نوع مقاله : اصیل پژوهشی
نویسندگان
1 دستیار گروه زنان و مامایی، مرکز پزشکی آموزشی-درمانی امام حسین (ع)، دانشکده پزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران
2 (1) دانشیار گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Introduction: Given the prevalence, significance, and high physical and psychological complications of urinary incontinence, as well as the need to identify more effective treatments for these patients, this study aimed to determine the efficacy of Solifenacin succinate in treating patients with mixed urinary incontinence.
Methods: In this randomized controlled clinical trial, 200 women with mixed urinary incontinence were selected based on inclusion criteria and through convenience sampling. They were randomly assigned using block randomization into two groups: the intervention group (100 participants: 5 mg oral solifenacin succinate once daily for three months) and the placebo group (100 participants). The severity of urinary incontinence was assessed using the standardized QUID questionnaire once before the study and then at 1.5 and 3 months after the study, with comparisons made between the two groups.
Results: In the intervention group compared to the control group, the QUID questionnaire scores were significantly lower at 1.5 months (6.65 ± 1.08 vs. 14.80 ± 2.52, p < 0.001) and at 3 months post-study (3.25 ± 1.11 vs. 9.98 ± 4.34, p < 0.001). The QUID scores, and consequently, the severity of urinary incontinence, decreased significantly more in the intervention group compared to the control group at 1.5 months post-study (-8.47 ± 2.94 vs. -0.88 ± 1.42, p < 0.001) and at 3 months post-study (-11.87 ± 3.04 vs. -5.70 ± 4.24, p < 0.001).
Conclusion: It appears that Solifenacin succinate is an effective medication for the treatment of mixed urinary incontinence.
کلیدواژهها [English]
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