مروری سیستماتیک بر انواع روش‌های درمانی مؤثر بر خونریزی پس از زایمان در ایران و جهان

نوع مقاله: مروری

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران

2 استادیار گروه مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران

4 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

چکیده

مقدمه: خونریزی پس از زایمان به عنوان اولین علت مرگ و میر مادری در کشورهای در حال توسعه است. با توجه به اینکه پیشگیری و درمان خونریزی پس از زایمان گامی مهم در سلامت جامعه و به خصوص سلامت زنان است، مطالعات متفاوتی در جهت درمان مؤثر بر خونریزی پس از زایمان انجام شده است. مطالعه حاضر با هدف مروری سیستماتیک بر مطالعات انجام شده در مورد درمان‌های طبی و غیرطبی مؤثر بر خونریزی پس از زایمان در ایران و جهان انجام شد.
روش‌کار: در این مطالعه مروری سیستماتیک اطلاعات مورد نظر از پایگاه‌های اطلاعاتی مرکز ثبت کارآزمایی‌های بالینی IRCT، Google Scholar، SID، Pubmed، Scopus و Science Direct با کلمات کلیدی خونریزی پس از زایمان و کارآزمایی بالینی در بازه زمانی 2015-2000 جستجو شد. بر اساس معیار جداد، مطالعاتی که نمره 3 و یا بیشتر گرفتند وارد مطالعه شدند. تجزیه و تحلیل داده‌ها به صورت کیفی انجام شد.
یافته‌ها: در نهایت 67 کارآزمایی شامل 18 مقاله ایرانی و 49 مقاله خارجی که دارای معیار ورود به مطالعه بودند، بررسی شدند. بر اساس بررسی‌های انجام شده، تعداد مطالعات انجام شده در زمینه داروهای گیاهی بسیار محدود اما در زمینه داروهای شیمیایی متعدد بود.
نتیجه‌گیری: نتایج نشان داد که اکسی توسین به علت عوارض جانبی کمتر به عنوان اولین خط درمان خونریزی پس از زایمان مورد استفاده قرار می‌گیرد و داروی بعدی میزوپروستول است. در مورد تأثیر داروهای دیگر چه طبی و چه غیر طبی نیاز به انجام مطالعات بیشتر است.

کلیدواژه‌ها


عنوان مقاله [English]

Systematic review on variety of effective treatment methods for postpartum hemorrhage in Iran and world

نویسندگان [English]

  • Sahar Ghalandari 1
  • Nourossadat Kariman 2
  • Zohreh Sheikhan 3
  • Hadis Shahrahmani 1
  • Nayereh Asadi 4
1 M.Sc. student of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Assistant Professor, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 M.Sc. of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 M.Sc. student of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Postpartum hemorrhage (PPH) is the first cause of maternal mortality and morbidity in developing countries. Since treatment and prevention of postpartum hemorrhage is an essential step in the health of community and specially the health of women, many studies have been conducted on the effective treatment of PPH. This study was performed with aim to systematically review the studies about the medicinal and non-medicinal treatments of PPH in Iran and the world.
Methods: In this systematic review, the information was searched from databases of IRCT, Google Scholar, SID, Scopus, Pubmed and Science Direct with keywords of postpartum hemorrhage and clinical trial during 2000 to 2015. Then, the articles which obtained the score of ≥ 3 based on Jadad criteria were entered to the study. Data were analyzed qualitatively.
Results: Finally, 67 clinical trials involving 18 Iranian and 49 foreign articles which met inclusion criteria were investigated. Investigations indicated that there are very limited studies on herbal treatments while the studies on chemical treatments were numerous.
Conclusion: The results showed that oxytocin is the first line treatment used in PPH due to its less side effects and the next drug is misoprostol. Further studies are needed to clarify the effect of other drugs.

کلیدواژه‌ها [English]

  • Clinical trial
  • Postpartum Hemorrhage
  • Systematic review
  • Treatment
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