بررسی تأثیر پماد آلفا (فاندرمول) بر بهبود زخم اپی‌زیاتومی در زنان نخست‌زا

نوع مقاله: اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 مربی گروه مامایی، مرکز تحقیقات مراقبت مبتنی بر شواهد، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

3 دانشیار گروه فارماکولوژی، دانشکده داروسازی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

4 استاد گروه آمار، مرکز تحقیقات نوزادان، دانشکده بهداشت، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

5 استادیار گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: اپی‌زیاتومی شایع‌ترین مداخله جراحی در زایمان است. پماد آلفا با رگ‌زایی در منطقه آسیب دیده و کاهش التهاب و جلوگیری از گسترش عفونت، اثرات ترمیمی خود را اعمال می‌کند، لذا مطالعه حاضر با هدف بررسی اثر پماد آلفا بر بهبود زخم اپی‌زیاتومی انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی دوسوکور در سال ۹۵-۱۳۹۴ بر روی ۷۰ زن نخست‌زا در بیمارستان ام البنین (س) مشهد انجام شد. واحدهای پژوهش (۳۵ نفر مداخله و ۳۵ نفر کنترل) از 48 ساعت بعد از زایمان، روزانه 1 بار به مدت 10 روز، یک بند انگشت از پماد تجویز شده (آلفا یا دارونما) را پس از شستشوی محل زخم با نرمال سالین و خشک شدن استفاده ­کردند. بهبود زخم با استفاده از مقیاس ریدا در روزهای اول، پنجم و دهم پس از زایمان ارزیابی شد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 16) و آزمون‌های من ویتنی، تی تست، کای دو و فیشر انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: بهبود زخم در روز اول (976/0=p)، پنجم (9/0=p) و دهم (931/0=p) بعد از زایمان بین دو گروه اختلاف معناداری نداشت.
نتیجه‌گیری: مصرف پماد آلفا تأثیری در بهبودی زخم اپی‌زیاتومی ندارد.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of alpha ointment (fundermol) on episiotomy wound healing in primiparous women

نویسندگان [English]

  • Mozhdeh Navi Nezhad 1
  • Zahra Abedian 2
  • Javad Asili 3
  • Habibollah Esmaeili 4
  • Atiyeh Vatanchi 5
1 M.Sc. student in Midwifery, Student Research Committee, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Instructor, Department of Midwifery, Evidence-based Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
3 Associate Professor, Department of Pharmacology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Professor, Department of Statistics, Neonates' Research Center, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
5 Assistant Professor, Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction: Episiotomy is the most common surgical intervention in delivery. Alpha ointment exerts its restorative effects by angiogenesis of the injured area, reducing inflammation and preventing the spread of infection. Therefore, this study was performed with aim to evaluate the effect of Alpha ointment on episiotomy wound healing.
Methods: This double-blind clinical trial was performed on 70 primiparous women in Mashhad Omolbanin Hospital during 2015-2016. The research units (35 in the intervention group and 35 in the control group), 48 hours after delivery once a day for ten days, used a knuckle of the prescribed ointment (Alpha or placebo) after washing and drying the wound with normal saline. Wound healing was evaluated using the REEDA scale on the first, fifth and tenth days after delivery. Data analysis was carried out by SPSS statistical software (version 16), and using Mann-Whitney, T-test, Chi-square and Fisher tests. P<0.05 was considered significant.
Results: There was no significant difference between two groups in terms of wound healing on the first day (P = 0.976), fifth day (P=0.9), and tenth day (P=0.931).
Conclusion: Using Alpha ointment has no effect on episiotomy wound healing.

کلیدواژه‌ها [English]

  • Alpha ointment
  • Delivery
  • Episiotomy
  • Wound healing
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