عنوان مقاله [English]
نویسندگان [English]چکیده [English]
Objective: Breast cancer is a fatal disease that annually causes morbidity and mortality in hundreds of thousands of women worldwide. It seems that its prevalence is increasing in the north area, there has not been comprehensive information related to it this area yet. The main goal of this study is natural statistical determination of this study on the patients referred to our center.
Method: The radiotherapy- Oncology unit of this center is a referral center of four provinces Mazandaran, Gilan, Semnan and Golestan that undertake the follow up of patients after treatment. This study is a 5 year assessment (1379-1383) that has been performed on all patients referred to this center (totally 403 cases).
Results:Breast cancer at the rate of 24.9% was the most prevalent cancer in women referred to this center. Also, the trend showed that cancer increas in that period. Incidence dependency on age showed an increase of disease in the middle of the third decade (35 years old) to the end of the fourth decade (49 years old) and then showed a decreasing behavior. Detecting the breast mass was the most prevalent (94.1%) symptom for referring to the doctor. Also the most prevalent site involved was the upper external quarter (54.6%) of the left breast (52.8%). Staging of the disease manifested that 42.5% of the patients were at stage 3. The most common morphologic pattern (87.4%) was ductal invasive carcinoma, and the most common pathology associated was fibrocystic change. Concerning TNM classification, tumor size in the majority of cases (38.3%) was T2 (2-5 cm), 60% in position N1, and 7.2% of them have metastasis. It this study prevalence of the breast cancer during pregnancy was 1.2% and it’s prevalence in men 1.7%. Also there is bilateral involvement of the breast in 3.2% of the cases. There is significant relation between tumor size with lymph node involvement and also between lymph node involvements with metastasis. But there is no significant relation between disease stage and age.
Conclusion:Disease age in our patients was much less than common age in the publications. However, new methods are developing for primary prevention of breast cancer today. Also, considering disease stage at the time of referrial was higher at stage 3 in half of patients, thereby introduce approaches for ideal achievement of women to diagnostic programs for screening of breast cancer is the primary and principal women rights.