مروری بر داروهای گیاهی مؤثر بر سندرم پیش از قاعدگی در ایران

نوع مقاله: گزارش مورد

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی تهران، تهران، ایران.

2 دانشیار گروه مامایی و بهداشت باروری، مرکز تحقیقات آندوکرینولوژی تولید مثل، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

چکیده

مقدمه: سندرم پیش از قاعدگی، یکی از شایع‌ترین اختلالات سنین باروری است که زنان برای رها شدن از آن به درمان‌های طبیعی یا طب مکمل روی می‌آورند. ارائه‌دهندگان سلامت در راستای کمک به زنان در جهت تصمیم‌گیری مناسب برای انتخاب بهترین درمان جایگزین و مبتنی بر شواهد، به اطلاعات با کیفیت و مناسب نیاز دارند.مطالعه حاضر با هدف بررسی کارآزمایی‌های بالینی انجام شده در ارتباط با داروهای گیاهی و جایگزین برای درمان سندرم پیش از قاعدگی در ایران و تحلیل اثربخشی آن‌ها در کاهش شدت علائم سندرم قبل از قاعدگی انجام شد.
روش کار: در این مطالعه تعداد ۴۲ کار‌آزمایی بالینی به طریق جستجو در پایگاه‌های الکترونیکی SID، Pubmed، Google scholar و Science direct و همچنین جستجوی دستی در کتاب و پایان‌نامه‌های دانشجویی از بهمن ماه سال ۱۳۹۳ با استفاده از کلمات کلیدی سندرم پیش از قاعدگی، داروهای گیاهی و طب مکمل و واژه‌های لاتین Premenstrual syndrome، PMS، herbal medicine، complementary medicine و alternative medicine یافت شد. مقالات انگلیسی زبان از سال ۲۰۰۵ تا ۲۰۱۶ و مقالات فارسی از سال ۱۳۸۹ به بعد مورد بررسی قرار گرفتند.
یافته ها: در این مطالعه تعداد ۱۱ نوع مختلف گیاهان دارویی در ۴۲ مطالعه کارآزمایی بالینی که دارای معیار ورود به مطالعه بودند مورد بررسی قرار گرفتند. اکثر گیاهان دارویی بررسی شده در مقالات دارای ترکیبات آنتی اکسیدانی، فلاونوئیدی با خاصیت ضد التهاب و ضد درد بوده و در تسکین علائم PMS تأثیر مطلوبی داشتند. اکثریت این گیاهان فاقد عوارض جانبی یا دارای حداقل عوارض بودند، به دلیل اینکه متدولوژی مطالعات از نظر کیفیت ناهمگون بود، لذا امکان انجام متاآنالیز وجود نداشت.
نتیجه‌گیری: نتایج مطالعات نشان‌دهنده کاهش شدت علائم سندرم پیش از قاعدگی با استفاده از داروهای گیاهی چون ویتاگنوس، گل‌مغربی، بابونه، جوانه گندم، اسطوخودوس، خوشاریزه، سنبل الطیب، اسانس پوست پرتقال و زنجبیل بود.

کلیدواژه‌ها


عنوان مقاله [English]

A review on herbal medicines effective of premenstrual syndrome in Iran

نویسندگان [English]

  • Roghayeh Abdnejad 1
  • Masoomeh Simbar 2
1 M.Sc. student of Midwifery, School of Nursing and Midwifery, Tehran Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Associate professor, Department of Midwifery and Reproductive Health, Reproduction Endocrinology Research Center, School of Nursing and Midwifery, Tehran Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Premenstrual syndrome is one of the most common disorder of reproductive age. Women turns to natural remedies or complementary medicine to get rid of it. Health providers need to appropriate information in order to help women to choose the best alternative based on evidences. This study was performed with aim to evaluate the clinical trials which are performed about herbal and alternative remedies for treatment of premenstrual syndrome in Iran and the analysis of their effectiveness on reducing the symptoms of premenstrual syndrome.
Methods: In this study, 42 clinical trials were found through searching in electronic databases of SID, PubMed, Google scholar, Science direct and also searching in books and student thesis from February 2014 and using the key words including; Alternative medicine, Herbal medicine, Premenstrual syndrome, PMS, and Complementary medicine. The English articles from 2005 to 2016 and the Persian ones from 2010 were studied.
Results: In this study, 11 different types of medicinal plants in 42 clinical trials which met the inclusion criteria were evaluated. Most herbs have been studied in articles antioxidant compounds, flavonoids with anti-inflammatory and analgesic properties and had a favorable impact in relieving PMS. Most of the plants had antioxidant compounds, flavonoids with anti-inflammation and anti-pain characteristics and were effective in relieving the symptoms of PMS. Most of these plants had any side-effects or had minimal complications. Since the methodology of the studies were heterogeneous in terms of quality, so there was no possibility of conducting meta-analysis.
Conclusion: The results of studies indicate the reduction in the severity of premenstrual syndrome symptoms using herbal medicines such as Vitagnus, Evening Primrose oil, chamomile, wheat germ, lavender, Echinophora-platyloba, valerian, orange peel and ginger.

کلیدواژه‌ها [English]

  • Alternative Medicine
  • Clinical Trials
  • Herbal Medicine
  • Premenstrual Syndrome
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