اثرات گیاه رزماری بر خونریزی و درد ناشی از لوله‌گذاری پس از بیهوشی عمومی زنان کاندید جراحی پستان: یک کارآزمایی بالینی تصادفی شده

نوع مقاله : اصیل پژوهشی

نویسندگان

1 استادیار گروه بیهوشی، دانشکده پزشکی، دانشگاه علوم پزشکی تبریز، تبریز، ایران.

2 استادیار گروه هوشبری و اتاق عمل، دانشکده پیراپزشکی، دانشگاه علوم پزشکی تبریز، تبریز، ایران

چکیده

مقدمه: خونریزی به‌دنبال انتوباسیون و اکستوباسیون پس از بیهوشی عمومی، عارضه‌ای نسبتاً شایع است که در برخی اعمال جراحی همچون جراحی­های پستان با شیوع بالایی همراه است. استفاده از داروهای سنتی به‌دلیل عوارض ناچیزی که به‌دنبال دارند، با استقبال متخصصین بیهوشی همراه شده است. مطالعه حاضر با هدف بررسی اثرات گیاه رزماری بر خونریزی و درد ناشی از لوله­گذاری پس از بیهوشی عمومی زنان کاندید جراحی پستان انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی در طی سال‌های 97-1396 بر روی 70 بیمار نیازمند بیهوشی عمومی در بیمارستان امام رضا (تبریز) انجام شد. افراد به‌روش تصادفی در دو گروه مداخله (گذاشتن گاز استریل آغشته به رزماری در حلق بیمار) و کنترل (گذاشتن گاز استریل آغشته به آب مقطر در حلق بیمار) تقسیم شدند. مشاهده خونریزی و درد ناشی از انتوباسیون به کمک مقیاس دیداری درد در ریکاوری و ساعات 2، 6 و 24 پس از جراحی اندازه‌گیری شد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 25) و آزمون‌های کای دو و تی مستقل انجام شد. میزان p کمتر از 05/0 معنادار در نظر گرفته شد.
یافته‌ها: در این مطالعه 11 نفر (42/31%) از بیماران گروه مداخله و 14 نفر (40%) از بیماران گروه کنترل دارای خونریزی پس از اکستوباسیون بودند (309/0=p). همچنین تعداد درد ناشی از انتوباسیون (05/0<p) و شدت درد (05/0<p) در زمان­های مختلف بین دو گروه اختلاف آماری معناداری نداشت.
نتیجه‌گیری: پک­های استریل آغشته شده به عصاره رزماری نتوانست از خونریزی و درد ناشی از انتوباسیون در زنان کاندید جراحی­ های پستان پیشگیری نماید.

کلیدواژه‌ها


عنوان مقاله [English]

Effects of Rosemary on Bleeding and Pain following Intubation after General Anesthesia in Women Candidates for Breast Surgery: A Randomized Clinical Trial Study

نویسندگان [English]

  • Abbasali Dehghani 1
  • Reyhaneh Abri Sardaroudi 2
1 Assistant Professor, Department of Anesthesiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Assistant Professor, Department of Anesthesiology and Operating Room, School of Paramedical, Tabriz University of Medical Sciences, Tabriz, Iran.
چکیده [English]

Introduction: Bleeding following intubation and extubation after general anesthesia is a relatively common complication that is associated with a high prevalence in some surgeries such as breast surgeries. The use of traditional medicines has been welcomed by anesthesiologists due to their minor side effects. This study was performed with aim to investigate the effects of rosemary on bleeding and pain of intubation after general anesthesia for women candidates for breast surgery.
Methods: The clinical trial study was performed in 2017-2018 on 70 patients who need general anesthesia in Imam Reza Hospital, Tabriz. The subjects were randomly divided into two groups of intervention (inserting sterile gas impregnated with rosemary in the patient's throat) and control (inserting sterile gas impregnated with stilled water in the patient's throat). Observation of bleeding and pain due to intubation was measured by VAS instrument in the recovery and 2, 6, 24 hours after the surgery. Data were analyzed by SPSS statistical software (version 25) and independent t-test and chi-square test. P<0.05 was considered sttisticallyy significant.
Results: Eleven patients (31.42%) in the intervention group and 14 (40%) in the control group had post-extubation bleeding (P = 0.309). Also, the number of pain due to intubation (P <0.05) and pain intensity (P >0.05) at different times showed no statistically significant difference between the two groups.
Conclusion: Sterile packs impregnated with rosemary extract could not prevent bleeding and pain due to intubation in women candidates for breast surgery.

کلیدواژه‌ها [English]

  • Bleeding
  • Intubation
  • Pain
  • rosemary extract
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