بررسی تأثیر کپسول دانه خرفه در پیشگیری از پس‌درد زایمان در مادران چندزا: کارآزمایی بالینی تصادفی شده

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 استادیار گروه مامایی، مرکز تحقیقات مراقبت‌های پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

3 استادیار گروه فارماکولوژی، مرکز تحقیقات فارماکولوژیک و گیاهان دارویی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

4 مربی گروه پرستاری، مرکز تحقیقات مراقبت‌های پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

5 استاد گروه زنان و مامایی، مرکز تحقیقات سلامت زنان، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: پس‌درد، یکی از مشکلات دوران پس از زایمان است که جهت رفع آن گاهی نیاز به مسکن می­باشد و تسکین آن موجب بهبود شیردهی و ارتباط بهتر مادر و نوزاد می­گردد. بررسی فارماکولوژی دانه خرفه نشان‌دهنده تأثیر این گیاه در تنظیم و تعدیل درد است. مطالعه حاضر با هدف تعیین تأثیر دانه خرفه در پیشگیری از پس‌درد انجام شد.
روش‌کار: این مطالعهکارآزمایی بالینی سه‌سوکور در سال 1397 بر روی 74 مادر چندزا در شهرستان شیروان وابسته به دانشگاه علوم پزشکی خراسان شمالی انجام شد. واحد­های پژوهش به‌صورت تصادفی در دو گروه 37 نفری دانه خرفه و پلاسبو قرار گرفتند. پس از تکمیل مرحله سوم زایمان، یک عدد از کپسول­های دانه خرفه یا پلاسبو به واحد پژوهش داده می­شد. برای بیماران هر دو گروه در صورت وجود درد، مسکن تجویز می‌شد. بعد از شروع مداخله، هر 8 ساعت (تا 4 دوز) کپسول­ها مصرف می­شد. نمره پس‌درد با استفاده از مقیاس دیداری درد، بعد از شروع مداخله و یک‌ساعت قبل و پس از مصرف دوز­های بعدی اندازه‌گیری شد. تجزیه و تحلیل داده­ها با استفاده از نرم‌افزار آماری SPSS (نسخه 25) و آزمون­های من‌ویتنی، تی مستقل، فیشر و کای اسکوئر انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: شدت پس‌درد بعد از مصرف کپسول­ها در گروه دانه خرفه نسبت به گروه پلاسبو کاهش معناداری داشت (001/0>p). تعداد مسکن مصرفی مادران چندزا در گروه دانه خرفه کاهش معنی‌داری نسبت به گروه پلاسبو داشت (001/0>p).
نتیجه‌گیری: دانه خرفه در کاهش شدت پس‌درد و پیشگیری از بروز آن مؤثر است و موجب کاهش نیاز به مسکن­های خوراکی می­شود.

کلیدواژه‌ها

عنوان مقاله [English]

Effect of Purslane seed Capsule in Prevention of Postpartum after pain in Multiparous Mothers: A Randomized Clinical Trial

نویسندگان [English]

  • Mahjoubeh Ramezani motlagh 1
  • Nahid Golmakani 2
  • Hasan Rakhshandeh 3
  • Seyed Reza Mazloum 4
  • Farideh Akhlaghi 5
1 M.Sc. Student of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Assistant Professor, Department of Midwifery, Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Assistant Professor, Department of Pharmacology, Pharmacologic and Medicinal Plants Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Instructor, Department of Nursing, Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
5 Professor, Department of Obstetrics and Gynecology, Women's Health Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction: After pain is one of the postpartum problems that sometimes requires analgesics to remove it, and its relief improves lactation and better communication between mother and baby. Pharmacological evalution of Purslane seed indicates the effect of this plant on pain adjustment and regulation. This study was performed with aim to determine the effect of purslane seed in preventionof after pain.
Methods: This triple-blind clinical trial study was conducted on 74 multiparous mothers in Shirvan city affiliated to North Khorasan University of Medical Sciences in 2018. The research units were randomly divided into two groups of purslane seed (n=37) and placebo (n=37). After completing third stage of delivery, one capsule of purslane seed or placebo was given to the research unit. The patients in both groups received analgesics if they had pain. After start of the intervention, the capsules were consumed every 8 hours (up to 4 doses). The score of after pain was measured after the intervention and one hour before and after the next doses using the visual analogue scale of pain. Data were analyzed using SPSS software (version 25) and Mann-Whitney, independent t-test, Fisher, and Chi-square tests. P<0.05 was considered statistically significant.
Results: After taking capsules, the intensity of after pain in the purslane seed group significantly decreased compared to the placebo group (p<0.001). The number of consumed analgesics in multiparous mothers of purslane seed group was significantly less than the placebo group (p<0.001).
Conclusion: Purslane seed is effective in reducing the intensity of after pain and preventing it, and it reduces the need for edible analgesics.

کلیدواژه‌ها [English]

  • After pain
  • Postpartum period
  • Purslane

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مجله زنان، مامایی و نازایی ایران
دوره 22، شماره 7
مهر 1398
صفحه 47-57

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