بررسی اثر مصرف قهوه در مقایسه با رژیم تغذیه‌ای معمول بر بهبود عملکرد روده پس از هیسترکتومی ابدومینال: یک مطالعه کارآزمایی بالینی تصادفی شده دوسویه‌کور

نوع مقاله : اصیل پژوهشی

نویسندگان

1 استاد گروه زنان و مامایی، مرکز تحقیقات نوزادان، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 استادیار گروه پزشکی اجتماعی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

3 رزیدنت گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

4 دکتری پزشکی عمومی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: ایلئوس پس از عمل منجر به ناراحتی بیمار، طولانی­شدن مدت بستری و تحمیل هزینه به سیستم­ بهداشتی می­شود. در تعداد کمی از مطالعات از نقش احتمالی مصرف قهوه در کاهش بروز ایلئوس حمایت شده­ است. مطالعه حاضر با هدف بررسی تأثیر مصرف قهوه در ­مقایسه با رژیم تغذیه­ای معمول بر بهبود عملکرد روده پس از هیسترکتومی ابدومینال انجام­ گرفت.
روش‌کار: این مطالعه کارآزمایی ­بالینی ­تصادفی دو­سو­کور در سال 1400-1399 بر ­روی 40 بیمار کاندید هیسترکتومی به‌دلیل بیماری خوش­خیم­ رحمی که به بیمارستان امام رضا (ع) مشهد مراجعه کرده ­بودند، انجام شد. افراد به دو­ گروه تقسیم شدند که از روز بعد از عمل به فاصله زمانی هر 6 ساعت تا 3 ­نوبت، در گروه مداخله میزان 100 میلی­لیتر قهوه و در گروه کنترل میزان 100 میلی­لیتر رنگ ­مجاز خوراکی و اسانس شبیه قهوه مصرف شد. پیامد اولیه، بررسی زمان اولین دفع ­گاز و پیامد‌های ثانویه، بررسی زمان اولین صدای­ روده­ای، اولین اجابت­ مزاج و میزان بروز ایلئوس بعد از عمل بود. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 27) انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته­ها: در مقایسه زمان اولین صدای ­روده­ای (02/0=p)، اولین دفع­ گاز (007/0=p) و اولین اجابت­ مزاج (001/0>p) بین دو گروه مداخله و کنترل تفاوت آماری معناداری وجود ­داشت. هیچ موردی از ایلئوس­ شدید مشاهده ­نشد. در مقایسه بین عدم بروز ایلئوس با مجموع موارد ایلئوس خفیف و متوسط تفاوت بین دو­ گروه معنادار بود (047/0=p). مقایسه مدت زمان بستری بین دو ­گروه معنادار نبود (24/0=p).
نتیجه­گیری: در مقایسه زمان اولین صدای روده­ای، اولین دفع گاز، اولین اجابت مزاج و بروز ایلئوس بین دو گروه مداخله و کنترل تفاوت آماری معناداری وجود داشت. چنین به­نظر می­رسد که مصرف قهوه پس از عمل هیسترکتومی ­ابدومینال موجب تسریع شروع حرکات­ روده­ای و کاهش بروز ایلئوس می­شود.

کلیدواژه‌ها

عنوان مقاله [English]

The effect of coffee consumption on improving bowel function after abdominal hysterectomy compared to routine diet: a randomized double-blind clinical-trial

نویسندگان [English]

  • Nayereh Ghomian 1
  • Majid Khadem Rezaiyan 2
  • Zahra Behnam Rassouli 3
  • Mostafa Zemorshidi 4
1 Professor, Department of Obstetrics and Gynecology, Neonatal Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Assistant professor, Department of Social Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Resident, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4 General Practitioner, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction: Postoperative ileus causes patient discomfort, prolonged hospitalization and extra costs on health system. Few studies support the possible role of coffee consumption in reducing the incidence of ileus. The present study was performed aimed to investigate the role of coffee consumption in comparison with routine diet on improving intestinal function after abdominal hysterectomy.
Methods: This randomized double-blind clinical trial study was performed in 2020-2021 on 40 patients candidate for hysterectomy due to benign uterine disease who had referred to Imam Reza hospital in Mashhad. The patients were divided into two groups and from the day after surgery, every 6 hours for three times, patients in intervention group consumed 100 ml of coffee and patients in control group consumed 100 ml of food coloring and essence similar to coffee. The primary outcome was the time of first gas passing and secondary outcomes were the time of first bowel sound, first defecation and incidence of postoperative ileus. Data were analyzed by SPSS 27 software (version 27). P< 0.05 was considered statistically significant.
Results: There was a statistically significant difference between the two groups in comparing the time of first bowel sound (P=0.02), first gas passing (P=0.007) and first defecation (P<0.00). There was no case of severe ileus in participants. In comparison between the absence of ileus with the sum of mild and moderate ileus cases, the difference between two groups was significant (P=0.047). Comparison of hospitalization period was not significant between the two groups (P=0.24).
Conclusion: There was a statistically significant difference between the intervention and control groups in comparing the time of first bowel sound, first gas passing, first defecation and incidence of ileus. It seems that coffee consumption after abdominal hysterectomy accelerates the onset of intestinal movements and reduces the incidence of ileus.

کلیدواژه‌ها [English]

  • Coffee
  • Hysterectomy
  • Ileus

مراجع

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مجله زنان، مامایی و نازایی ایران
دوره 25، شماره 5
مرداد 1401
صفحه 1-10

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