بررسی ارتباط سطح سرمی ویتامین D با شدت دیسمنوره اولیه و علائم سیستمیک همراه در دانشجویان ساکن خوابگاه‌های دانشگاه علوم پزشکی شهید بهشتی

نوع مقاله: اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، کمیته پژوهشی دانشجویان، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 استاد گروه زنان و مامایی، بیمارستان شهدای تجریش، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

3 استادیار گروه آمار زیستی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

4 دانشیار گروه آمار زیستی، مرکز تحقیقات پرتئومیکس، دانشکده پیراپزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

5 استاد گروه تغذیه، دانشکده بهداشت، دانشگاه علوم پزشکی ایران، تهران، ایران.

6 استادیار گروه مامایی و بهداشت باروری، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

چکیده

مقدمه: برخی مطالعات نشان‌دهنده رابطه بین کمبود ویتامین D3 با بروز دیسمنوره اولیه و علائم سیستمیک همراه آن است، اما رابطه شدت درد با سطح سرمی ویتامین D مشخص نیست، لذا مطالعه حاضر با هدف بررسی رابطه شدت دیسمنوره اولیه و علائم سیستمیک همراه با سطح سرمی ویتامین D انجام شد.
روش‌کار: این مطالعه مقطعی در سال 1397 بر روی 143 نفر از دانشجویان مبتلا به دیسمنوره اولیه ساکن خوابگاه‌های دانشگاه علوم پزشکی شهید بهشتی انجام شد. داده‌های مربوط به سیکل قاعدگی و شدت دیسمنوره اولیه با استفاده از پرسشنامه اطلاعات فردی و وضعیت قاعدگی و خط‌کش درد جمع‌آوری شد. سطح سرمی 25 هیدروکسی ویتامین D3 با دستگاه LIASON به‌روش Chemiluiminescence و در کیت DiaSorin آنالیز شد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 24) و آزمون‌های آماری من‌ویتنی و تی مستقل انجام شد.میزان p‌ کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: بین میانگین درد دیسمنوره اولیه با سطوح سرمی ویتامین D ارتباط معنا‌داری مشاهده نشد (05/0<p). بین شدت سردرد، خستگی، تهوع و استفراغ با سطح سرمی ویتامین D ارتباط معنی‌داری مشاهده شد (001/0p<)، اما این ارتباط با شدت اسهال مشاهده نشد (05/0<p).
نتیجه‌گیری: بین شدت درد دیسمنوره اولیه با سطوح سرمی ویتامین D ارتباط معنی‌داری وجود ندارد؛ اما با شدت سردرد، خستگی، تهوع و استفراغ ارتباط معناداری وجود دارد. انجام مطالعات بزرگ‌تر در جامعه‌ای غیر‌همگون جهت بررسی دقیق‌تر این رابطه پیشنهاد می‌شود.

کلیدواژه‌ها


عنوان مقاله [English]

Relationship between serum vitamin D with severity of primary dysmenorrhea and associated systemic symptoms in dormitories students of Shahid Beheshti University of Medical Sciences

نویسندگان [English]

  • Fatemeh Sadat Rahnemaie 1
  • Maryam Afrakhteh 2
  • Malihe Nasiri 3
  • Farid Zayeri 4
  • Mohammadreza Vafa 5
  • Giti Ozgoli 6
1 M.Sc. Student of Midwifery, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Professor, Department of Obstetrics and Gynecology, Tajrish Shohad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Assistant Professor, Department of Biostatics, , School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Associate professor, Department of Biostatics, Proteomics Research Center, School of Paramedical, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5 Professor, Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
6 Assistant Professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Some studies have shown the relationship between vitamin D3 deficiency, with primary dysmenorrhea and associated systemic symptoms. However, the relationship between pain severity and serum vitamin D level is not known. Therefore, this study was performed with aim to investigate the relationship between the severity of primary dysmenorrhea and associated systemic symptoms with serum levels of vitamin D.
Methods: This cross-sectional study was performed on 143 students with primary dysmenorrhea in dormitories of Shahid Beheshti University of Medical Sciences in 2018. Data related to menstruation cycle and severity of primary dysmenorrhea were collected using demographic questionnaire, menstrual status and pain index. The serum level of 25-hydroxyvitamin D3 was determined by LIASON device, by Chemiluiminescence method and was analyzed in DiaSorin kit. Data were analyzed by SPSS software (version 24) and Mann-Whitney test and independent t-test. PResults: No significant relationship was found between the mean score of primary dysmenorrhea and serum vitamin D levels (P>0.05). There was a significant relationship between severity of headache, fatigue, nausea and vomiting with serum vitamin D levels (P <0.001), but this relationship was not found with severity of diarrhea (P>0.05).
Conclusion: There is no significant relationship between severity of primary dysmenorrhea and serum vitamin D levels, but significant relationship was found with severity of headache, fatigue, nausea and vomiting. Performing larger studies in a non-homogeneous society is suggested for closer evaluation of this relationship.

کلیدواژه‌ها [English]

  • Cholecalciferol
  • Dysmenorrhea
  • Menstrual pain
  • Pain
  • Vitamin D
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