شیوع آنمی در سه ماهه اول، دوم و سوم بارداری در ایران- یک مطالعه مرور سیستماتیک و متاآنالیز

نوع مقاله: اصیل پژوهشی

نویسندگان

1 دانشیار گروه آمار حیاتی، مرکز تحقیقات پیشگیری از آسیب های روانی- اجتماعی، دانشکده پزشکی، دانشگاه علوم پزشکی ایلام، ایران.

2 کارشناس ارشد مرکز تحقیقات میکروب شناسی بالینی، دانشکده پزشکی، دانشگاه علوم پزشکی ایلام، ایلام، ایران.

3 دانشجوی پزشکی، کمیته تحقیقات دانشجویی، دانشکده پزشکی، دانشگاه علوم پزشکی ایلام، ایلام، ایران.

4 استادیار گروه قلب و عروق، دانشکده پزشکی، دانشگاه علوم پزشکی ایلام، ایلام، ایران ایران.

چکیده

مقدمه: کم خونی، یک مشکل بهداشتی شایع دوران بارداری در سراسر جهان است. مطالعات صورت گرفته در ایران، شیوع آنمی در سنین مختلف بارداری را متفاوت گزارش کرده اند و یک برآورد کلی از آن وجود ندارد، لذا مطالعه حاضر با هدف بررسی میزان شیوع کم خونی در زنان باردار ایرانی به روش مرور سیستماتیک و متاآنالیز انجام شد.
روش کار: این مطالعه مرور سیستماتیک بر اساس بانک های اطلاعاتی Magiran، Iran medex، SID، Medlib، IranDoc، Scopus، Pubmed، Science Direct، Cochrane، Embase، Web of Science، Springer، Online Library Wiley و همچنین موتور جستجوی Google Scholar در بازه زمانی 94-1370 و با استفاده از کلید واژه های استاندارد انجام شد. تمام مقالات مرور شده که دارای معیار ورود به مطالعه بودند، مورد بررسی قرار گرفتند. به منظور ترکیب نتایج مطالعات از مدل اثرات تصادفی به روش متاآنالیز استفاده شد. داده ها با استفاده از نرم افزار Stata (نسخه 1/11) آنالیز شدند. میزان p کمتر از 05/0 معنی دار در نظر گرفته شد.
یافته ها: در مرور سیستماتیک تعداد 12 مقاله با حجم نمونه 7087 نفر وارد فرآیند متآنالیز شدند. شیوع آنمی در سه ماهه اول 6/19% (فاصله اطمینان 95%: 9/30-4/8)، در سه ماهه دوم 1/10% (فاصله اطمینان 95%: 4/16-7/3) و در سه ماهه سوم بارداری 1/16% (فاصله اطمینان 95%: 22-2/10) برآورد شد.
نتیجه گیری: شیوع آنمی در سه ماهه اول بارداری بیش از سه ماهه دوم و سوم می باشد که نشان می دهد زنان باردار در سه ماهه اول بارداری نیازمند مراقبت های بیشتری از جمله تغذیه مناسب و دریافت مکمل آهن و فولیک اسید هستند.
 

کلیدواژه‌ها


عنوان مقاله [English]

The Prevalence of Anemia in First, Second and Third Trimester of Pregnancy in Iran: a systematic review and Meta-analysis

نویسندگان [English]

  • Kourosh Sayehmiri 1
  • Zahra Darvishi 2
  • Milad Azami 3
  • Samiramis Qavam 4
1 Associate Professor, Department of Biostatistics, Prevention of Psychosocial Impairment
2 Clinical Microbiology Research Center, Ilam University of Medical Sciences , Ilam, Iran
3 Medical Student, Student Research Committee, Ilam University of Medical Sciences , Ilam, Iran
4 Department of Cardiology, School of Medicine, Ilam University of Medical Sciences , Ilam,iran
چکیده [English]

Introduction: Anemia is a common health problem during pregnancy worldwide. The studies performed in Iran have reported different prevalence of anemia in various gestational age, and there is no overall estimate of it. This study was performed with aim to evaluate the prevalence of anemia in Iranian pregnant women by systematic review and Meta-analysis method.
Methods: This systematic review study was performed based on information databases of Magiran, Iran medex, SID, Medlib, IranDoc, Scopus, Pubmed, Science Direct, Cochrane, Embase, Web of Science, Springer, Online Library Wiley and also search engine of Google Scholar using standard key words from 1991 to 2015. All reviewed papers which had inclusion criteria were evaluated. Random effect model by meta-analysis method was used to combine the studies' results. Data was analyzed using Stata software (Version 11.1). PResults: In systematic review, 12 studies with sample volume of 7087 pregnant woman were entered to the meta-analysis. The prevalence of anemia in first, second, and third trimester of pregnancy was estimated 19.6% (CI: 95%, 8.4-30.9), 10.1% (CI: 95%, 3.7-16.4) and 16.1% (CI: 95%, 10.2-22), respectively.
Conclusion: The prevalence of anemia in first trimester of pregnancy is more than second and third trimester. This shows that pregnant women require more care including proper nutrition and supplements of iron and folic acid during first trimester of pregnancy.

کلیدواژه‌ها [English]

  • Anemia
  • Iran
  • Meta-analysis
  • Pregnancy trimester
  • Pregnant Women
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