کیفیت خواب و پره اکلامپسی: یک مطالعه مورد-شاهدی

نوع مقاله: اصیل پژوهشی

نویسندگان

1 استادیار گروه مامایی، مرکز تحقیقات مراقبت مبتنی بر شواهد، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

3 استادیار گروه بیماری های مغز و اعصاب، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

4 دانشیار گروه زنان و مامایی، مرکز تحقیقات سلامت زنان، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

5 مربی گروه پرستاری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: پره اکلامپسی یک عارضه شایع و خطرناک حاملگی با علت ناشناخته است. التهاب سیستمیک و استرس اکسیداتیو متعاقب اختلال خواب ممکن است باعث افزایش فشار خون شود. مطالعه حاضر با هدف تعیین ارتباط کیفیت خواب با پره اکلامپسی انجام شد.
روش کار: این مطالعه مورد شاهدی در سال 1393 بر روی 150 زن باردار مبتلا به پره اکلامپسی و 150 زن سالم مراجعه کننده به مراکز بهداشتی- درمانی و بیمارستان های دانشگاهی شهر مشهد انجام گرفت. ابزار گردآوری داده ها فرم اطلاعات مربوط به مشخصات فردی، علائم بالینی و آزمایشگاهی پره اکلامپسی، مقیاس افسردگی، اضطراب، استرس (دس 21) و پرسشنامه کیفیت خواب پیتزبرگ بود. کیفیت نامناسب خواب، به صورت نمره بیشتر از 5 حاصل از پرسشنامه پیتزبرگ و پره اکلامپسی با فشارخون سیستولی مساوی یا بیشتر از 140 میلی متر جیوه و یا فشار خون دیاستولی مساوی یا بیشتر از 90 میلی متر جیوه همراه با دفع ادراری پروتئین به میزان 300 میلی گرم در ادرار 24 ساعته و یا مساوی یا بیش از +1 در تست نواری تعریف شد. تجزیه و تحلیل داده ها با استفاده از نرم افزار آماری SPSS (نسخه 16) و از آزمون های آماری تی مستقل، من ویتنی،کای دو و مدل رگرسیون لوجستیک انجام شد. میزان p کمتر از 05/0 معنی دار در نظر گرفته شد.
یافته ها: بین کیفیت خواب با پره اکلامپسی ارتباط معنی داری وجود داشت (001/0p<)؛ به طوری که 119 نفر (3/79%) از افراد مبتلا به پره اکلامپسی و نیز 91 نفر (7/60%) از افراد سالم کیفیت خواب نامناسب داشتند و احتمال ابتلاء به پره اکلامپسی در صورت وجود کیفیت نامناسب خواب 48/2 برابر بود (49/1-15/4: 95%، 48/2=OR).
نتیجه گیری: کیفیت نامناسب خواب زمینه ساز بروز پره اکلامپسی است، لذا غربالگری کیفیت خواب توسط ارائه دهندگان مراقبت های بارداری توصیه می شود.

کلیدواژه‌ها


عنوان مقاله [English]

Sleep quality and preeclampsia: a case-control study

نویسندگان [English]

  • Masoumeh Kordi 1
  • Azra vahed 2
  • Fariborz Rezaeitalab 3
  • Marzieh lotfalizade 4
  • Seyed Reza Mazlom 5
1 Assistant Professor, Department of Midwifery, Patient Safety and Health Quality Research Center , School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
2 M.Sc. Student, Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
3 Assistant Professor, Department of Neurological Diseases, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Associate Professor, Department of Obstetrics and Gynecology, Women's Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
5 Instructor of Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction: Preeclampsia is the most common and dangerous complication of pregnancy with unknown cause. Systemic inflammation and oxidative stress following sleep disorders may cause increased blood pressure. This study was performed with aim to determine the relationship between sleep quality and preeclampsia.
Methods: This case-control study was conducted on 15 pregnant women with preeclampsia and 150 healthy women, referred to health centers and academic hospitals of Mashhad city in 2014. Data collection tools included information form related to demographic characteristics, clinical and laboratory signs of preeclampsia, depression, anxiety, stress (DAS 21) questionnaire, and Pittsburgh Sleep Quality Index (PSQI). Poor sleep quality was defined as a score >5 from PSQI, preeclampsia was defined as systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg accompanied with 24 hours urinary protein excretion > 300 mg, or more than + 1 in the strip. Data was analyzed using SPSS software (version 16), and independent t-test, Mann-Whitney, Chi-square test, and logistic regression model. PResults: There was significant relationship between poor sleep quality and preeclampsia (P<0.001), so that, 119 (79.3%) of preeclamptic patients and 91 (60.7%) of healthy cases had poor sleep quality, and risk of preeclampsia in case of poor sleep quality was 2.48 times more (OR=2.48, %95:4.15-1.49).
Conclusion: Poor sleep quality is predispose of preeclampsia. Thus, sleep quality screening by pregnancy care providers is recommended.

کلیدواژه‌ها [English]

  • Blood pressure disorders
  • Preeclampsia
  • Sleep disorders in pregnancy
  • Sleep Quality
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