitex (Chasteberry), postpartum hemorrhage, Menstrual bleeding, bleeding, menorrhagia, randomized clinical trial, and traditional medicine without time limitation until Nov 2021. Data were analyzed qualitatively.
Results In this study, 148 articles were extracted. Also, 28 clinical trials which received Jedad score ≥ 3 and met the inclusion criteria entered the study. The articles related to 10 types of medicinal plants with a sample size of 2666 people were studied. According to the results, the studied plants were effective in reducing gynecological and obstetric hemorrhages.
Conclusion: The medicinal plants studied in this study can be used for preventing and controlling bleeding in women. However, judging the definite effect of these interventions definitely requires more extensive studies.
 

کلیدواژه‌ها [English]

  • Bleeding
  • Clinical trial
  • Medicinal Plants
  • Menorrhagia
  • Menstruation
  • Postpartum Hemorrhage
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