بررسی تأثیر آلوئه‌ورا بر کاهش درد و بهبود زخم اپی‌‌زیاتومی: یک مطالعه مرور سیستماتیک و متاآنالیز

نوع مقاله : مروری

نویسندگان

1 دانشجوی دکتری تخصصی بهداشت باروری، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 دانشیار گروه مامایی، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 دانشجوی دکتری تخصصی بهداشت باروری، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران. دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی زنجان، زنجان، ایران.

4 استادیار گروه مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی البرز، کرج، ایران.

چکیده

مقدمه: اپی‌زیاتومی یکی از دلایل درد مادران و کاهش کیفیت زندگی پس از زایمان است. گیاه آلوئه‌ورا به‌عنوان یکی از راهکارهای ترمیم زخم و کاهش درد مطرح‌ شده است. با توجه به این خواص تاکنون چندین مطالعه کارآزمایی بالینی جهت تعیین تأثیر آلوئه‌ورا بر کاهش درد و بهبود زخم اپی‌زیاتومی انجام‌ شده و یافته‌های متفاوتی نیز گزارش ‌شده است؛ مطالعه حاضر با هدف تعیین تأثیر آلوئه‌ورا بر کاهش درد و بهبود زخم اپی‌زیاتومی انجام شد.
روش‌کار: در این مطالعه مرور سیستماتیک پایگاه‌های اطلاعاتی شامل: Cochrane Library، Proques، Web of Science،Scopus ، (MEDLINE) PubMed، Embase وCochrane Central Register of Controlled Trials (CENTRAL) با استفاده از عملگرهای بولین شامل AND و OR و کلیدواژه‌های مش شامل درد، زخم، بهبود، اپی‌زیاتومی، پرینه و آلوئه‌ورا بدون محدودیت زمانی، مکانی و زبانی تا تاریخ 23 آپریل سال 2021 مورد بررسی قرار گرفت. ارزیابی کیفیت مقالات با استفاده از ابزار گروه کوکران و تجزیه ‌و تحلیل داده‌ها با استفاده از نرم‌افزار Stata (نسخه 14) انجام شد. جهت بررسی همگنی بین مطالعات از شاخص I2 و آزمون کوکران استفاده شد.
یافته‌ها: در نهایت 9 مقاله با حجم نمونه 611 نفر وارد مطالعه مروری سیستماتیک شد. نتایج مطالعات اولیه حاکی از تأثیر آلوئه‌ورا در بهبود زخم و کاهش درد بود. 4 مطالعه با حجم کلی 258 نفر قابلیت انجام متاآنالیز برای پیامد درد را داشت. نتایج متاآنالیز نشان داد که گیاه آلوئه‌ورا در مقایسه با گروه کنترل می‌تواند باعث کاهش شدت درد شود (05/0p<).
نتیجه‌گیری: به‌نظر می‌رسد گیاه آلوئه‌ورا در ترمیم زخم اپی‌زیاتومی و کاهش درد آن مؤثر است؛ اما جهت نتیجه‌گیری قطعی، مطالعات با کیفیت بالا و حجم کافی پیشنهاد می‌شود.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of Aloe vera on reducing episiotomy pain and improving wound healing: A systematic review and meta-analysis

نویسندگان [English]

  • Hadis Shahrahmani 1
  • Giti Ozgoli 2
  • Fatemeh Bayat 3
  • Maryam Amighi 1
  • Fatemeh Abdi 4
  • Nourossadat Kariman 2
1 PhD student of Reproductive Health, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Associate professor, Department of Midwifery, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 PhD student of Reproductive Health, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. School of Nursing and Midwifery, Zanjan University of Medical Sciences, Zanjan , Iran.
4 Assistant Professor, Department of Midwifery, School of Nursing and Midwifery, Alborz University of Medical Sciences, Karaj, Iran.
چکیده [English]

Introduction: Episiotomy is one of the causes that can affect mothers' postpartum quality of life. Aloe Vera plant has been suggested as one of the ways to heal wounds and reduce pain. Regarding to these properties, several clinical trial studies have been conducted to determine the effect of aloe vera on episiotomy pain relief and wound healing, and different findings have been reported. This study was performed with aim to determine the effect of Aloe Vera on episiotomy pain relief and wound healing.
Methods: In this systematic review study, the databases of Scopus, PubMed (MEDLINE), Embase, Proquest, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Library and Web of Science were searched using the keywords of "pain", "Wound", "Healing", "Episiotomy", " Perineum" and "Aleo Vera" by OR and AND without time, language and geographical limitation until 23 April 2021. The quality of the articles was evaluated using the Cochran Group tool and data were analyzed by Stata software (version 14). Cochran test and I2 index were used to assess the heterogeneity of the articles.
Results: Finally, 9 articles with sample size of 611 people were included in this systematic review study. Preliminary studies showed the effectiveness of Aloe Vera in wound healing and pain relief. Four studies with sample size of 258 patients had the potential to perform the meta-analysis for pain outcome. Results of the meta-analysis showed that Aloe vera can reduce pain intensity compared to the control group (P<0.05).
Conclusion: Aloe Vera seems to be effective in repairing episiotomy wounds and reducing pain; however, high quality studies with sufficient sample size are recommended for definitive results.

کلیدواژه‌ها [English]

  • Aloe vera
  • Episiotomy
  • Pain
  • Perineum
  • Systematic review
  • Wound
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