بررسی ارتباط شاخص توده بدنی با پیشگویی کننده‌های بالینی سندرم تخمدان پلی‌کیستیک در نوجوانان دختر

نویسندگان

1 دانشجوی دکترای تخصصی بهداشت باروری، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 استاد گروه زنان و مامایی، مرکز تحقیقات اندوکرینولوژی تولید مثل، پژوهشکده علوم غدد درون‌ریز و متابولیسم، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 دانشیار گروه مامایی و سلامت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

4 استادیار گروه تغذیه، دپارتمان تحقیقات تغذیه، انستیتو تحقیقات تغذیه‌ای و صنایع غذایی کشور، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

5 دکترای تخصصی سلامت روان‌شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

6 استاد گروه آمار زیستی، دانشکده پیراپزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

چکیده

مقدمه: سندرم تخمدان پلی‌کیستیک یکی از شایع‌ترین بیماری‌های غدد درون‌ریز نوجوانان در جهان است که بر مسائل مربوط به باروری در سنین بزرگسالی آنها تأثیر منفی دارد. از آنجایی که با افزایش وزن نوجوان احتمال بروز علائم بیماری افزایش پیدا می­کند، مطالعه حاضر با هدف بررسی ارتباط بین شاخص توده بدنی نوجوانان و علائم بالینی پیش‌بینی کننده سندرم تخمدان پلی‌کیستیک انجام شد.
روش‌کار: این مطالعه توصیفی - تحلیلی در سال 1398 بر روی 751 نوجوان 18-16 ساله در معرض خطر سندرم تخمدان پلی‌کیستیک در دبیرستان‌های دخترانه شهر تهران انجام شد. وضعیت شاخص توده بدنی، سیکل قاعدگی، ریزش مو، آکنه و هیرسوتیسم واحدهای پژوهش مورد بررسی قرار گرفت. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 25) و آزمون‌های آماری کای دو و رگرسیون لوجستیک انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: بر اساس نتایج مطالعه، بین شاخص توده بدنی با نظم سیکل قاعدگی (142/0=p) و آکنه (64/0=p) ارتباط معنی‌داری وجود نداشت، ولی بین شاخص توده بدنی با هیرسوتیسم (02/0=p) و ریزش مو (03/0=p) ارتباط مثبت و معنی‌داری وجود داشت.
نتیجه‌گیری: افزایش شاخص توده بدنی با افزایش شدت علائم بالینی هایپرآندروژنیسم مانند ریزش مو و هیرسوتیسم در نوجوانان دختر در معرض خطر سندرم تخمدان پلی‌کیستیک همراه می­باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Relationship between body mass index and the clinical predictors of polycystic ovary syndrome in adolescent girls

نویسندگان [English]

  • Somayeh Abdolahian 1
  • Fahimeh Ramezani Tehrani 2
  • Fatemeh Nahidi 3
  • Delaram Ghodsi 4
  • Mahdi Jafari 5
  • Hamid Alavi Majd 6
1 PhD student of Reproductive Health, Department of Midwifery and Reproductive Health, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Professor, Department of Obstetrics and Gynecology, Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences and Metabolism, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Associate Professor, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Assistant Professor, Department of Nutrition, Nutrition Research Department, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5 PhD in Health Psychology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
6 Professor, Department of Biostatics, School of Paramedicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Polycystic ovary syndrome is one of the most common endocrine diseases of adolescents in the world, which has negative effects on fertility issues in adulthood. Since adolescent weight gain increases the risk of symptoms, this study was performed with aim to investigate the relationship between adolescent body mass index and clinical predicting factors of polycystic ovary syndrome.
Methods: This descriptive- analytical study was conducted in 2019 on 751 adolescents aged 16 to 18 years at risk of polycystic ovary syndrome in Tehran girls' high school. Body mass index, menstrual cycle, hair loss, acne and hirsutism were examined. Data were analyzed by SPSS software (version 25) and chi-square and logistic regression tests. P<0.05 was considered statistically significant.
Results: The results of the showed that there was no significant relationship between body mass index with menstrual cycle order (p = 0.142) and also acne (p = 0.64). But significant positive relationship was found between body mass index with hirsutism (p = 0.02) and also hair loss (p = 0.03).
Conclusion: The increase in body mass index is associated with increase in the severity of clinical symptoms of hyperandrogenism such as hair loss and hirsutism in female adolescents at risk for polycystic ovary syndrome.

کلیدواژه‌ها [English]

  • Adolescents
  • Body mass index
  • Polycystic Ovarian Syndrome
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