بررسی تأثیر زعفران خوراکی بر عملکرد جنسی زنان یائسه: یک مطالعه کارآزمایی بالینی

نوع مقاله: اصیل پژوهشی

نویسندگان

1 مربی گروه مامایی، مرکز تحقیقات مراقبت سالمندی، دانشکده پزشکی، دانشگاه علوم پزشکی خراسان شمالی، بجنورد، ایران.

2 مربی گروه مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی خراسان شمالی، بجنورد، ایران.

3 کارشناس ارشد مشاوره مامایی، بیمارستان بنت‌الهدی، بجنورد، ایران.

4 استادیار گروه مامایی و بهداشت باروری، دانشکده پزشکی، دانشگاه علوم پزشکی خراسان شمالی، بجنورد، ایران.

5 کارشناس ارشد مامایی، بیمارستان بنت‌الهدی، بجنورد، ایران.

6 استادیار گروه زنان و مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی خراسان شمالی، بجنورد، ایران.

10.22038/ijogi.2020.15552

چکیده

مقدمه: عملکرد جنسی، بخشی از زندگی و رفتار انسانی است که اختلال آن در دوران بعد از یائسگی 72% است. زعفران به‌دلیل داشتن ترکیباتی از قبیل کروسین و سافرانال دارای اثر تحریک جنسی است. مطالعه حاضر با هدف تعیین تأثیر زعفران خوراکی بر عملکرد جنسی زنان یائسه انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی دوسوکور در سال 96-1395 بر روی 67 زن یائسه در شهر بجنورد انجام شد. زنان یائسه روزانه یک عدد کپسول زعفران یا دارونما به‌مدت 28 روز مصرف کردند. پرسشنامه عملکرد جنسی روزن قبل از مصرف کپسول و 4 هفته بعد از اتمام مداخله توسط واحدهای پژوهش تکمیل گردید. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 16) و آزمون‌های تی زوجی و تی مستقل انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته ها: میانگین نمرات عملکرد جنسی در گروه زعفران قبل از مصرف 7/8±5/13 و بعد از مصرف 6/7±8/18 بود که بر اساس نتایج آزمون تی زوجی، عملکرد جنسی بهبود یافته بود (001/0p<)، اما در گروه کنترل تغییری در عملکرد جنسی قبل و بعد از مداخله ایجاد نشده بود (563/0=p). در هیچ یک از واحد‌های پژوهش عارضه‌ای از زعفران مشاهده نگردید.
نتیجه‌گیری: با توجه به بهبود قابل توجه عملکرد جنسی با مصرف کپسول زعفران، توصیه می‌شود زعفران به‌عنوان مکمل خوراکی در دوران یائسگی استفاده شود.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of oral saffron on sexual function of postmenopausal women: a clinical trial study

نویسندگان [English]

  • Mahbubeh Tabatabaeichehr 1
  • Sakineh Nazari 2
  • Maryam Bagheri 2
  • Ida Niazi 3
  • Zohreh Abassi 4
  • Maryam Soltani 5
  • Kataneh Kazemi 6
  • Mahboubeh Ghorbani 2
1 Instructor, Department of Midwifery, Gerontological Care Research Center, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
2 Instructor, Department of Midwifery, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
3 M.Sc. of Midwifery Counseling, Bent Al Hoda Hospital, Bojnurd, Iran.
4 Assistant Professor, Department of Midwifery and Reproductive Health, Faculty of Medicine, North Khorasan University of Medical Sience, Bojnurd, Iran.
5 M.Sc. in Midwifery, Bent al Hoda Hospital, Bojnurd, Iran.
6 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
چکیده [English]

Introduction: Sexual function is a part of human behavior and life that the rate of sexual dysfunction disorder in post-menopausal period is 72%. Saffron has sexual stimulation effect due to its ingredients such as Crocin and Safranal. This study was performed with aim to evaluate the effect of oral saffron on sexual function of postmenopausal women.
Methods: This double-blind clinical trial was performed on 67 postmenopausal women in Bojnourd in 2016-2017. Eligible postmenopausal women daily received one saffron capsule or placebo for 28 days. Female Sexual Function Index was completed before using capsule and 4 consecutive weeks after the intervention. Data were analyzed by SPSS software (version 16) and paired t-test and independent t-test. P<0.05 was considered statistically significant.
Results: The mean sexual function scores in saffron group before and after using saffron were 13.5 ± 8.7 and 18.8 ± 7.6, respectively. The results of paired t-test showed that sexual function was improved (p< 0.001). But, in the control group, no change in sexual function was observed before and after the intervention (p= 0.563). There were no side effects about use of saffron in any of the research subjects
Conclusion: Due to the significant improvement in sexual function with the use of saffron capsules, it is recommended to use saffron as an oral supplement in post-menopausal period.

کلیدواژه‌ها [English]

  • Post-menopausal women
  • Oral Saffron
  • Sexual function
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