گیاهان دارویی دارای عوارض سوء در بارداری- یک مطالعه مروری مبتنی بر شواهد

نوع مقاله: مروری

نویسندگان

استادیار گروه علوم پایه، دانشکده علوم پزشکی اسفراین، اسفراین، ایران.

چکیده

مقدمه: در کنار اثرات زودگذر درمانی، برخی گیاهان دارویی دارای اثرات جبران‌ناپذیر بر روی تکامل دوره بارداری و رشد جنینی می­باشند؛ به‌طوری‌که امروزه استفاده از گیاهان دارویی از نکات مورد سؤال در جوامع محسوب می­شود. استفاده از ترکیبات گیاهان دارویی نیازمند آگاهی و اتخاذ استانداردهای مصرف در زنان باردار می­باشد، لذا مطالعه مروری حاضر با هدف بررسی اثرات سوء برخی گیاهان دارویی بر روی بارداری انجام شد.
روش‌کار: در این مطالعه مروری مقالات مربوط به اثرات سوء گزارش شده گیاهان دارویی بر روی مادران باردار از پایگاه­های اطلاعاتی علمی نظیر SID، Google Scholar، Scopus، Iran Medex، ISC، ISI، MedLib، PubMed  و Chemical abstract و با استفاده از کلمات کلیدی ضروری گیاهان دارویی، بارداری، سقط، عوارض جانبی جستجو شدند. در نهایت 60 مقاله که از نظر موضوعی مناسب‌تر از سایر مقالات بودند، مورد بررسی قرار گرفتند. جستجوی مقالات بدون محدودیت زمانی و به زبان‌های انگلیسی و فارسی انجام شد.
یافته‌ها: از میان گیاهان دارویی مطالعه شده علف هفت بند، مرزنجوش، رازیانه، گل گاوزبان، گیاه پنج انگشت، کوهوش آبی، منتانوا تمنتسا و تریپتریگوم ویلفردی اثرات سمی و تراتوژنیک بر روی جنین داشتند. جنسه، آنژلیک چینی و تخم شوید با تأثیر بر میزان هورمون‌های قاعدگی باعث القاء قاعدگی، روغن‌های کرچک و گل مغربی موجب افزایش انقباضات رحمی و پونه موجب از دست رفتن ریتم رحمی و افزایش خطر سقط می­شوند.
نتیجه‌گیری: با توجه به نتایج مطالعه حاضر وجود اثرات جانبی برخی از گیاهان دارویی توصیه می­شود مصرف یا عدم مصرف این گیاهان با نظر پزشک صورت پذیرد.

کلیدواژه‌ها


عنوان مقاله [English]

Medicinal herbs with side effects during pregnancy- An evidence-based review article

نویسندگان [English]

  • Mahdi Esmaeilzadeh
  • Bagher Moradi
Assistant professor, Department of Basic Sciences, Faculty of Medical Sciences, Esfarayen, Iran.
چکیده [English]

Introduction: Beside the therapeutic effects, somer medicinal herbs have side effects on pregnancy development and embryonic growth, so that today, the use of medicinal herbs is considered as an important question in communities. The use of medicinal herbs requires awareness and consumption standards in pregnant women. Therefore, this study was performed with aim to examine the side effects of some medicinal herbs on pregnancy.
Methods: In this review article, the studies related to the side effects of medicinal herbs on pregnant women were searched from scientific databases such as SID،Google Scholar،Scopus Iran Medex،ISC،ISI،MedLib and by the keywords of Medicinal herb, Abortion, Pregnancy and Side effects without time limitation in English and Persian languages.
Results: Among the studied medicinal herbs, Polygonum, Origanum marjorana, multiflorum, Echium, Foeniculum vulgare, Vitex agnus castus, Blue cohosh, Montanoa tomentosa and Tripterygium wilfordii had teratogenic and toxic effects on embryo. Ginseng, Dong quai, Anethum graveolens.L induce menstruation by affecting on menstruation hormones, Castor oil and Evening primrose oil induce uterine contraction and Mentha pulegium increases risk of abortion.
Conclusions: According to the present study, some medicinal herbs have side effects on pregnancy, so it is recommended that these herbs be used by the physician's advice.

کلیدواژه‌ها [English]

  • Abortion
  • Medicinal herb
  • pregnancy
  • Side effects
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