تأثیر دو شیوه زندگی فعال و غیر فعال همراه با رژیم غذایی کنترل شده بر مقاومت انسولینی و سطوح سرمی آنزیم‌های AST و ALT کبد زنان باردار

نوع مقاله: اصیل پژوهشی

نویسندگان

1 کارشناس ارشد فیزیولوژی، دانشگاه آزاد اسلامی واحد نجف آباد، نجف آباد، ایران.

2 دانشیار گروه تربیت بدنی و علوم ورزشی، دانشگاه آزاد اسلامی واحد نجف آباد، نجف آباد، ایران.

چکیده

مقدمه: با توجه به اثرات مفید تأیید شده فعالیت بدنی در دوران بارداری، مطالعه حاضر با هدف بررسی زندگی فعال و غیرفعال بر سطوح مقاومت به انسولین و آنزیم‌های AST و ALT کبدی زنان باردار سه ماهه دوم بارداری انجام شد.
روش‌کار: این مطالعه مقطعی در سال 1394 بر روی80 زن باردار سه ماهه دوم شهرستان اصفهان انجام شد. افراد پس از تکمیل فرم رضایت نامه و پرسشنامه فعالیت بدنی دوران بارداری PPAQ بر اساس سبک زندگی و انجام و عدم انجام پیاده‌روی روزانه به دو گروه فعال و غیرفعال تقسیم و از نظر سطوح سرمی آنزیمهای AST و ALT کبدی و میزان مقاومت به انسولین مقایسه شدند. تجزیه و تحلیل داده ها با استفاده از نرم‌افزار آماری SPSS (نسخه 18) و آزمون کولموگروف اسمیرنوف و تی مستقل انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: نتایج مطالعه نشان داد که سطح سرمی آنزیم AST کبدی در زنان باردار فعال که پیاده‌روی روزانه داشتند به طور معنی‌داری کمتر از زنان غیرفعال بود (018/0=p). ولی در میزان سطح ALT (079/0=p) و مقاومت به انسولین (146/0=p) تفاوت معناداری مشاهده نشد.
نتیجه‌گیری: فعالیت بدنی در دوران بارداری بر سطح سرمی آنزیم AST کبدی تأثیر دارد، ولی دلیل عدم معناداری سطوح آنزیم ALT کبدی و مقاومت به انسولین را با توجه به بررسی متغیرهای کنترل می‌توان پیاده‌روی با سرعت آهسته، ساعات بی‌تحرکی طولانی مدت (5/2±8/11) و خواب طولانی‌تر از استاندارد (00/2±9/9) بیان نمود.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of two passive and active lifestyle along with controlled diet on insulin resistance and serum levels of AST and ALT liver enzyme in pregnant women

نویسندگان [English]

  • Somayeh Sheikhi dehchenari 1
  • Jamshid Banaee Boroujeni 2
1 MSc of Physiology, Islamic Azad University, Najaf Abad Branch, Najaf Abad, Iran.
2 Associate professor, Department of Physical Education and Sports Sciences, Islamic Azad University, Najaf Abad Branch, Najaf Abad, Iran
چکیده [English]

Abstract
Introduction: According to confirmed beneficial effects of physical activity during pregnancy, this study was performed with aim to investigate active and passive lifestyle on insulin resistance and the levels of AST and ALT liver enzymes in pregnant women at second trimester of pregnancy.
Methods: This cross-sectional study was performed on 80 pregnant women at second trimester in Isfahan at 2015. After completing the consent form and Pregnancy Physical Activity Questionnaire (PPAQ) based on lifestyle and doing and not doing daily walking were divided to two groups of active and passive lifestyle and were compared in terms of insulin resistance and the levels of AST and ALT liver enzymes. Data was analyzed using SPSS software (version 18) and Kolmogorov-Smirnov test and t-test. PResults: Serum levels of AST liver enzymes in active pregnant women who had daily walk were significantly lower than inactive women (P=0.018), but there was no significant difference between two groups in terms of ALT levels (P=0.079) and insulin resistance (P=0.146).
Conclusion: Physical activity during pregnancy is effective on serum levels of AST liver enzymes, but according to the evaluation of control variables, ALT liver enzyme levels and insulin resistance were not significantly different due to walking with slow speed, long hours of immobility (11.8 ± 2.5)  and sleep longer than the standard (9.9 ± 2.00).

کلیدواژه‌ها [English]

  • Alanine transaminase
  • Aspartate Aminotransferase
  • insulin resistance
  • pregnancy
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