هپاتیت ویروسی در حاملگی

نوع مقاله: گزارش مورد

نویسندگان

1 دانشیار بیماری های عفونی وگرمسیری، دانشگاه علوم پزشکی شهید صدوقی یزد، یزد، ایران

2 استادیار آسیب شناسی، دانشگاه علوم پزشکی شهید صدوقی یزد، یزد، ایران.

3 دانشیار بیماری های داخلی، دانشگاه علوم پزشکی شهید صدوقی یزد، یزد، ایران

4 متخصص بیماری های داخلی، دانشگاه علوم پزشکی شهید صدوقی یزد، یزد، ایران.

چکیده

معمولاً سیر بالینی عفونت با بیشتر ویروسهای عامل هپاتیت شامل ویروس هپاتیت A، Bو C در حاملگی تغییری نمی کند ولی اگر خانم حامله ای دچار هپاتیت E شود ممکن است علائم بالینی آن شدید تر از سایر افراد باشد. شانس انتقال ویروسهای هپاتیت از مادر به جنین در زمان حاملگی بستگی به نوع ویروس دارد برای مثال ویروس هپاتیت A بندرت در داخل رحم به جنین منتقل می شود اما درحین زایمان انتقال ممکن است اتفاق بیافتد. در حالیکه اگر مادر در انتهای حاملگی یا هنگام زایمان مبتلا به هپاتیت B شود تا 60% احتمال انتقال ویروس به نوزاد وجود دارد. احتمال انتقال هپاتیت E از مادر به کودک بین 3/33%، تا 50% گزارش شده است. شیردادن مادران مبتلا به هپاتیت A، C و E بلامانع است. در طی عفونت حاد مادر با ویروس هپاتیت B اگر به نوزاد واکسن هپاتیت B و ایمونوگلوبولین اختصاصی هپاتیت B تزریق شده باشد، شیردادن مادر خطر اضافی جهت انتقال ویروس به نوزاد محسوب نمی شود

کلیدواژه‌ها


عنوان مقاله [English]

Viral Hepatitis in Pregnancy

نویسندگان [English]

  • Jamshid Ayatollahi 1
  • Shokouh Taghipour Zahir 2
  • Mohammad Bagher Owlia 3
  • Seyed Mahdi Sajjadi 4
1 Associate Professor of Infectious Diseases and Tropical Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2 Assistant Professor of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3 Associate Professor of Internal Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
4 Internist Internal Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
چکیده [English]

The course of infection with most hepatitis viruses such as hepatitis A, B, and C is not affected by pregnancy; however, a more severe course of viral hepatitis in pregnancy has been observed in patients infected with hepatitis E virus. Rate of transmission of hepatitis viruses during pregnancy depends on the type of virus. For instance, intrauterine transmission of hepatitis A virus is very rare, but perinatal transmission could occur. Conversely 60% of pregnant women who acquire acute infection with hepatitis B virus at or near delivery will transmit the virus to their offspring. Mother to child transmission of hepatitis E virus has been reported about 33.3-50%. Breast-feeding is not contra-indicated in women infected with hepatitis A, E, or C. During acute infection with hepatitis B virus, breast-feeding poses no additional risk for transmission of the virus if appropriate immunoprophylaxis including hepatitis B immunoglobulin and hepatitis B vaccine is administered.

کلیدواژه‌ها [English]

  • pregnancy
  • Viral Hepatitis
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Hepatitis E
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