مقایسه سطح سرمی ویتامین D پس از ماستکتومی در زنان با و بدون عفونت پس از جراحی: مطالعه مورد-شاهدی

نوع مقاله: اصیل پژوهشی

نویسندگان

1 استادیار گروه جراحی عمومی، دانشکده پزشکی، دانشگاه علوم پزشکی تبریز، تبریز، ایران.

2 استادیار گروه بیماری‌های عفونی، دانشکده پزشکی، دانشگاه علوم پزشکی تبریز، تبریز، ایران.

10.22038/ijogi.2020.15995

چکیده

مقدمه: ابتلاء به عفونت پس از ماستکتومی می­تواند طول مدت بهبودی را به‌شدت افزایش دهد. با توجه به احتمال نقش ویتامین D در جلوگیری از ابتلاء به عفونت، مطالعه حاضر با هدف بررسی مقایسه سطح سرمی ویتامین D پس از ماستکتومی در زنان با و بدون عفونت پس از جراحی انجام شد.
روش‌کار: این مطالعه مورد شاهدی در سال 97-1396 بر روی 50 زن پس از جراحی ماستکتومی در بیمارستان امام رضا تبریز انجام شد. اطلاعات جمعیت‌شناختی و سطوح ویتامین D (اخذ نمونه خون) در ابزار محقق ساخته که حاوی اطلاعات مرتبط با بیماری بود، وارد شدند. تجزیه و تحلیل داده­ها با استفاده از نرم‌افزار آماری SPSS (نسخه 20) و آزمون­های آماری تی مستقل و کای دو انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: میانگین ویتامین D در گروه دارای عفونت 41/2±33/27 و در گروه بدون عفونت 11/4±55/49 بود (004/0=p). همچنین اکثر افراد گروه دارای عفونت (48%) در سطح کمبود ویتامین D بودند، در حالی که اکثر افراد گروه بدون عفونت (60%) در سطح نرمال قرار داشتند که این اختلاف از نظر آماری معنادار بود (003/0=p).
نتیجه‌گیری: سطوح پایین ویتامین D موجب افزایش احتمال ابتلاء به عفونت پس از ماستکتومی در زنان مبتلا به سرطان می‌شود.

کلیدواژه‌ها


عنوان مقاله [English]

Comparison of serum levels of vitamin D after mastectomy in women with and without postoperative infection: case-control study

نویسندگان [English]

  • Farshad Mahdavi 1
  • Hamid Owaysee Osquee 2
1 Assistant Professor, Department of General Surgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Assistant Professor, Department of Infectious Diseases, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
چکیده [English]

Introduction: Post-mastectomy infection can dramatically increase the duration of recovery. Considering the potential role of vitamin D in preventing infection, this study was performed with aim to compare serum levels of post-mastectomy vitamin D in women with and without postoperative infection.
Methods: This case-control study was performed on 50 women after mastectomy at Tabriz Imam Reza Hospital in 2017-2018. Demographic information and vitamin D levels (taking blood samples) were included in a researcher-made instrument containing disease-related information. Data were analyzed by SPSS software (version 20) and independent t-test and Chi-square tests. P< 0.05 was considered statistically significant.
Results: The mean of vitamin D in the infected group was 27.33 ±2.41 and in the uninfected group was 49.55±4.11 (p=0.004). Also, most patients in the infected group (48%) had vitamin D deficiency, while most subjects in the uninfected group (60%) had normal vitamin D that the difference between the two groups was significant (p=0.003).
Conclusion: Low levels of vitamin D increase the risk of infection after mastectomy in women with cancer.

کلیدواژه‌ها [English]

  • Breast Cancer
  • Infection
  • Mastectomy
  • Vitamin D
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