مجله زنان، مامایی و نازایی ایران

مجله زنان، مامایی و نازایی ایران

بررسی سرواپیدمیولوژیک آنتی‌بادی IgG ضدکلامیدیا تراکوماتیس در زنان بی‌علامت مشهد

نوع مقاله : اصیل پژوهشی

نویسندگان
دکتر مسعود یوسفی 1
دکتر حسین پریزاد 2
دکتر هادی فارسیانی 3
دکتر مجید خادم رضاییان 4
1 دانشیار گروه میکروب شناسی و ویروس شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.
2 پزشک عمومی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.
3 استادیار گروه میکروب شناسی و ویروس شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.
4 استادیار گروه پزشکی اجتماعی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.
10.22038/ijogi.2022.20047
چکیده
مقدمه: کلامیدیا تراکوماتیس، عامل عفونت کلامیدیایی دستگاه تناسلی و تراخم، شایع‌ترین عفونت باکتریایی منتقله از راه تماس جنسی و مهم‌ترین و پرهزینه‌ترین بیماری منتقله مقاربتی غیرویروسی می­باشد. این عفونت یک عامل شایع برای ایجاد یورتریت در مردان و سرویسیت در زنان است و عوارض زیادی مانند ناباروری و حاملگی خارج رحمی برای آن ذکر شده است. مطالعه حاضر با هدف بررسی فراوانی آنتی‌بادی ضدکلامیدیا در زنان بدون علامت سنین باروری مراجعه‌کننده به مراکز بهداشتی- درمانی شهر مشهد انجام شد.
روش‌کار: این مطالعه مقطعی در سال 1395 بر روی 93 نفر از زنان مراجعه‌کننده به مراکز بهداشت تحت پوشش دانشگاه علوم پزشکی مشهد انجام شد. آنتی‌بادی IgG ضدکلامیدیا در این نمونه­ها با روش ELISA بررسی شد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 16) و آزمون دقیق فیشر فریمن هالتون انجام شد. میزان p کمتر از 05/0 معنادار در نظر گرفته شد.
یافته­ها: در مجموع 93 زن مورد ارزیابی قرار گرفتند که میانگین سطح سرمی آنتی‌بادی در آنها 36/0±35/0 نانوگرم در دسی‌لیتر بود و بر این اساس، 6 نفر (5/6%) نتیجه مثبت داشتند. همچنین در این مطالعه رابطه عفونت با سن (209/0=p) و منطقه زندگی (239/0=p) این افراد بررسی شد که ارتباط معنی‌داری یافت نشد.
نتیجه­گیری: بر اساس مطالعه حاضر، فراوانی آنتی‌بادی ضدکلامیدیا در زنان سنین باروری مراجعه‌کننده به مراکز بهداشتی- درمانی مشهد قابل توجه بود. با توجه به این شیوع و عوارض زیاد این عفونت در صورت عدم درمان، پیشنهاد می­شود برنامه غربالگری کلامیدیا تراکوماتیس به‌صورت روتین حتی برای افراد بدون علامت انجام شود.
کلیدواژه‌ها
باروری
زنان
شیوع
کلامیدیا تراکوماتیس

عنوان مقاله English

The serosurvey study of IgG antibodies to chlamydia trachomatis among asymptomatic women, Mashhad, Iran

نویسندگان English

Masoud Yousefi 1
Hosein Parizad 2
Hadi Farsiani 3
Majid Khadem Rezaiyan 4
1 Associate Professor, Department of Microbiology & Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2 General practitioner, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Assistant Professor, Department of Microbiology & Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Assistant Professor, Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده English

Introduction: Chlamydia trachomatis is the cause of chlamydial infection of the genital tract and trachoma and is the most common bacterial infection transmitted through sexual contact and the most important and costly non-viral sexually transmitted disease. This infection is a common cause of urethritis in men and cervicitis in women, and many complications such as infertility and ectopic pregnancy have been reported. This study was performed aimed to evaluate the frequency of anti-chlamydia antibodies in asymptomatic women of childbearing age referred to health centers in Mashhad.
Methods: This cross-sectional study was performed in 2016 on 93 women referring to the health care centers of Mashhad University of Medical Sciences. Anti-chlamydia IgG antibodies were tested in these samples by ELISA method. Data were analyzed using SPSS software (version 16) and Fisher Freeman Halton Exact test. P<0.05 was considered statistically significant.
Results: A total of 93 women were evaluated. The mean serum level of antibody was 0.35±0.36 ng/dl and accordingly 6.5% (n=6) had a positive result. Also, the relationship between infection and age (p=0.209) and living area (p=0.239) of ​​these people was examined, but no significant relationship was found.
Conclusion: According to the results of the present study, the frequency of anti-chlamydia antibodies was considerable in women of reproductive age referred to the health centers in Mashhad. Due to this prevalence and high complications of this infection in case of no treatment, it is recommended that the Chlamydia Trachomatis screening program be performed routinely even for asymptomatic individuals.

کلیدواژه‌ها English

Fertility
Chlamydia trachomatis
Prevalence
Women
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مجله زنان، مامایی و نازایی ایران
دوره 24، شماره 13
اسفند 1400
صفحه 90-99