شیوع سندرم پاهای بی‌قرار در زنان باردار در آسیا: مطالعه مرور سیستماتیک و متاآنالیز

نوع مقاله : مروری

نویسندگان

1 استادیار گروه پرستاری، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران.

2 کارشناس ارشد گروه پرستاری، واحد گرمسار، دانشگاه آزاد اسلامی، گرمسار، ایران.

3 کارشناس ارشد آمار زیستی، مرکز تحقیقات ارتقاء سلامت، دانشگاه علوم پزشکی ایران، تهران، ایران.

4 کارشناس مامایی، بیمارستان بعثت، دانشگاه علوم پزشکی کردستان، سنندج، ایران.

5 استادیار گروه پرستاری، مرکز تحقیقات مراقبت بالینی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی کردستان، سنندج، ایران.

چکیده

مقدمه: سندرم پاهای بی‌قرار نوعی اختلال نورولوژیکی است که با بروز اختلال خواب منجر به بیماری‌های قلبی عروقی، فشارخون بارداری، افسردگی و افزایش مرگ‌و‌میر مادر و جنین می‌شود. مطالعات مختلف شیوع‌های متفاوتی را گزارش کرده‌اند. مطالعه مرور سیستماتیک و متاآنالیز حاضر با هدف برآورد شیوع سندرم پاهای بی‌قرار در زنان باردار در آسیا انجام شد.
روش‌کار: در این مطالعه مروری با جستجو در پایگاه‌های اطلاعاتی ملی و بین‌المللی SID، Magiran،Google Scholar، IranMedex، Science Direct، PubMed و Scopus تعداد 16 مقاله مشاهده‌ای دارای متن کامل مربوط به سال‌های 2003 تا ژانویه 2018 استخراج شدند. جهت انجام این مطالعه متاآنالیز، از مدل اثرات تصادفی استفاده گردید و ناهمگنی مطالعات با شاخص I2 بررسی شد. آنالیز داده‌ها با نرم‌افزار STATA (نسخه 12) انجام شد.
یافته‌ها: شیوع سندرم پاهای بی‌قرار در زنان باردار آسیایی در 16 مقاله بررسی‌شده با حجم نمونه 49342 نفر، 5/18% (فاصله اطمینان 95%: 38/23-75/13%) بود. شیوع سندرم پاهای بی‌قرار بر اساس مصاحبه 04/14% (فاصله اطمینان 95%: 05/16-02/12%) و بر اساس پرسشنامه 75/22% (فاصله اطمینان 95%: 01/32-49/13%) بود. بین شیوع سندرم پاهای بی‌قرار در بیماران با سال انتشار مقالات (939/0=p)، حجم نمونه (161/0=p) و میانگین سن نمونه‌ها (105/0=p) ارتباط معناداری مشاهده نشد.
نتیجه‌گیری: سندرم پاهای بی‌قرار در زنان باردار آسیایی از شیوع بالایی برخوردار است. به دلیل پیامدهای مادری و جنینی، بررسی علل و عوامل دقیق ابتلاء به این بیماری در این گروه پرخطر ضروری به‌نظر می‌رسد.
 

کلیدواژه‌ها

عنوان مقاله [English]

Prevalence of restless legs syndrome in pregnant women in Asia: systematic review and meta-analysis

نویسندگان [English]

  • Alireza Abdi 1
  • Mahboubeh Nazari 2
  • Seyed Hassan Niksima 3
  • Vajiheh Baghi 4
  • Reza Ghanei Gheshlagh 5
1 Assistant Professor, Department of Nursing, Student Research Committee, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
2 M.Sc. of Nursing, Garmsar Branch, Islamic Azad University, Garmsar, Iran.
3 M.Sc. of Biostatistics, Health Promotion Research Center, Iran University of Medical Sciences, Tehran, Iran.
4 B.Sc. of Midwifery, Be'sat Hospital, Kurdistan University of Medical Sciences, Sanandaj, Iran.
5 Assistant Professor, Department of Nursing, Clinical Care Research Center, School of Nursing and Midwifery, Kurdistan University of Medical Sciences, Sanandaj, Iran.
چکیده [English]

Introduction: Restless legs syndrome (RLS) is a neurological disorder accompanied by sleep disturbances leading to cardiovascular diseases, gestational hypertension, depression and increased rate of maternal and fetal mortality. Different prevalence rates have been reported for RLS. This systematic review and meta-analysis was performed with aim to evaluate the prevalence of RLS among pregnant women in Asia.
Methods:  In this review study, the national and international databases, including SID, MagIran, Google Scholar, IranMedex, Science Direct, PubMed, and Scopus were searched and 16 observational studies with full texts published from 2003 to January 2018 were extracted. The meta-analysis was conducted using the Random effect model, and the I2 index was used to assess the heterogeneity between studies. Data were analyzed using STATA software (version 12).
Results: Across the 16 reviewed articles with a total sample size of 49342, the prevalence of RLS among Asian pregnant women was around 18.5% (95% confidence interval [CI]: 13.75%-23.38%). The prevalence of RLS based on interview and questionnaire was 14.04% (95% CI: 12.02%-16.05%) and 22.75% (95% CI: 13.49%-32.01%), respectively. No significant relationship was found between prevalence of RLS and year of publication (p=0.939), sample size (p=0.161), and mean age of participants (p=0.105).
Conclusion: Restless legs syndrome (RLS) is highly prevalent among Asian pregnant women. Considering the maternal and fetal outcomes of RLS, it seems necessary to examine the precise causes of its prevalence among this high-risk population.

کلیدواژه‌ها [English]

  • Asia
  • Meta-analysis
  • pregnancy
  • Prevalence
  • Restless leg syndrome

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مجله زنان، مامایی و نازایی ایران
دوره 21، ویژه نامه
شهریور 1397
صفحه 18-10

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