شیوع درد نوروپاتیک و عوامل مؤثر بر کیفیت خواب زنان مبتلا به سرطان پستان پس از رادیوتراپی

نوع مقاله: اصیل پژوهشی

نویسندگان

1 کارشناس ارشد پرستاری، مرکز تحقیقات سل و بیماری‌های ریوی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی تبریز، تبریز، ایران.

2 دانشجوی کارشناسی هوشبری، دانشکده پیراپزشکی، دانشگاه علوم پزشکی تبریز، تبریز، ایران.

3 متخصص زنان و زایمان، دانشکده پزشکی و پیراپزشکی، دانشگاه علوم پزشکی اردبیل، اردبیل، ایران.

4 فلوشیپ انکولوژی زنان، دانشکده پزشکی و پیراپزشکی، دانشگاه علوم پزشکی اردبیل، اردبیل، ایران

چکیده

مقدمه: درد نوروپاتیک می‌تواند یکی از دلایل اصلی مؤثر بر کاهش کیفیت خواب باشد و کیفیت خواب پایین و نامطلوب بر عواملی همچون کیفیت زندگی و ادامه درمان تأثیرات نامطلوبی دارد. مطالعه حاضر با هدف بررسی درد نوروپاتیک و تأثیر آن بر کیفیت خواب زنان مبتلا به سرطان پستان پس از رادیوتراپی انجام شد.
روش‌کار: این مطالعه توصیفی- همبستگی از اول فروردین 1396 تا اول اسفند 1397 بر روی زنان مبتلا به سرطان پستان تحت رادیوتراپی در مرکز آموزشی درمانی امام رضا (ع) وابسته به دانشگاه علوم پزشکی تبریز انجام شد. ابزار مورد استفاده شامل مشخصات دموگرافیک، پرسشنامه درد VAS و پرسشنامه اختلال خواب پیترزبورگ بود که درد نوروپاتیک و وضعیت خواب را می سنجیدند. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 20) و آزمون رگرسیون چندمتغیری انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: میانگین شدت درد در بیماران شرکت کننده در مطالعه 03/1±55/6 و میانگین نمره خواب بیماران 20/3±29/12 بود. بر اساس نتایج رگرسیون، متغیرهای سن (012/0=p)، شدت درد (001/0=p)، ماستکتومی (011/0=p)، برداشتن غدد لنفاوی (035/0=p)، تعداد جلسات رادیوتراپی (003/0=p)، سابقه شیمی درمانی (002/0=p) و مرحله بیماری (01/0=p) به‌صورت معناداری اختلال خواب را پیش‌بینی کرد.
نتیجه‌گیری: شیوع درد نوروپاتیک پس از رادیوتراپی در زنان مبتلا به سرطان پستان در مطالعه حاضر بالا بود و این درد به‌عنوان عامل پیش‌بینی‌کننده اختلال خواب در این زنان بود.

کلیدواژه‌ها


عنوان مقاله [English]

Prevalence of neuropathic pain and factors affecting sleep quality in women with breast cancer after radiotherapy

نویسندگان [English]

  • Mehdi Khanbabaei Gol 1
  • Forough Rezvani 2
  • Zahra Ghavami 3
  • Noushin Mobaraki-Asl 4
1 M.Sc. in Nursing, Tuberculosis and Lung Disease Research Center, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
2 BC student in Anesthesia, School of Paramedical, Tabriz University of Medical Sciences, Tabriz, Iran.
3 Gynecologist, Faculty of Medicine and Paramedical, Ardabid University of Medical Sciences, Ardabil, Iran.
4 Fellowship of Gynecology Oncology, Faculty of Medicine and Paramedical, Ardabid University of Medical Sciences, Ardabil, Iran.
چکیده [English]

Introduction: Neuropathic pain can be one of the main causes of decreased sleep quality, and undesirable sleep quality has negative effects on quality of life and treatment continuation. This study was performed with aim to evaluate neuropathic pain and factors affecting sleep quality in women with breast cancer after radiotherapy.
Methods: This descriptive-correlational study was performed from 21March 2017 to 20February 2019 on women with breast cancer undergoing radiotherapy in Imam Reza Educational Center, Tabriz University of Medical Sciences. The tools included demographic characteristics, VAS pain questionnaire, and Pittsburgh Sleep Disorders Questionnaire which measured neuropathic pain and sleep status. Data was analyzed by SPSS software (version 20) and multivariate regression test. P <0.05 was considered statistically significant.
Results: Mean of pain severity in patients participating in the study was 06.55±1.03 and mean score of sleep was 12.29±3.20. According to regression results, the variables of age (P=0.012), pain intensity (P=0.001), mastectomy (P=0.011), lymph nodes removal (P=0.03), number of radiotherapy sessions (P=0.003), history of chemotherapy (P=0.002) and stage of disease (P=0.01) significantly predicted sleep disorder.
Conclusion: Prevalence of neuropathic pain after radiotherapy in women with breast cancer was high in this study, and this pain was the predictor of sleep disorder in these women.

کلیدواژه‌ها [English]

  • Breast Cancer
  • Neuropathic pain
  • Radiotherapy
  • Sleep Quality
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