بررسی تأثیر عصاره مریم گلی بر علائم روحی سندرم پیش از قاعدگی

نوع مقاله : اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی تهران، تهران، ایران.

2 استاد گروه مامایی و بهداشت باروری، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 مربی گروه مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

4 استاد گروه فارماکوگنوزی، دانشکده داروسازی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

5 استادیار گروه آمار زیستی، دانشکده پیراپزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

چکیده

مقدمه: سندرم پیش از قاعدگی یکی از شایع‌ترین اختلالات روانی در زنان است که کیفیت زندگی اجتماعی آنان را به میزان قابل توجهی تحت تأثیر قرار می­دهد. برخی مطالعات حاکی از تأثیر مریم گلی بر برخی مشکلات قاعدگی است، لذا مطالعه حاضر با هدف بررسی تأثیر عصاره­ مریم گلی بر علائم روحی سندرم پیش از قاعدگی انجام گرفت.
روش‌کار: این مطالعه کارآزمایی بالینی تصادفی سه‌سوکور در سال ۱۳۹۴ بر روی ۹۰ نفر از دانشجویان خوابگاه­های دانشگاه شهید بهشتی انجام شد. نمونه­ها پس از تشخیص با فرم استاندارد تشخیص سندرم پیش از قاعدگی به‌طور تصادفی به دو گروه تقسیم شدند و به مدت دو ماه متوالی از روز ۲۱ سیکل قاعدگی تا روز پنجم سیکل بعدی با کپسول‌های ۵۰۰ میلی‌گرمی مریم گلی یا پلاسبو ‌یک بار در روز تحت درمان قرار گرفتند. ابزار گردآوری داده‌ها پرسشنامه و فرم ثبت وضعیت روزانه علائم بود. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه ۲۰) و آزمون‌های تی‌تست، کای اسکوئر، من ویتنی و اندازه‌گیری‌های مکرر انجام شد. میزان p‌ کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: اگرچه از نظر میانگین شدت علائم کلی سندرم قبل از قاعدگی در بین دو گروه مریم گلی و دارونما قبل از درمان تفاوت معنی‌داری وجود داشت (۰۰۱/۰p<)، ولی اختلاف میانگین کاهش شدت کلی علائم بعد از دوره اول و دوم درمان معنی‌دار و نشان دهنده تأثیر بیشتر مریم گلی بود (۰۰۱/۰p<). در مورد کاهش شدت علائم روحی، بین دو گروه اختلاف معنی‌داری وجود داشت و مریم گلی مؤثرتر از دارونما بود (۰۰۱/۰p<).
نتیجه‌گیری: عصاره مریم گلی موجب کاهش شدّت علائم روانی این سندرم می‌شود و اثر آن نسبت به دارونما بیشتر می‌باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndrome

نویسندگان [English]

  • Roghayeh Abdnezhad 1
  • Masoumeh Simbar 2
  • Zohreh Sheikhan 3
  • Faraz Mojab 4
  • Malihe Nasiri 5
1 M.Sc. student in Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Professor, Department of Midwifery and Reproductive Health, Reproductive Endocrinology Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Instructor, Department of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Professor, Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5 Assistant professor, Department of Biostatistics, School of Paramedicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
چکیده [English]

Introduction: Premenstrual syndrome (PMS) is one of the most common psychosomatic disorders in women which significantly affects their social quality of life. Some studies have demonstrated the effects of Salvia on some problems of menstruation. Therefore, this study was performed with aim to investigate the effects of Salvia extract on the symptoms of PMS.
Methods: This randomized, triple-blind, clinical trial study was conducted on 90 students living in the dormitories of Shahid Beheshti University of Medical Sciences in 2015. After diagnosis by the standard form of PMS diagnosis, the samples were randomly assigned to two groups. They were treated for two consecutive months, since the 21st day of menstruation till the 5th day of next menstrual cycle with 500 mg sage capsule or placebo once a day. Data collection tools were questionnaire and the form of daily status recording of the symptoms. Data was analyzed by SPSS software (version 20) and t-test, Chi-square, Mann-Whitney, and repeated measurements tests. P<0.05 was considered significant.
Results: Although there was a significant difference between the two groups of sage and placebo in terms of overall severity of premenstrual syndrome symptoms before treatment (P<0.001), but the difference between the mean reduction in the overall severity of symptoms after the first and second stages of treatment was significant and showed the greater effect of sage (P<0.001). There was a significant difference between the two groups in reducing the severity of emotional symptoms, and sage was more effective than placebo (P <0.001).
Conclusion: Sage extract reduces the severity of emotional symptoms of PMS; it is more effective than placebo.

کلیدواژه‌ها [English]

  • Clinical trial
  • Emotional symptoms
  • Premenstrual Syndrome
  • Sage extract

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مجله زنان، مامایی و نازایی ایران
دوره 20، شماره 10
دی 1396
صفحه 84-94

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