بررسی عوامل مرتبط با حاملگی خارج رحمی پاره شده: یک مطالعه مروری نظام‌مند

نوع مقاله : مروری

نویسندگان

1 استادیار گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی مازندران، ساری، ایران.

2 کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی مازندران، ساری، ایران.

چکیده

مقدمه: حاملگی خارج رحمی (EP) به لانه­ گزینی یک تخمک بارور شده در خارج از حفره رحم اطلاق می­ شود. حاملگی خارج رحمی پاره شده، علت اصلی مرگ‌و‌میر مادران در سه ماهه اول بارداری می­ باشد. مطالعه حاضر با هدف مروری نظام‌مند بر عوامل مرتبط با حاملگی خارج رحمی پاره شده انجام شد.
روش‌کار: مطالعه حاضر با روش مرور سیستماتیک بر اساس چک‌لیست PRISMA انجام شد. یک جستجوی گسترده در پایگاه­ های اطلاعاتی داخلی و خارجی شامل PubMed، Magiran، Web of Science، Scopus، SID و موتور جستجوی Google Scholar با استفاده از واژه ­های کلیدی استاندارد شده MESH شامل Extrauterine Pregnancy، Ectopic Pregnancies، Abdominal Pregnancy،Heterotopic Pregnancy، Ovarian Pregnancy، Tubal Pregnancy، Interstitial Pregnancy، Perforation، Rupture، Factors، Related Factors و همچنین معادل فارسی آن­ها شامل حاملگی خارج رحمی، حاملگی خارج رحمی پاره شده، پارگی و عوامل مرتبط و با همه ترکیبات احتمالی کلمات مهم، اصلی و حساس، از ابتدا تا 12 مارس 2023 صورت گرفت.
یافته ­ها: در مجموع، 10 مقاله از 624 مطالعه شامل 3475 زن باردار وارد مطالعه شدند. از این تعداد حدود 1351 نفر (38%)، حاملگی خارج رحمی پاره شده با میانگین سنی 62/5±1/30 سال داشتند. عواملی مانند میزان سطح هورمون β-hCG (5 مورد)، هفته ­های سن حاملگی (2 مورد) و سابقه حاملگی خارج رحمی (2 مورد) از عوامل مرتبط با حاملگی خارج رحمی پاره شده بودند.
نتیجه ­گیری: مطالعه حاضر نشان داد عواملی مانند مقدار β-hCG، سن، سابقه EP، سن حاملگی، سابقه بیماری­ های عفونی لگن PID و استفاده از داروهای ضد بارداری با حاملگی خارج رحمی پاره شده (REP) مرتبط می­باشند.

کلیدواژه‌ها

عنوان مقاله [English]

Factors associated with ruptured ectopic pregnancy: a systematic review

نویسندگان [English]

  • Saloumeh Peivandi 1
  • Ali Habibi 2
1 Assistant professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
2 Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
چکیده [English]

Introduction: ectopic pregnancy (EP) refers to implanting a fertilized egg outside the uterine cavity. A ruptured ectopic pregnancy is the main cause of maternal mortality in the first trimester of pregnancy. The present study was performed with aim to systematically review the factors related to ruptured ectopic pregnancy.
Methods: This systematic review study was conducted based on the PRISMA checklist. An extensive search was performed in the internal and external databases, including PubMed, Magiran, Web of Science, Scopus, SID, and Google Scholar search engine using the keywords extracted from Mesh, including Extrauterine Pregnancy, Ectopic Pregnancies, Abdominal Pregnancy, Heterotopic Pregnancy, Ovarian Pregnancy, Tubal Pregnancy, Interstitial Pregnancy, Perforation, Rupture, Factors, Related Factors and also their Persian equivalent with all possible and main combinations from the beginning to March 12, 2023.
Results: A total of 10 articles out of 624 studies, including 3475 pregnant women were included in the study. Of these, about 1351 people (38%) had a ruptured ectopic pregnancy with mean age of 30.1±5.62 years. Factors such as β-hCG hormone level (5 cases), gestational age weeks (2 cases), and history of ectopic pregnancy (2 cases) were among the factors related to ectopic pregnancy.
Conclusion: The present study showed that factors such as β-hCG level, age, history of EP, gestational age, history of pelvic infectious diseases (PID) and use of contraceptives are related to ruptured ectopic pregnancy (REP).

کلیدواژه‌ها [English]

  • Ectopic pregnancy
  • Related factors
  • Ruptured ectopic pregnancy
  • Systematic review

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مجله زنان، مامایی و نازایی ایران
دوره 26، شماره 7
مهر 1402
صفحه 70-79

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